IBRN ETF — Holdings & Analysis
The iShares Neuroscience and Healthcare ETF (IBRN) offers targeted exposure to companies poised to benefit from advancements in neuroscience. With an expense ratio of 0.47%, IBRN provides access to a concentrated portfolio of 57 U.S. and non-U.S. companies. The fund has approximately $0.00B in assets under management and focuses exclusively on the healthcare sector, differentiating it from broader healthcare ETFs. Past performance does not guarantee future results.
iShares Neuroscience and Healthcare ETF (IBRN) ETF — Price, Holdings & Analysis
ETF Overview
Risk Metrics
Expense Ratio
Top Holdings
- Praxis Precision Medicines Inc Ordinary Shares (PRAX): 5.61%
- Axsome Therapeutics Inc (AXSM): 4.53%
- Biogen Inc (BIIB): 4.36%
- Alkermes PLC (ALKS): 4.21%
- Supernus Pharmaceuticals Inc (SUPN): 4.07%
- Scholar Rock Holding Corp (SRRK): 4.06%
- Xenon Pharmaceuticals Inc (XENE): 3.96%
- Denali Therapeutics Inc (DNLI): 3.78%
- ACADIA Pharmaceuticals Inc (ACAD): 3.70%
- PTC Therapeutics Inc (PTCT): 3.64%
Sector Allocation
- Healthcare: 100.0%
- United States: 68.9%
- Canada: 5.7%
- Ireland: 4.5%
- United Kingdom: 3.4%
- Netherlands: 3.4%
- Sweden: 2.9%
- South Korea: 2.5%
- Denmark: 2.1%
- China: 1.8%
- Japan: 1.7%
Dividend Yield
- <a href="/etf/rwde">Direxion MSCI Developed Over Emerging Markets ETF (RWDE)</a> — 0.53% expense ratio
- <a href="/etf/fine">Themes European Luxury ETF (FINE)</a> — 0.35% expense ratio
- <a href="/etf/mj">Amplify Alternative Harvest ETF (MJ)</a> — 0.75% expense ratio
- <a href="/etf/defa">iShares Adaptive Currency Hedged MSCI EAFE ETF (DEFA)</a> — 0.35% expense ratio
- <a href="/etf/psmm">Invesco Moderately Conservative Multi-Asset Allocation ETF (PSMM)</a> — 0.35% expense ratio
- <a href="/etf/gxg">Global X - MSCI Colombia ETF (GXG)</a> — 0.62% expense ratio
- <a href="/etf/omfs">Invesco Russell 2000 Dynamic Multifactor ETF (OMFS)</a> — 0.39% expense ratio
- <a href="/etf/xhb">State Street SPDR S&P Homebuilders ETF (XHB)</a> — 0.35% expense ratio
- <a href="/etf/defa">iShares Adaptive Currency Hedged MSCI EAFE ETF (DEFA)</a> (Equity) — 0.35% ER
- <a href="/etf/uae">iShares MSCI UAE ETF (UAE)</a> (Equity) — 0.59% ER
- <a href="/etf/amca">iShares Russell 1000 Pure U.S. Revenue ETF (AMCA)</a> (Equity) — 0.15% ER
- <a href="/etf/iblc">iShares Blockchain and Tech ETF (IBLC)</a> (Equity) — 0.47% ER
- <a href="/etf/irtr">iShares LifePath Retirement ETF (IRTR)</a> (Multi-Asset) — 0.08% ER
- <a href="/etf/jkk">iShares Morningstar Small-Cap Growth ETF (JKK)</a> (Equity) — 0.06% ER
Risk Metrics
- Beta: 1.20
Questions & Answers
What is IBRN and what does it track?
The iShares Neuroscience and Healthcare ETF (IBRN) seeks to track the investment results of an index composed of U.S. and non-U.S. companies that could benefit from the growth and innovation in neuroscience. This means the fund invests in companies involved in the research, development, and commercialization of treatments and technologies related to neurological disorders and brain health. IBRN provides investors with targeted exposure to this specific area within the broader healthcare sector. The fund's holdings are selected based on their potential to benefit from advancements in neuroscience, offering a focused investment strategy.
What is the expense ratio for IBRN?
The expense ratio for IBRN is 0.47%. This means that for every $10,000 invested in the fund, $47 is used to cover the fund's operating expenses annually. While this is a cost to consider, it's important to weigh it against the potential benefits of the fund's targeted investment strategy. When compared to the average expense ratio for equity ETFs, IBRN's expense ratio is slightly higher.
What are the top holdings in IBRN?
The top holdings in IBRN, as of 2026-03-15, include Praxis Precision Medicines Inc (5.61%), Axsome Therapeutics Inc (4.53%), and Biogen Inc (4.36%). Alkermes PLC (4.21%) and Supernus Pharmaceuticals Inc (4.07%) also rank among the fund's largest allocations. These companies represent a significant portion of IBRN's portfolio and reflect the fund's focus on neuroscience and healthcare innovation. These holdings are primarily in the pharmaceutical and biotechnology industries.
Is IBRN a good long-term investment?
Determining whether IBRN is a suitable long-term investment depends on an individual's investment goals, risk tolerance, and time horizon. IBRN offers targeted exposure to the neuroscience and healthcare sector, which may present growth opportunities but also involves specific risks. The fund's beta of 1.20 suggests higher volatility compared to the broader market. Investors should carefully evaluate the fund's investment strategy, expense ratio, and risk profile before making a decision. Past performance does not guarantee future results.
How does IBRN compare to similar ETFs?
IBRN differentiates itself through its specific focus on neuroscience and healthcare innovation. While other healthcare ETFs may offer broader exposure to the healthcare sector, IBRN targets companies directly involved in neuroscience-related activities. The fund's expense ratio of 0.47% is comparable to other specialized ETFs. With approximately $0.00B in AUM, IBRN is smaller than some of the larger, more established healthcare ETFs, which could impact liquidity and trading volume. Investors should compare IBRN's holdings and investment strategy to those of other healthcare ETFs to determine the best fit for their portfolio.
Does IBRN pay dividends?
As of 2026-03-15, IBRN has a dividend yield of 0.00%. This indicates that the fund does not currently distribute dividends to its shareholders. Investors seeking income-generating investments may want to consider other ETFs with a higher dividend yield. The fund's focus is primarily on capital appreciation through investments in growth-oriented companies within the neuroscience and healthcare sector.