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Otsuka Holdings Co., Ltd. (OTSKY) Stock Analysis

Educational signal · not a buy or sell recommendation · How to read this

$37.08 +$0.29 (+0.79%) |CouncilStrongly Bullish · 78 · A
MCap: $39.0B| P/E Ratio: 14.75| Vol: 13.4K| Target: $40.00 (estimate, not advice)| 52-wk range: $25.30 – $40.92

P/E 14.75 means the share price is 14.75 times one year of earnings per share; the S&P 500 usually sits near 20-25. Market cap $39.0B is the value of all shares combined.

Data from FMP · Methodology

For informational purposes only. Not financial advice. Machine-generated analysis by Stock Expert AI — model gemini-2.0-flash, generated Mar 17, 2026. Editorial oversight is systemic, not page-by-page. Editorially accountable: Sedat ANAK, Founder and Editor-in-Chief. Data sources: Financial Modeling Prep, Yahoo Finance, SEC EDGAR

Quick Answer

Otsuka Holdings Co., Ltd. (OTSKY) trades at $37.08. Otsuka Holdings Co., Ltd. is a global healthcare company based in Japan, with a diversified portfolio spanning pharmaceuticals, nutraceuticals, consumer products, and other businesses. Market cap: $39.0B, Sector: Healthcare.

Price as of Sep 11, 2026 · Last analyzed: Mar 17, 2026
Otsuka Holdings Co., Ltd. is a global healthcare company based in Japan, with a diversified portfolio spanning pharmaceuticals, nutraceuticals, consumer products, and other businesses. The company's pharmaceutical segment focuses on therapeutic areas such as oncology, cardiovascular, and renal diseases, while its consumer product offerings include well-known brands like Pocari Sweat and Calorie Mate.

OTSKY stock analysis for 2026: The stored analyst price target for Otsuka Holdings Co., Ltd. is $40.00; its date is unknown, so no upside or downside is derived from it against the current price of $37.08. Key factors: analyst coverage, company fundamentals.

Watch the OTSKY film Every key number, told as a short cinematic story — just press play. ~2 min

These figures come from statements filed 12 months ago — the most recent this company has published.

Council Score · Weighted Average of 3 Disciplines
Strongly Bullish 78/100 · A

OTSKY: 2/2 scored disciplines lean bullish. Dominant signal: Izzy Englander bullish.

How is this calculated? →
Legends Council · 5 Legends + Moon AI

AI simulations built from the named investors' published principles. Not affiliated with, endorsed by, or the opinion of these individuals. How these lenses are built

Englander-style lens (simulated)Izzy Englander
Favorable read
Klarman-style lens (simulated)Seth Klarman
Favorable read
Moon AI lens (model)
Favorable read
Munger's Mindset · Balance Sheet & Valuation
Financial Health
Moderate
Margin of Safety
Undervalued
Council Score · Weighted Average of 3 Disciplines · See tabs for details →
The lenses are modelled on the published principles of the investors named. We are not affiliated with them, they have not endorsed this, and it is not their opinion of this stock.

Otsuka Holdings Co., Ltd. (OTSKY) Healthcare & Pipeline Overview

CEOMakoto Inoue
Employees37,758
HeadquartersTokyo, JP
IPO Year2012

Otsuka Holdings Co., Ltd. is a diversified healthcare company with a strong presence in pharmaceuticals, nutraceuticals, and consumer products. Headquartered in Japan, the company leverages its research and development capabilities to address unmet medical needs and expand its portfolio of well-established consumer brands, operating in a global market with a focus on innovation.

Data Provenance | Financial Data Quantitative Analysis Analysis: Mar 17, 2026

What Is the Investment Thesis for OTSKY?

AI-written as of Mar 17, 2026 — figures and tone reflect the data available then, not today's score.

Otsuka Holdings presents a stable investment profile, supported by its diversified revenue streams and established presence in both pharmaceutical and consumer product markets. With a P/E ratio of 14.75 and a profit margin of 14.7%, the company demonstrates consistent profitability. A dividend yield of 1.27% offers a modest income stream for investors. Growth catalysts include the expansion of its pharmaceutical pipeline and the continued success of its consumer brands in emerging markets. However, potential risks include regulatory challenges in the pharmaceutical industry and currency fluctuations impacting its international operations. The company's low beta of -0.08 suggests a relatively low correlation with overall market movements, potentially offering downside protection during market volatility.

Based on FMP financials and quantitative analysis

OTSKY Key Highlights

AI-written as of Mar 17, 2026 — figures and tone reflect the data available then, not today's score.

Market capitalization of $39.0B, reflecting its significant size and established position in the healthcare industry.

  • P/E ratio of 14.75, indicating a reasonable valuation compared to its earnings.
  • Profit margin of 14.7%, demonstrating efficient operations and profitability.
  • Gross margin of 71.7%, highlighting the company's ability to maintain strong pricing power and manage costs effectively.
  • Dividend yield of 1.27%, providing a steady income stream for investors.

Who Are OTSKY's Competitors?

OTSKY is benchmarked below against 8 industry peers on price, market cap, and our AI MoonshotScore.

Company Price Change Market Cap MoonshotScore
ALPMF Astellas Pharma Inc. $15.45 -1.28% $27.7B
BAYRY Bayer AG $14.07 -1.54% $55.3B
FSNUF Fresenius SE & Co. KGaA $54.35 0.00% $30.6B
GIKLY Grifols, S.A. $5.75 0.00% $15.1B
BIIB Biogen Inc. $215.43 +2.23% $31.8B 645-pillar
GSK GSK plc $48.02 -0.21% $96.2B 875-pillar
SNY Sanofi $42.69 -0.08% $103B 835-pillar
BMY Bristol-Myers Squibb Company $63.34 -0.64% $129B 905-pillar

AI Score by Stock Expert AI · Price data: FMP / Yahoo Finance

What Are OTSKY's Key Strengths?

Diversified revenue streams across pharmaceuticals, nutraceuticals, and consumer products.

  • Strong brand recognition for key consumer products.
  • Established distribution network in Japan and other key markets.
  • Solid financial performance with consistent profitability.

What Are OTSKY's Weaknesses?

Reliance on key products for a significant portion of revenue.

  • Exposure to regulatory risks in the pharmaceutical industry.
  • Limited presence in some emerging markets compared to competitors.
  • Dependence on third-party manufacturers for some products.

What Could Drive OTSKY Stock Higher?

Potential regulatory approvals for new pharmaceutical products in key markets.

  • Expansion of consumer product lines into new geographic regions.
  • Strategic partnerships and acquisitions to enhance product portfolio and market reach.
  • Continued investment in research and development to drive innovation and pipeline growth.

What Are the Key Risks for OTSKY?

Regulatory setbacks or delays in the approval of new pharmaceutical products.

  • Increasing competition from generic drug manufacturers and biosimilars.
  • Currency fluctuations impacting revenue and profitability from international operations.
  • Product liability claims and recalls affecting brand reputation and financial performance.
  • Economic downturns reducing consumer spending on nutraceutical and consumer products.

What Are the Growth Opportunities for OTSKY?

  • Expansion of Pharmaceutical Pipeline: Otsuka can drive growth by investing in research and development to expand its pipeline of pharmaceutical products, particularly in areas such as oncology and central nervous system disorders. The global oncology market is projected to reach $286.6 billion by 2031, offering significant revenue potential. Successful clinical trials and regulatory approvals can lead to substantial revenue growth over the next 3-5 years.
  • Emerging Markets Penetration: Otsuka can capitalize on the growing demand for healthcare products in emerging markets, such as Asia and Latin America. These regions offer significant growth opportunities due to increasing disposable incomes and expanding healthcare infrastructure. By tailoring its product offerings and distribution strategies to local market needs, Otsuka can achieve double-digit revenue growth in these regions over the next 5-10 years.
  • Strategic Acquisitions and Partnerships: Otsuka can pursue strategic acquisitions and partnerships to expand its product portfolio and geographic reach. Acquiring companies with complementary technologies or market access can accelerate growth and enhance its competitive position. The company can target acquisitions in the nutraceutical and consumer health sectors to diversify its revenue streams and capitalize on synergies. These strategic moves can be executed within the next 2-3 years.
  • Digital Health Initiatives: Otsuka can leverage digital health technologies to improve patient outcomes and enhance its product offerings. This includes developing mobile apps, wearable devices, and telehealth platforms that integrate with its pharmaceutical and consumer health products. The global digital health market is expected to reach $660 billion by 2027, presenting a significant opportunity for Otsuka to innovate and differentiate itself from competitors. These initiatives can be launched and scaled over the next 3-5 years.
  • Focus on Women's Health: Otsuka can further develop and market products specifically targeted at women's health, such as its EQUELLE product. The global women's health market is growing rapidly, driven by increasing awareness of women's health issues and demand for innovative solutions. By expanding its product portfolio and marketing efforts in this area, Otsuka can capture a larger share of this growing market over the next 2-3 years.

What Are OTSKY's Competitive Advantages?

  • Strong brand recognition for consumer products like Pocari Sweat and Calorie Mate, creating customer loyalty and repeat purchases.
  • Diversified product portfolio across pharmaceuticals, nutraceuticals, and consumer products, reducing reliance on any single product or market.
  • Established distribution network in Japan and other key markets, providing a competitive advantage in reaching customers.
  • Research and development capabilities in pharmaceuticals, enabling the company to develop innovative products and maintain a competitive edge.

What Does OTSKY Do?

Otsuka Holdings Co., Ltd., founded in 1921 and headquartered in Tokyo, Japan, has evolved from a small chemical company into a global healthcare conglomerate. The company operates across pharmaceuticals, nutraceuticals, consumer products, and other diverse segments. Its pharmaceutical division develops and markets products in key therapeutic areas, including oncology, cardiovascular, renal, digestive, and ophthalmology. Notable pharmaceutical products include treatments for schizophrenia and other central nervous system disorders. Otsuka's nutraceutical and consumer product lines feature popular brands such as Pocari Sweat, a rehydration drink; Calorie Mate, a balanced nutritional food; and Oronine H Ointment, a widely used antiseptic. These products have established strong market positions, particularly in Asia. The company also has a presence in medical devices, diagnostics, and intravenous solutions. Otsuka's global reach extends through subsidiaries and partnerships, allowing it to distribute its products and conduct research and development activities worldwide. The company's diversified business model provides resilience and opportunities for synergistic growth across its various segments.

What Products and Services Does OTSKY Offer?

  • Develops and markets pharmaceutical products for various therapeutic areas, including oncology, cardiovascular, and central nervous system disorders.
  • Manufactures and distributes nutraceutical products, such as vitamin and mineral supplements.
  • Produces and sells consumer products, including beverages like Pocari Sweat and nutritional foods like Calorie Mate.
  • Offers medical devices and diagnostics solutions.
  • Provides intravenous solutions and other hospital products.
  • Operates a hotel business.

How Does OTSKY Make Money?

  • Develops and commercializes pharmaceutical products, generating revenue through sales to healthcare providers and patients.
  • Manufactures and distributes nutraceutical and consumer products through retail channels, including supermarkets, pharmacies, and convenience stores.
  • Generates revenue from medical devices and diagnostics through sales to hospitals and clinics.
  • Operates a hotel, generating revenue from room rentals, food and beverage sales, and other hospitality services.

What Industry Does OTSKY Operate In?

Otsuka Holdings operates within the global healthcare industry, which is characterized by increasing demand for innovative pharmaceuticals, nutraceuticals, and consumer health products. The industry is driven by factors such as an aging population, rising healthcare expenditures, and advancements in medical technology. Otsuka competes with major pharmaceutical companies like Bayer (BAYRY) and consumer health giants. The competitive landscape is intense, with companies vying for market share through research and development, strategic partnerships, and marketing efforts. Otsuka's diversified portfolio and strong presence in both developed and emerging markets position it favorably within this dynamic industry.

Who Are OTSKY's Key Customers?

  • Healthcare providers, including physicians, hospitals, and clinics.
  • Patients who use Otsuka's pharmaceutical products to treat various medical conditions.
  • Consumers who purchase Otsuka's nutraceutical and consumer products for health and wellness purposes.
  • Hotels guests.
Model self-rating on this text: 71% (not a measure of the evidence) Updated: Mar 17, 2026

Research confidence

Medium 60/100

Enough evidence to be useful, with gaps worth knowing about.

  • Scoring coverage unknown
  • Price is current
  • Latest filing 73 days ago
  • Covered by analysts
  • Reported in JPY, converted to USD

MoonshotScore History

Recorded daily since 2026-08-23 · 20 snapshots

2026-08-23 58
2026-08-27 58
2026-08-31 58
2026-09-04 58
2026-09-08 58
2026-09-11 58

What changed?

The score has stayed at 58.

Over the same 19 days the stock moved -3.8%.

Company Profile

Otsuka Holdings Co., Ltd. operates in the Drug Manufacturers - General industry within the Healthcare sector. It is headquartered in Tokyo, JP. The company is led by CEO Makoto Inoue. OTSKY has traded publicly since 2012.

ROE 13%

Key Financial Metrics

Return on equity for Otsuka Holdings Co., Ltd. stands at 12.8%, a gauge of how efficiently it converts shareholder capital into profit. Return on assets is 8.9%, showing how much profit it generates from its asset base. OTSKY trades at a trailing price-to-earnings ratio of 14.75, below the Healthcare sector average of ~21.50x. Its free cash flow yield is 5.6%, a gauge of the cash the business throws off relative to its market value. A current ratio of 2.33 indicates the company holds enough short-term assets to cover its near-term obligations. Its earnings yield is 6.7%, the inverse of the P/E and a quick read on earnings relative to price.

OTSKY Valuation & Market Position

With a $39.0B market cap, Otsuka Holdings Co., Ltd. sits in the large-cap segment of the market.

Quarterly Financial Performance: Otsuka Holdings Co., Ltd.

Revenue for Otsuka Holdings Co., Ltd. came in at $4.63B during Q2 FY2026, a 10.8% improvement versus the preceding quarter. The company recorded net income of $773.1M, with diluted EPS of $0.73. Quarter-over-quarter revenue has been mixed, typical for a large-cap company operating in Healthcare. Across the four most recent quarters, OTSKY averaged $0.64 in diluted EPS.

F-Score 7/9

Financial Health

Otsuka Holdings Co., Ltd.'s Piotroski F-Score is 7/9, a 9-point checklist of profitability, leverage and efficiency — signaling solid underlying fundamentals. Its Altman Z-Score of 5.34 places it in the safe zone, indicating low near-term bankruptcy risk.

7/8 beats

Earnings Track Record

Otsuka Holdings Co., Ltd. has beaten Wall Street's EPS estimate in 7 of its last 8 reported quarters — a consistent record of delivering on expectations. Reported results have landed about 43.1% above estimates on average.

OTSKY Financials

Fundamental Snapshot

Revenue Growth (FY)
+11.1%
Net Income Growth (FY)
+11.0%
EPS Growth (FY)
+13.4%
Free Cash Flow Growth (FY)
+47.0%
P/E (TTM)
14.75
Return on Equity (TTM)
+12.8%
Current Ratio
2.3
EV/EBITDA (TTM)
8.9

Based on FMP financials and quantitative analysis · FY 2025

Bull Case vs Bear Case

Bull Case

  • Diversified revenue streams across pharmaceuticals, nutraceuticals, and consumer products.
  • Strong brand recognition for key consumer products.
  • Established distribution network in Japan and other key markets.
  • Solid financial performance with consistent profitability.

Bear Case

  • Reliance on key products for a significant portion of revenue.
  • Exposure to regulatory risks in the pharmaceutical industry.
  • Limited presence in some emerging markets compared to competitors.
  • Dependence on third-party manufacturers for some products.

AI-generated arguments based on insider flow, news sentiment and technicals — not financial advice · March 2026

Recent Quarterly Results

Quarter Revenue Net Income EPS
Q2 FY2026 $4.63B $773M $0.73
Q1 FY2026 $4.18B $652M $0.62
Q4 FY2025 $4.31B $434M $0.41
Q3 FY2025 $4.22B $822M $0.78

Q2 FY2026 · filed 30 Jun 2026 · Financial Modeling Prep

Based on FMP financials and quantitative analysis · Converted to USD from JPY at today's rate

OTSKY Latest News

OTSKY Analyst Consensus

Consensus Rating

Aggregated Buy/Hold/Sell recommendations collected by Financial Modeling Prep for OTSKY.

Price Targets

Consensus target: $40.00

OTSKY MoonshotScore

MoonshotScore is Stock Expert AI's proprietary 0-100 research rating, not a buy or sell recommendation. No MoonshotScore is published for OTSKY; grades run from A+ (80-100) to F (below 30).

Leadership: Makoto Inoue

Managing Director

Makoto Inoue serves as a Managing Director at Otsuka Holdings Co., Ltd. His career within Otsuka spans several decades, during which he has held various leadership positions across different divisions. He has been instrumental in driving the company's global expansion and diversification strategies. Inoue's expertise lies in strategic planning, business development, and operational management. He is known for his focus on innovation and commitment to improving patient outcomes.

Track Record: Under Makoto Inoue's leadership, Otsuka Holdings has achieved significant milestones, including the successful launch of several key pharmaceutical products and the expansion of its consumer product portfolio. He has also overseen strategic acquisitions and partnerships that have strengthened the company's competitive position in the global healthcare market. His tenure has been marked by a focus on sustainable growth and creating long-term value for shareholders.

Otsuka Holdings Co., Ltd. ADR Information Unsponsored

An American Depositary Receipt (ADR) is a certificate representing shares of a foreign company trading on U.S. stock exchanges. OTSKY is an unsponsored Level 1 ADR, meaning it trades over-the-counter (OTC) without direct involvement from Otsuka Holdings. This allows U.S. investors to easily invest in Otsuka Holdings without dealing with foreign exchanges.

  • Home Market Ticker: Tokyo Stock Exchange, Japan
  • ADR Level: 1
  • ADR Ratio: 1:1
  • Home Market Ticker: OTSK
Currency Risk: As an ADR, OTSKY is subject to currency risk. The value of the ADR is affected by fluctuations in the exchange rate between the Japanese Yen (JPY) and the U.S. Dollar (USD). If the Yen depreciates against the Dollar, the value of OTSKY may decrease for U.S. investors, and vice versa.
Tax Implications: Dividends paid on OTSKY shares are subject to Japanese withholding tax. The standard withholding tax rate is typically around 15%, but this may vary depending on tax treaties between Japan and the investor's country of residence. U.S. investors may be able to claim a foreign tax credit on their U.S. tax return for the amount of Japanese withholding tax paid.
Trading Hours: The Tokyo Stock Exchange (TSE) operates on Japan Standard Time (JST), which is 13 hours ahead of Eastern Standard Time (EST). This means that when the TSE opens at 9:00 AM JST, it is 8:00 PM EST the previous day. As OTSKY trades OTC in the U.S., its trading hours are generally aligned with the U.S. market hours, but liquidity may be affected when the TSE is closed.

OTSKY OTC Market Information

The OTC Other tier represents the lowest tier of the OTC market, indicating that OTSKY may not meet the minimum financial and disclosure requirements of higher tiers like OTCQX or OTCQB. Companies in this tier often have limited information available to investors and may be subject to less regulatory oversight compared to companies listed on major exchanges like the NYSE or NASDAQ. Investing in OTC Other stocks carries higher risks due to the potential for fraud, lack of transparency, and limited liquidity.

  • OTC Tier: OTC Other
Liquidity: Liquidity for OTSKY on the OTC market is likely to be limited, given its OTC Other tier status. This can result in wider bid-ask spreads and difficulty in buying or selling large quantities of shares without significantly impacting the price. Investors should be prepared for potential price volatility and execution challenges when trading OTSKY.
OTC Risk Factors:
  • Limited liquidity due to low trading volume on the OTC market.
  • Lack of transparency and potential for incomplete or unreliable financial information.
  • Higher risk of fraud or manipulation compared to stocks listed on major exchanges.
  • Limited regulatory oversight and investor protection.
  • Potential for delisting or suspension of trading due to non-compliance with OTC market requirements.
Due Diligence Checklist:
  • Verify the availability and quality of financial reports from Otsuka Holdings.
  • Research the company's management team and their track record.
  • Assess the company's business model and competitive position in the healthcare industry.
  • Evaluate the risks associated with investing in an OTC stock, including limited liquidity and regulatory oversight.
  • Consult with a financial advisor to determine if OTSKY is a suitable investment for your portfolio.
  • Check for any news or regulatory filings that may impact the company's stock price.
  • Understand the currency risk associated with investing in a Japanese company.
Legitimacy Signals:
  • Otsuka Holdings is a well-established company with a long operating history.
  • The company has a diversified product portfolio across pharmaceuticals, nutraceuticals, and consumer products.
  • Otsuka Holdings has a global presence and established distribution network.
  • The company has a history of innovation and research and development in the healthcare industry.
  • Otsuka Holdings has a market capitalization of $39.0B, indicating a substantial company.

OTSKY Healthcare Stock FAQ

Is OTSKY a good stock?

Stock Expert AI does not rate OTSKY buy, sell or hold. Otsuka Holdings Co., Ltd. has no MoonshotScore yet; read the financial checkup, analyst consensus and risks directly. Whether it fits is your call: check what it sells, whether it earns, what the price assumes, and what would prove you wrong.

What does Otsuka Holdings Co., Ltd. do?

Otsuka Holdings Co., Ltd. is a global healthcare company with a diversified business portfolio encompassing pharmaceuticals, nutraceuticals, consumer products, and other segments.

What are the key factors to evaluate for OTSKY?

Evaluate OTSKY on fundamentals, analyst consensus, and risk factors. P/E: 14.75x vs the S&P 500's ~20-25x. With a P/E ratio of 14.75 and a profit margin of 14.7%, the company demonstrates consistent profitability. Not financial advice.

How frequently does OTSKY data refresh on this page?

OTSKY's price was last updated on Sep 11, 2026 and refreshes on page view during U.S. market hours; the quote is a provider snapshot, not an exchange feed. Fundamentals follow quarterly filings. V2 calculations are scheduled daily at 10:15 UTC; the score's own date shows its last successful run.

What has driven OTSKY's recent stock price performance?

Otsuka Holdings Co., Ltd. (OTSKY) moves on earnings results, analyst revisions, sector rotation, and market sentiment. Notable catalyst: Diversified revenue streams across pharmaceuticals, nutraceuticals, and consumer products. See the News tab for the latest drivers. Past performance does not predict future results.

Should investors consider OTSKY overvalued or undervalued right now?

Otsuka Holdings Co., Ltd. (OTSKY) trades at 14.75x earnings. Compare P/E, P/S, and EV/EBITDA against sector peers for a full view.

Can I buy fractional shares of OTSKY?

Yes, most major brokerages offer fractional shares of Otsuka Holdings Co., Ltd. (OTSKY) with no minimum purchase requirement. This means you can invest any dollar amount regardless of the share price. Check your brokerage platform for specific terms, fees, and fractional share availability.

How can I track OTSKY's earnings and financial reports?

Otsuka Holdings Co., Ltd. (OTSKY) reports quarterly earnings approximately 4-6 weeks after each fiscal quarter ends. You can track earnings dates, revenue and EPS estimates, and actual results on this page's Financials tab. Earnings surprises (beats or misses) often cause significant short-term price moves. Your brokerage can send alerts for OTSKY earnings announcements.

Disclaimer: This content is for informational purposes only and does not constitute investment advice. Always do your own research and consult a financial advisor.

Official Resources

Price as of Analysis updated

No publishable V2 score is available for this stock yet.

Data Sources & Methodology
Market data powered by Financial Modeling Prep & Yahoo Finance. AI analysis by Stock Expert AI proprietary algorithms. Technical indicators via industry-standard calculations. Last updated: .
Data Provenance
Sources: Financial Modeling Prep (FMP) — Primary · Yahoo Finance — Fallback · Alpaca — Tertiary
Last fetched:
Cache TTL: Quote 5min · Profile 7d · Financials 7d · Insider 48h
How we use AI: Numbers are pulled directly from FMP & Yahoo Finance — our AI writes the analysis, it never edits the figures.
Data provided as-is for educational purposes. Not financial advice. Methodology

Data provided for informational purposes only.

Analysis Notes
  • Information is based on available data and may be subject to change.
Data Sources
Financial Modeling Prep (FMP)Stock Expert AI proprietary analysis

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