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Krystal Biotech, Inc. (KRYS) Stock: Price, Forecast & Analyst Target

Krystal Biotech, Inc. (KRYS) — MoonshotScore 97/100 (Exceptional band), calculated Oct 4, 2026. Price $322.28 (-0.93%), as of the Oct 2, 2026 trading session; market cap $9.54B. Expected results Nov 2, 2026.

Educational signal · not a buy or sell recommendation · How to read this

$322.28 −$3.03 (-0.93%) Market Cap $9.54B

Krystal Biotech, Inc. · KRYS · NASDAQ · Healthcare · Biotechnology

Research dated 2026-09-13: Krystal Biotech develops redosable gene therapies for severe orphan diseases, with B-VEC at the front of a broader dermatology and rare-disease pipeline. Reported economics no longer resemble a pre-revenue biotechnology developer: sales, profit, and operating cash flow are established, while liquidity continues to build. The case now rests on whether that revenue base can keep expanding without the expense base outrunning demand.

Price as of Oct 2, 2026

Key Statistics

97 of 100

MoonshotScore v2 · Krystal Biotech (KRYS)

Exceptional
Business Quality Elite (96)
Financial Safety Fortress (97)
Valuation Rich (39)
Growth Durability Compounding (98)
Momentum Surging (80)
Why this rating? Method, drivers & history

Bands for the MoonshotScore: Exceptional 80-100 · Strong 65-79 · Fair 45-64 · Weak below 45.

  • Business Quality — Is this a genuinely good business?
  • Financial Safety — Could this blow up on me?
  • Valuation — Am I paying a fair price?
  • Growth Durability — Is the growth real and likely to last?
  • Momentum — Is the market already moving on this?
The ten-second read ·

Elite quality, a fortress balance sheet and elite growth, with no real weak spot — fairly priced, so not a bargain entry; the market is already moving on it. Business Quality: Elite; Financial Safety: Fortress; Valuation: Rich; Growth Durability: Compounding; Momentum: Surging.

  • quarterly revenue $119M (Q2 FY2026, quarter ended Jun 2026)
  • EPS beat 7 of 8
  • Altman Z 42.52 · Piotroski F 5

Helping: business quality, balance-sheet strength, durable growth, positive momentum

What has the MoonshotScore done over time?

MoonshotScore snapshots recorded for KRYS (29 recorded, newest six shown)
RecordedScoreBand
98Exceptional
98Exceptional
98Exceptional
98Exceptional
98Exceptional
98Exceptional

The score moved from 98 in the stored Oct 3, 2026 snapshot to 97 in the current publication computed Oct 4, 2026 (-1); the largest pillar moves were Momentum +1. This current publication is not yet represented in the immutable snapshot archive.

Calculation uses the most recent completed US trading session. Live price changes do not update the score immediately.

Computed · Educational signal · not a buy or sell recommendation · How the MoonshotScore is computed →

Price & valuation

Dates shown where recorded
MeasureValueAs of
Latest provided price$322.28
Change on the day-0.93%
52-week range$179.19–$382.54
Market capitalisation$9.54B
Price / earnings (trailing)38.97
Shares traded on the day426.1K
Beta (volatility vs the S&P 500)0.54

Price & events

Weekly closing price with reported quarters marked Weekly closing price from Sep 5, 2025 to Oct 2, 2026: low $144, high $375, latest $322. 4 reported quarters marked, 4 above and 0 below the recorded estimate. $375 $144 high $375 Nov 3, 2025 · Earnings results · reported above the recorded estimate · close $1981Feb 17, 2026 · Earnings results · reported above the recorded estimate · close $2622May 4, 2026 · Earnings results · reported above the recorded estimate · close $2663Aug 3, 2026 · Earnings results · reported above the recorded estimate · close $3414 Sep 5, 2025 Oct 2, 2026 · $322 $150Sep 5, 2025$164Sep 19, 2025$183Oct 3, 2025$190Oct 17, 2025$198Oct 31, 2025$206Nov 14, 2025$218Nov 28, 2025$245Dec 12, 2025$252Dec 26, 2025$261Jan 9, 2026$282Jan 23, 2026$273Feb 6, 2026$262Feb 20, 2026$254Mar 6, 2026$252Mar 20, 2026$261Apr 2, 2026$274Apr 17, 2026$266May 1, 2026$306May 15, 2026$309May 29, 2026$318Jun 12, 2026$372Jun 26, 2026$366Jul 10, 2026$335Jul 24, 2026$326Aug 7, 2026$347Aug 21, 2026$358Sep 4, 2026$337Sep 18, 2026$322Oct 2, 2026

Triangles mark reported quarters on the line: pointing up is above the recorded estimate, down is below, a diamond means no estimate on file. Numbers key to the dated list. Point at or tab to any week for its close.

Events behind the price

  • · Earnings results · above the recorded estimate
  • · Earnings results · above the recorded estimate
  • · Earnings results · above the recorded estimate
  • · Earnings results · above the recorded estimate

Results dates follow the earnings feed; call dates follow the transcript provider. Nearby dates do not establish that an event caused a price move.

Upcoming events

As of

  1. Next results dueProvider estimate

The provider's estimated date can change.

What to watch next

Council Score · weighted blend of 2 available disciplines

Council score for Krystal Biotech (KRYS): Strongly Bullish

82/100 · A+

Council is a separate blend of available disciplines; MoonshotScore above remains the five-pillar research rating.

5-Factor Breakdown

Growth Durability Strong
Momentum Moderate
Business Quality Strong
Financial Safety Strong
Valuation Weak

Legends Council

5 lenses, 5 current

AI simulations built from the named investors' published principles. Not affiliated with, endorsed by, or the opinion of these individuals. How these lenses are built

Dalio-style lens (simulated) Ray Dalio Favorable read
Griffin-style lens (simulated) Ken Griffin Favorable read
Englander-style lens (simulated) Izzy Englander Neutral read
Klarman-style lens (simulated) Seth Klarman Neutral read
Moon AI lens (model) Favorable read

Read on: Oct 4, 2026

Munger's Mindset

Balance Sheet & Valuation · historical

Financial Health Strong
Margin of Safety Fairly Valued
Profit Margin Strong
Revenue Growth Strong
Debt/Equity Strong
ROE Strong
Gross Margin Strong

Read on: Sep 9, 2026 · older than the 27 hours refresh window; not a current reading

How to read these bars and different assessments

Council is a separate blend of available disciplines; MoonshotScore above remains the five-pillar research rating.

Bars show each model's ordered assessment on its own scale, not a probability or a comparable investment return. The adjacent words give the assessment; more filled segments indicate a stronger model reading.

On Sep 9, 2026, the Munger lens read the price at that time as fairly valued against its own estimate of value.

Readings on this page are from Oct 4, 2026, except a card that shows its own read date.

Watch the KRYS film — every key number, told as a short cinematic story

~2 min · open the film

1 · What is it?

What is Krystal Biotech (KRYS), and what does it report?

Short answer · as of

Krystal is a gene-therapy developer built around treatments that can be administered repeatedly rather than a diversified drug manufacturer.

Research dated 2026-09-13.

Krystal is a gene-therapy developer built around treatments that can be administered repeatedly rather than a diversified drug manufacturer. Its programs span severe inherited skin disorders, cystic fibrosis, and aesthetic dermatology, with B-VEC identified as the most advanced candidate. The economic task is to translate those programs into patient treatment; clinical progress by itself is not revenue.

Sources (as of 2026-09-13): Business description; Sector / industry (provider taxonomy)

2 · Latest results

What do the latest results show for Krystal Biotech (KRYS)?

Short answer · as of

The most recent reported quarter, Q2 FY2026, carried revenue of $119M.

Research dated 2026-09-13.

Revenue advanced again in the latest reported period, while gross profit kept pace. Research spending and selling, general, and administrative expense each eased from the preceding period, allowing operating profit to rise even as net profit declined modestly. The immediate mechanism was operating leverage within the reported cost base, not a reduction in gross profitability.

Sources (as of 2026-09-13): Quarterly income statement (USD thousands)

Where is operating spending going?

Revenue alongside research and development, selling, general and administrative expenses, and the FMP standardized operating result.

Where is operating spending going? — FMP standardized evidence
Period endRevenueR&DSG&AFMP standardized operating result
Jun 30, 2026Not availableNot availableNot availableNot available
Mar 31, 2026Not availableNot availableNot availableNot available
Dec 31, 2025Not availableNot availableNot availableNot available
Sep 30, 2025Not availableNot availableNot availableNot available

USD. The operating result is the FMP-standardized value supplied by FMP; it may differ from a filing’s GAAP loss from operations when the provider classifies separately presented items differently. It is not net income or cash flow.

Did results meet expectations?

Reported earnings and revenue alongside the estimates recorded by the provider.

Latest report · revenue
$119.22M Aug 3, 2026
Latest report · revenue estimate
$120.93M Aug 3, 2026
Latest report · revenue vs estimate
Below estimate Aug 3, 2026
Latest report · EPS vs estimate
Above estimate Aug 3, 2026
Did results meet expectations? — reported evidence
Report dateRevenue · reportedRevenue · estimateEPS · reportedEPS · estimate
Aug 3, 2026$119.22M$120.93M$1.7900$1.7000
May 4, 2026$116.36M$112.11M$1.8300$1.4500
Feb 17, 2026$107.11M$105.35M$1.7000$1.6200
Nov 3, 2025$97.80M$105.30M$2.6600$1.1200

Dates are report dates, not fiscal period ends. Revenue is in USD; EPS is USD per share, rounded to four decimals. The earnings feed does not establish a basic, diluted or adjusted basis. Earnings-feed EPS may differ from statement EPS; the two series are not combined.

Quarterly income statement — 4 quarters
Revenue, net income and earnings per share by quarter
PeriodRevenueNet incomeEPS
Q2 FY2026$119M$55M$1.79 (diluted)
Q1 FY2026$116M$56M$1.83 (diluted)
Q4 FY2025$107M$51M$1.72 (diluted)
Q3 FY2025$98M$79M$2.66 (diluted)
3 · Financial strengths and risks

What are the financial strengths and risks for Krystal Biotech (KRYS)?

Short answer

Cash and short-term investments were $0.00 at the Jun 30, 2026 balance-sheet date. This figure does not establish a cash runway.

Research dated 2026-09-13.

Krystal carries substantial cash and short-term investments, an additional pool of long-term investments, and little debt. Positive operating cash flow throughout the displayed run, paired with comparatively modest capital spending, has allowed liquid resources to rise while the company continues funding research and commercial overhead.

Sources (as of 2026-09-13): Cash, investments and debt; Cash and investment components; Cash and short-term investments over time (USD millions); Operating cash flow by quarter (USD millions)

4 · What to check next?

What should you watch next at Krystal Biotech (KRYS)?

Short answer · as of

The next earnings report is expected on Nov 2, 2026.

Research dated 2026-09-13.

Krystal’s scheduled earnings release puts revenue continuity, operating leverage, and cash conversion in focus. Useful confirmation would be another advance in revenue accompanied by resilient gross profit, controlled operating expenses, positive operating cash flow, and further preservation of liquidity.

Sources (as of 2026-09-13): Next earnings report; Quarterly income statement (USD thousands); Operating cash flow by quarter (USD millions); Cash and short-term investments over time (USD millions)

What the records here don't tell us

  • No forward revenue or earnings estimate is on file.

Checked against the records this page reads, on the dates shown above.

5 · Peer comparison

How does Krystal Biotech compare with its peers?

Short answer

Krystal Biotech's score ranks 2nd of 13 in the bounded comparison shown, against 12 same-model peers. These are company scores, not expected investment returns. The set lists named competitors first, then companies in the same data-provider industry classification closest in market value; that classification is the provider's, not our judgment of business similarity.

Research dated 2026-09-13.

Development-stage rare-disease companies commonly depend on external capital while awaiting commercial validation; Krystal already reports recurring revenue, operating profit, net income, and positive operating cash flow. Yet its strategic identity remains that of a focused redosable gene-therapy platform rather than a diversified commercial biopharma business. That combination makes present earnings quality and candidate progression equally relevant comparisons.

Sources (as of 2026-09-13): Business description; Annual revenue and net result (USD millions); Quarterly income statement (USD thousands); Operating cash flow by quarter (USD millions)

Peer set — price, market value and MoonshotScore
CompanyPriceMarket valueScore
Exelixis, Inc. (EXEL) Same industry, near in market value$58.39 Oct 2, 2026$14.7B98 5-pillar Oct 4, 2026
Krystal Biotech (KRYS) — this page$322.28$9.54B97
Ligand Pharmaceuticals Incorporated (LGND) Same industry, near in market value$302.96 Oct 2, 2026$6.07B96 5-pillar Oct 4, 2026
Bio-Techne Corporation (TECH) Same industry, near in market value$72.40 Oct 2, 2026$11.3B93 5-pillar Oct 4, 2026
Corcept Therapeutics Incorporated (CORT) Same industry, near in market value$116.23 Oct 2, 2026$12.6B91 5-pillar Oct 4, 2026
Neurocrine Biosciences, Inc. (NBIX) Same industry, near in market value$143.18 Oct 2, 2026$14.4B90 5-pillar Oct 4, 2026
Caris Life Sciences, Inc. (CAI) Same industry, near in market value$28.30 Oct 2, 2026$8.00B89 5-pillar Oct 4, 2026
Halozyme Therapeutics, Inc. (HALO) Same industry, near in market value$109.86 Oct 2, 2026$13.0B88 5-pillar Oct 4, 2026
Ascendis Pharma A/S (ASND) Same industry, near in market value$227.87 Oct 2, 2026$14.2B88 5-pillar Oct 4, 2026
Protagonist Therapeutics, Inc. (PTGX) Named competitor$140.06 Oct 2, 2026$9.01B76 5-pillar Oct 4, 2026
Belite Bio, Inc. (BLTE) Same industry, near in market value$159.56 Oct 2, 2026$6.40B69 5-pillar Oct 4, 2026
TG Therapeutics, Inc. (TGTX) Named competitor$54.29 Oct 2, 2026$8.31B65 5-pillar Oct 4, 2026
BioMarin Pharmaceutical Inc. (BMRN) Same industry, near in market value$57.18 Oct 2, 2026$11.1B65 5-pillar Oct 4, 2026

Only 5-pillar scores are ranked together. Other models are not directly comparable. Price and score dates are shown separately; market-value dates are unavailable.

Screen more Healthcare stocks

The records behind this page

Analyst targets & estimates

What analysts have on file

Price target, low to high
$300.00 – $474.00
Consensus target
$395.20
Median target
$400.00

Consensus record · Captured .

Measured against a quoted price of $322.28 (as of Oct 2, 2026).

Insider activity

Form 4 records via FMP · Of the newest 100 records, those within the last 180 days, newest dated Sep 14, 2026

Transactions
73
Identified insiders
9
Purchases
0
Sales
58
Other transactions
15

Purchases and sales use the reported transaction category. Other transactions include awards, exercises, gifts, withholding and unclassified activity; an acquisition or disposition alone is not a purchase or sale. These records do not establish intent.

What has been published about Krystal Biotech (KRYS)?

Read these with our analysis →

Krystal Biotech Healthcare Stock: Key Questions Answered

Research dated 2026-09-13; the answers below are from that research, and the full attribution is under Sources. The last 2 questions are answered from this page's own dated data, not from the research.

What is B-VEC’s role in Krystal Biotech’s business?

B-VEC is Krystal’s most advanced therapeutic candidate and the clearest program-level test of its redosable gene-therapy approach. The remaining pipeline extends that platform across inherited skin disease, cystic fibrosis, and aesthetic dermatology.

Sources (as of 2026-09-13): Business description

Is Krystal Biotech still a clinical-stage biotechnology company?

Clinical development remains central to Krystal’s identity, but its financial profile is no longer pre-revenue. The company now reports substantial revenue, operating profit, net income, and positive operating cash flow alongside continued research spending.

Sources (as of 2026-09-13): Business description; Annual revenue and net result (USD millions); Quarterly income statement (USD thousands); Operating cash flow by quarter (USD millions)

Can Krystal fund its redosable gene-therapy pipeline internally?

Current operations are generating cash while liquid resources and investments comfortably exceed debt. That combination gives Krystal room to fund research without relying on balance-sheet depletion at the recent operating pace.

Sources (as of 2026-09-13): Cash, investments and debt; Cash and investment components; Cash and short-term investments over time (USD millions); Operating cash flow by quarter (USD millions)

What do recent KRYS insider transactions show?

Recent recorded activity was dominated by sales and other transfers, with no purchases recorded. The pattern offers no affirmative buying signal, although the transactions alone do not establish why insiders sold.

Sources (as of 2026-09-13): Insider transactions, last 180 days; What the sources do not tell us

What is the KRYS stock price today?

The last price recorded on this page for Krystal Biotech, Inc. (KRYS) is $322.28, as of the Oct 2, 2026 trading session (source: Financial Modeling Prep (FMP) · quote). It is a provider snapshot, not a live exchange feed, so check a brokerage quote before you trade.

What is the KRYS price target?

The analyst consensus price target for Krystal Biotech, Inc. (KRYS) is $395.20 (range $300.00 to $474.00, median $400.00), per FMP data captured Oct 4, 2026. Targets are analyst opinions and change often; they are not a Stock Expert AI forecast.

Disclaimer: This content is for informational purposes only and does not constitute investment advice. Always do your own research and consult a financial advisor.

Research written by Codex (gpt-5.6-sol) on 2026-09-13. AI-authored analysis; source dates are shown with each answer. Editorial oversight is systemic, not page-by-page. Editorially accountable: Sedat ANAK, Founder and Editor-in-Chief.

Sources (as of 2026-09-13): Legal name; Business description; Annual revenue and net result (USD millions); Quarterly income statement (USD thousands); Operating cash flow by quarter (USD millions); Cash and short-term investments over time (USD millions)

Sources — records for every figure on this page (45 figures)

The 45 rows below are exactly the facts the evidence-backed sections of this page printed — the 10-second verdict, the MoonshotScore, price and market value, the five questions with their receipts, and the records behind this page. Known dates and sources are recorded on their own rows; an em dash or UNRECORDED tier preserves a stored observation without inventing either. The quarterly income statement is provider-standardized (FMP) under one row, and scale definitions — a 0-100 rating, the band ladder, the Piotroski 0–9 range — are fixed rather than measured. No number in those sections was generated by a model. The register does not cover quoted third-party headlines, the dated council readings, or the Frequently Asked Questions; each of those says where it came from where it stands.

"As of" is the date the value is true for where the source carries one — a quarter end, a filing date, a price close, the day the score was computed. A cached observation with no source date remains undated; the page publication date is not used as a substitute.

OFFICIAL — 1 fact from SEC filings and earnings calls

OFFICIAL facts used on this page
Fact IDFactValue as shownAs ofTierSource
id.hqSEC filing business address2100 Wharton Street, Suite 701, Pittsburgh, PA, 15203OFFICIALSEC EDGAR filer business address — The SEC filer business address. Our market-data provider separately lists "2100 Wharton Street, Pittsburgh, PA, 15203, US".

FMP — 38 facts from Financial Modeling Prep endpoint families

FMP facts used on this page
Fact IDFactValue as shownAs ofTierSource
px.lastLatest provided price$322.28FMPFinancial Modeling Prep (FMP) · quote — Dated to the US trading session the price belongs to, derived from the quote record's timestamp (weekend and pre-open reads roll back to the previous weekday; exchange holidays are not modelled). The record does not establish an exchange execution time. Retrieved 2026-10-04T10:44:33.061Z.
px.changeChange on the day-0.93%FMPFinancial Modeling Prep (FMP) · quote
px.mcapMarket capitalization$9.54BFMPFinancial Modeling Prep (FMP) quote — Provider market cap uses the share class it prices; a company with more than one class may show a larger total elsewhere. Market cap record date: 2026-10-04. Source capture time was not supplied. No share-count basis is inferred; this page preserves the reported amount instead of recalculating it from shares.
earn.nextNext earnings dateNov 2, 2026FMPFinancial Modeling Prep (FMP) earnings calendar — The date is our provider's estimate until the company confirms it.
px.change_absChange on the day, in dollars−$3.03FMPFinancial Modeling Prep (FMP) · quote
fin.q_revenueRevenue, Q2 FY2026$119MFMPFinancial Modeling Prep (FMP) · income statement (quarterly)
px.range5252-week range$179.19–$382.54FMPFinancial Modeling Prep (FMP) quote
px.pePrice / earnings (trailing)38.97FMPFinancial Modeling Prep (FMP) · quote
px.volumeShares traded on the day426.1KFMPFinancial Modeling Prep (FMP) · quote
px.betaBeta0.54FMPFinancial Modeling Prep (FMP) company profile
id.ceoChief executiveKrish S. KrishnanFMPFinancial Modeling Prep (FMP) key executives (proxy-derived) — Titles and pay come from the company's proxy statement as our provider parsed it.
id.employeesEmployees295FMPFinancial Modeling Prep (FMP) company profile
fin.annualRevenue and net result by fiscal year5 fiscal years, FY2021 through FY2025: FY2021 revenue $0.00, net result $0.00; FY2022 revenue $0.00, net result $0.00; FY2023 revenue $0.00, net result $0.00; FY2024 revenue $0.00, net result $0.00; FY2025 revenue $0.00, net result $0.00FMPFinancial Modeling Prep (FMP), from the company's 10-K income statements
fin.gross_marginGross margin (trailing twelve months)93.3%FMPFinancial Modeling Prep (FMP) key-metrics-ttm + ratios-ttm — A ratio our provider could not compute is absent rather than shown as zero.
earn.history.depth.2026-08-03.revenue_actualRevenue · reported — report date 2026-08-03$119.22MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-08-03.revenue_estimatedRevenue · estimate — report date 2026-08-03$120.93MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-08-03.eps_actualEPS · reported — report date 2026-08-03$1.7900Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-08-03.eps_estimatedEPS · estimate — report date 2026-08-03$1.7000Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-05-04.revenue_actualRevenue · reported — report date 2026-05-04$116.36MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-05-04.revenue_estimatedRevenue · estimate — report date 2026-05-04$112.11MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-05-04.eps_actualEPS · reported — report date 2026-05-04$1.8300Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-05-04.eps_estimatedEPS · estimate — report date 2026-05-04$1.4500Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-02-17.revenue_actualRevenue · reported — report date 2026-02-17$107.11MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-02-17.revenue_estimatedRevenue · estimate — report date 2026-02-17$105.35MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-02-17.eps_actualEPS · reported — report date 2026-02-17$1.7000Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-02-17.eps_estimatedEPS · estimate — report date 2026-02-17$1.6200Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2025-11-03.revenue_actualRevenue · reported — report date 2025-11-03$97.80MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2025-11-03.revenue_estimatedRevenue · estimate — report date 2025-11-03$105.30MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2025-11-03.eps_actualEPS · reported — report date 2025-11-03$2.6600Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2025-11-03.eps_estimatedEPS · estimate — report date 2025-11-03$1.1200Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
fin.q_tableQuarterly income statement4 quarters through Q2 FY2026FMPFinancial Modeling Prep (FMP) · income statement (quarterly), as filed
fin.cash_investmentsCash and short-term investments$0.00FMPFinancial Modeling Prep (FMP), from the company's balance sheet — Long-term investments are shown separately; their marketability is not established by the provider field. The cash and short-term investment balance does not establish unrestricted availability. Long-term investments are excluded and remain unclassified. Restrictions on cash and short-term investments require separate review. The market-value ratio is undefined when the reported amount is zero.
fin.total_debtTotal debt$0.00FMPFinancial Modeling Prep (FMP), from the company's balance sheet — Long-term investments are shown separately; their marketability is not established by the provider field. The cash and short-term investment balance does not establish unrestricted availability.
fin.price_to_bookPrice to book value7.00×FMPFinancial Modeling Prep (FMP) key-metrics-ttm + ratios-ttm — A ratio our provider could not compute is absent rather than shown as zero.
earn.pt_rangeAnalyst price target, low to high$300.00 – $474.00FMPFinancial Modeling Prep (FMP) · price-target consensus — Captured Oct 4, 2026 · Coverage not supplied
earn.pt_consensusConsensus analyst price target$395.20FMPFinancial Modeling Prep (FMP) · price-target consensus — Captured Oct 4, 2026 · Coverage not supplied
earn.pt_medianMedian analyst price target$400.00FMPFinancial Modeling Prep (FMP) · price-target consensus — Captured Oct 4, 2026 · Coverage not supplied
own.insidersInsider transactions via FMP73 transactions · 0 purchases, 58 sales, 15 other transactions · 9 identified insiders · of the newest 100 records, those within the last 180 days, newest dated Sep 14, 2026FMPFinancial Modeling Prep (FMP), carrying Form 4 transaction records — Purchases and sales use the reported transaction category. Other transactions include awards, exercises, gifts, withholding and unclassified activity; an acquisition or disposition alone is not a purchase or sale. These records do not establish intent.

UNRECORDED — 2 facts from stored observations whose source was not recorded

UNRECORDED facts used on this page
Fact IDFactValue as shownAs ofTierSource
earn.historyReported versus estimated, recent quartersEPS beat 7 of 8UNRECORDEDStored earnings-history observation — Captured 2026-10-04
fin.scoresDistress and quality screensAltman Z 42.52 · Piotroski F 5UNRECORDEDStored financial-scores observation — Captured 2026-10-03 · Expired observation

COMPUTED — 2 facts from our arithmetic, formula restated

COMPUTED facts used on this page
Fact IDFactValue as shownAs ofTierSource
earn.history.depth.2026-08-03.revenue_actual.comparisonLatest report · revenue vs estimateBelow estimateReport date · COMPUTEDComputed from Financial Modeling Prep (FMP) earnings — Earnings-history note — Method: compare reported revenue ($119.22M) with the recorded estimate ($120.93M) at displayed precision. Equal displayed values are in line. This compares reported results with recorded estimates, not investment returns.
earn.history.depth.2026-08-03.eps_actual.comparisonLatest report · EPS vs estimateAbove estimateReport date · COMPUTEDComputed from Financial Modeling Prep (FMP) earnings — Earnings-history note — Method: compare reported EPS ($1.7900) with the recorded estimate ($1.7000) at displayed precision. Equal displayed values are in line. This compares reported results with recorded estimates, not investment returns.

OURS — 2 facts from Stock Expert AI's own score and rank

OURS facts used on this page
Fact IDFactValue as shownAs ofTierSource
ours.moonshotMoonshotScore v297 of 100 · Exceptional · pillars 96 / 97 / 39 / 98 / 80OURSStock Expert AI MoonshotScore v2 engine
ours.moonshot_changeMoonshotScore movement98 (stored snapshot Oct 3, 2026) → 97 (current publication computed Oct 4, 2026) (-1)OURSStock Expert AI current score publication and immutable score snapshots — The current score publication is not yet represented in the immutable snapshot archive.

Fact-family notes

  1. Earnings-history note. Source series as of 2026-08-03. Dates are report dates, not fiscal period ends. Revenue is in USD; EPS is USD per share, rounded to four decimals. The earnings feed does not establish a basic, diluted or adjusted basis. Earnings-feed EPS may differ from statement EPS; the two series are not combined. Applies to Fact IDs: earn.history.depth.2026-08-03.revenue_actual, earn.history.depth.2026-08-03.revenue_estimated, earn.history.depth.2026-08-03.revenue_actual.comparison, earn.history.depth.2026-08-03.eps_actual.comparison, earn.history.depth.2026-08-03.eps_actual, earn.history.depth.2026-08-03.eps_estimated, earn.history.depth.2026-05-04.revenue_actual, earn.history.depth.2026-05-04.revenue_estimated, earn.history.depth.2026-05-04.eps_actual, earn.history.depth.2026-05-04.eps_estimated, earn.history.depth.2026-02-17.revenue_actual, earn.history.depth.2026-02-17.revenue_estimated, earn.history.depth.2026-02-17.eps_actual, earn.history.depth.2026-02-17.eps_estimated, earn.history.depth.2025-11-03.revenue_actual, earn.history.depth.2025-11-03.revenue_estimated, earn.history.depth.2025-11-03.eps_actual, earn.history.depth.2025-11-03.eps_estimated.
Published
Research standards
Methodology · Editorial policy · Corrections

Sources used for research written 2026-09-13

Historical evidence preserved with this analysis. Current figures are listed separately above.

EvidenceCaptured valueSource dateSource typeSource
Legal name
Krystal Biotech, Inc.
2026-02-17OFFICIALSEC EDGAR — 10-K filed 2026-02-17
Business description
Krystal Biotech, Inc. is a clinical-stage biotechnology company focused on developing redosable gene therapies to address severe orphan diseases across the United States. Its most advanced therapeutic candidate, beremagene geperpavec (B-VEC), is currently undergoing Phase III clinical evaluation for the treatment of dystrophic epidermolysis bullosa. The company's pipeline also includes several other promising programs: KB105 is in Phase I/II clinical trials for patients suffering from deficient autosomal recessive congenital ichthyosis; KB301 is also in Phase I/II development, aiming to ameliorate wrinkles and other signs of aging or damaged skin. Additionally, Krystal Biotech is conducting preclinical research on KB407 for cystic fibrosis and KB104 for Netherton syndrome. In its earlier discovery phase, the company is exploring candidates such as KB5xx for chronic skin conditions and multiple KB3xx programs targeting aesthetic dermatological concerns. Krystal Biotech, Inc. was established in 2015 and is based in Pittsburgh, Pennsylvania.
2026-09-13FMPFinancial Modeling Prep (FMP) company profile
Annual revenue and net result (USD millions)
Captured record · 5 entries
  • FY2025 — R&D: $58.05M, Revenue: $389.13M, Period end: 2025-12-31, Net result: $204.83M
  • FY2024 — R&D: $53.57M, Revenue: $290.52M, Period end: 2024-12-31, Net result: $89.16M
  • FY2023 — R&D: $46.43M, Revenue: $50.70M, Period end: 2023-12-31, Net result: $10.93M
  • FY2022 — R&D: $42.46M, Revenue: $0, Period end: 2022-12-31, Net result: -$139.97M
  • FY2021 — R&D: $27.88M, Revenue: $0, Period end: 2021-12-31, Net result: -$69.57M
2025-12-31FMPFinancial Modeling Prep (FMP), from the company's 10-K income statements
Quarterly income statement (USD thousands)
Captured record · 8 entries
  • Quarter ended 2026-06-30 — EPS: $1.79 per share, R&D: $14.52M, SG&A: $39.85M, EPS basic: $1.85 per share, EPS basis: diluted, Revenue: $119.22M, EPS diluted: $1.79 per share, Net result: $54.77M, Gross profit: $112.78M, Operating result: $58.42M
  • Quarter ended 2026-03-31 — EPS: $1.83 per share, R&D: $15.33M, SG&A: $41.01M, EPS basic: $1.91 per share, EPS basis: diluted, Revenue: $116.36M, EPS diluted: $1.83 per share, Net result: $55.93M, Gross profit: $110.03M, Operating result: $53.69M
  • Quarter ended 2025-12-31 — EPS: $1.7 per share, R&D: $16.20M, SG&A: $41.28M, EPS basic: $1.77 per share, EPS basis: diluted, Revenue: $107.11M, EPS diluted: $1.7 per share, Net result: $51.40M, Gross profit: $96.19M, Operating result: $44.44M
  • Quarter ended 2025-09-30 — EPS: $2.66 per share, R&D: $13.19M, SG&A: $37.58M, EPS basic: $2.74 per share, EPS basis: diluted, Revenue: $97.80M, EPS diluted: $2.66 per share, Net result: $79.36M, Gross profit: $92.14M, Operating result: $41.37M
  • Quarter ended 2025-06-30 — EPS: $1.29 per share, R&D: $14.41M, SG&A: $35.16M, EPS basic: $1.33 per share, EPS basis: diluted, Revenue: $96.04M, EPS diluted: $1.29 per share, Net result: $38.33M, Gross profit: $88.88M, Operating result: $39.31M
  • Quarter ended 2025-03-31 — EPS: $1.2 per share, R&D: $14.26M, SG&A: $32.72M, EPS basic: $1.24 per share, EPS basis: diluted, Revenue: $88.18M, EPS diluted: $1.2 per share, Net result: $35.73M, Gross profit: $83.16M, Operating result: $36.18M
  • Quarter ended 2024-12-31 — EPS: $1.52 per share, R&D: $13.52M, SG&A: $31.29M, EPS basic: $1.58 per share, EPS basis: diluted, Revenue: $91.14M, EPS diluted: $1.52 per share, Net result: $45.48M, Gross profit: $86.19M, Operating result: $41.38M
  • Quarter ended 2024-09-30 — EPS: $0.91 per share, R&D: $13.51M, SG&A: $28.71M, EPS basic: $0.95 per share, EPS basis: diluted, Revenue: $83.84M, EPS diluted: $0.91 per share, Net result: $27.18M, Gross profit: $77.16M, Operating result: $22.43M
2026-06-30FMPFinancial Modeling Prep (FMP), from the company's 10-Q and 10-K income statements
Operating cash flow by quarter (USD millions)
Captured record · 8 entries
  • Quarter ended 2026-06-30 — Capital expenditure: -$3.56M, Operating cash flow: $74.79M
  • Quarter ended 2026-03-31 — Capital expenditure: -$7.15M, Operating cash flow: $80.38M
  • Quarter ended 2025-12-31 — Capital expenditure: -$2.14M, Operating cash flow: $77.51M
  • Quarter ended 2025-09-30 — Capital expenditure: -$1.70M, Operating cash flow: $39.66M
  • Quarter ended 2025-06-30 — Capital expenditure: -$1.90M, Operating cash flow: $52.73M
  • Quarter ended 2025-03-31 — Capital expenditure: -$6.20M, Operating cash flow: $30.97M
  • Quarter ended 2024-12-31 — Capital expenditure: -$800,000, Operating cash flow: $52.84M
  • Quarter ended 2024-09-30 — Capital expenditure: -$1.05M, Operating cash flow: $58.86M
2026-06-30FMPFinancial Modeling Prep (FMP), from the company's 10-Q cash-flow statements
Cash and short-term investments over time (USD millions)
Captured record · 8 entries
  • 2026-06-30 — Amount: $845.60M, Cash basis: cash and short-term investments
  • 2026-03-31 — Amount: $823.40M, Cash basis: cash and short-term investments
  • 2025-12-31 — Amount: $827.80M, Cash basis: cash and short-term investments
  • 2025-09-30 — Amount: $731.10M, Cash basis: cash and short-term investments
  • 2025-06-30 — Amount: $682.00M, Cash basis: cash and short-term investments
  • 2025-03-31 — Amount: $616.80M, Cash basis: cash and short-term investments
  • 2024-12-31 — Amount: $597.50M, Cash basis: cash and short-term investments
  • 2024-09-30 — Amount: $588.30M, Cash basis: cash and short-term investments
2026-06-30FMPFinancial Modeling Prep (FMP), from the company's quarterly balance sheets
Sector / industry (provider taxonomy)
Healthcare / Biotechnology

The company's SEC filings classify it under SIC 2836 — Biological Products, (No Diagnostic Substances).

2026-09-13FMPFinancial Modeling Prep (FMP) company profile
Cash, investments and debt
Total debt: $8.85M; Liquidity basis: cash and short-term investments; Total liabilities: $141.52M; Cash and short-term investments: $845.63M; Cash and investments: $1.10B; Long-term investments: $257.29M; Long-term investments classification: unclassified

Long-term investments are shown separately; their marketability is not established by the provider field. The cash and short-term investment balance does not establish unrestricted availability.

2026-06-30FMPFinancial Modeling Prep (FMP), from the company's balance sheet
Cash and investment components
Total basis: cash short and long-term investments; Total: $1.10B; Cash and short-term investments: $845.60M; Long-term investments: $257.30M; Long-term investments classification: unclassified

Sums the balance sheet's cash and short-term investments with its long-term investments.; The long-term investment field does not establish marketability; the sum is not a measure of available liquidity.; These provider fields do not establish investment access restrictions or explain differences from third-party cash figures.

2026-06-30COMPUTEDComputed from the balance sheet
Next earnings report
Date: 2026-11-02; EPS estimate: $1.91 per share; Revenue estimate: $129.65M

The date is our provider's estimate until the company confirms it.

2026-09-13FMPFinancial Modeling Prep (FMP) earnings calendar
Insider transactions, last 180 days
Net shares: -129,691; Window days: 180; Price low: $179.25; Price high: $366.56; Buy transactions: 0; Distinct insiders: 4; Sell transactions: 57; Other transactions: 3; Total transactions: 60; Other transaction types: G-Gift: 1, M-Exempt: 2; Unknown direction transactions: 0

Purchase and sale counts require explicit provider transaction types, without a conflicting acquisition/disposition direction. Other transactions retain their provider type; awards, exercises, gifts and in-kind transactions are not counted as purchases or sales. Net shares sums acquired minus disposed shares across direction-known records, including other transaction types; unknown directions are excluded. It is not net purchases or a verified change in beneficial ownership. Named-insider counts, same-day clusters and positive reported prices cover all retained records. Filing dates are used only when transaction dates are absent. Neither timing nor price establishes motive or whether a transaction was on the open market.

2026-09-04FMPFinancial Modeling Prep (FMP) insider transactions, from Form 4 filings
What the sources do not tell us
Captured record · 3 entries
  • What: We hold fewer than two daily score snapshots for this company, so there is no track to show yet., Family: Score history
  • What: A Form 4 records what an insider transacted, never why. Sales that look like tax withholding on vesting shares are not labelled as such in the filing., Family: Insider intent
  • What: Anything that changed after the most recent filing and has not been announced is not on this page., Family: Between filings

Each entry names a family of information the packet has no fact for.; The list is drawn from a fixed catalogue keyed to fact ids — it is not written per ticker and contains no generated text.; An absent family means our sources did not answer; it does not mean the company has nothing to report.

2026-09-13COMPUTEDDerived from which sources answered this build
Data Sources & Methodology
Figures come from Financial Modeling Prep (FMP). If FMP has no figure for a ticker, a price or fundamental may come from a Yahoo Finance fallback, or a price from an Alpaca fallback. SEC EDGAR is used only for filing links and company identity details (legal name, address), never for figures. AI analysis by Stock Expert AI proprietary algorithms. Technical indicators via industry-standard calculations. Last updated: .
Data Provenance
Sources: Financial Modeling Prep (FMP) — Primary · Yahoo Finance — Fallback · Alpaca — Tertiary
Last fetched:
Cache TTL: Quote 5min · Profile 7d · Financials 7d · Insider 48h
How we use AI: Numbers are pulled directly from FMP & Yahoo Finance — our AI writes the analysis, it never edits the figures.
Data provided as-is for educational purposes. Not financial advice. Methodology

Data provided for informational purposes only.

ETFs that hold KRYS

Funds in our ETF coverage that list KRYS among the top 10 holdings on their fund page, largest weight first. Each weight is the fund's reported holding weight as of the date in its row.

ETFWeightHoldings as of
iShares Russell 2000 ETF (IWM)0.30%