Invesco Biotechnology & Genome ETF (PBE) Fund Overview
Educational signal · not a buy or sell recommendation · How to read this
Beta 1.07: the stock has moved about 7% more than the S&P 500.
For informational purposes only. Not financial advice. Machine-generated analysis by Stock Expert AI — model gemini-2.0-flash, generated Mar 18, 2026. Editorial oversight is systemic, not page-by-page. Editorially accountable: Sedat ANAK, Founder and Editor-in-Chief. Data sources: Financial Modeling Prep, Yahoo Finance, SEC EDGAR
Quick AnswerInvesco Biotechnology & Genome ETF (PBE) trades at $94.89. The Invesco Biotechnology & Genome ETF (PBE) aims to provide capital appreciation by investing in US biotechnology and genome companies. Sector: Financials.
Price as of · Last analyzed: Mar 18, 2026Analyst Coverage for PBE: PBE does not currently have published analyst price targets in our coverage universe. This is common for smaller-cap names with limited Wall Street coverage.
Invesco Biotechnology & Genome ETF (PBE) Financial Services Profile
Invesco Biotechnology & Genome ETF (PBE) seeks capital appreciation by investing in a portfolio of approximately 30 U.S. biotechnology and genome companies, tracking the Dynamic Biotech & Genome Intellidex Index, which uses investment merit criteria like price and earnings momentum, quality, management action, and value.
What Is the Investment Thesis for PBE?
The Invesco Biotechnology & Genome ETF (PBE), with a market capitalization of $0.26 billion and a beta of 1.07, presents a targeted investment vehicle for exposure to the biotechnology and genome sectors. The fund's strategy of tracking the Dynamic Biotech & Genome Intellidex Index, which selects companies based on factors like price and earnings momentum, aims to capture capital appreciation. The quarterly rebalancing schedule ensures the portfolio remains aligned with current market conditions. A key consideration is the absence of dividend yield, making it less attractive for income-focused investors. Growth is tied to the performance of the underlying biotechnology and genome companies, influenced by factors such as regulatory approvals, clinical trial outcomes, and technological advancements. Investors should monitor the performance of the index and the overall health of the biotechnology and genome industries.
Based on FMP financials and quantitative analysis
PBE Key Highlights
Market Cap of $0.26B indicates a mid-sized ETF within the biotechnology and genome sector.
- Beta of 1.07 suggests the ETF's price is slightly more volatile than the overall market.
- The ETF invests at least 90% of its assets in securities comprising the Dynamic Biotech & Genome Intellidex Index.
- Quarterly rebalancing in February, May, August, and November ensures the portfolio remains aligned with the index's criteria.
- Absence of dividend yield may make it less attractive for income-focused investors.
Who Are PBE's Competitors?
PBE is benchmarked below against 8 industry peers on price, market cap, and our AI MoonshotScore.
| Company | Price | Change | Market Cap | MoonshotScore |
|---|---|---|---|---|
| AVSD Avantis Responsible International Equity ETF | $79.55 | +0.00% | $346M | — |
| CLSE Convergence Long/Short Equity ETF | $34.42 | +0.50% | $396M | — |
| DEXC Dimensional - Emerging Markets ex China Core Equity ETF | $82.56 | +1.06% | $367M | — |
| EDOW First Trust Dow 30 Equal Weight ETF | $44.44 | +0.05% | $236M | — |
| IQSI NYLI Candriam International Equity ETF | $38.30 | +0.22% | $259M | — |
| BLK BlackRock, Inc. | $1066.45 | +0.64% | $165B | 51 5-pillar |
| BX Blackstone Inc. | $111.64 | -0.09% | $136B | 68 5-pillar |
| APOS Apollo Global Management, Inc. | $25.59 | 0.00% | $74.8B | 56 5-pillar |
AI Score by Stock Expert AI · Price data: FMP / Yahoo Finance
What Are PBE's Key Strengths?
Exposure to high-growth biotechnology and genome sectors.
- Diversification across multiple companies reduces risk.
- Transparent index-tracking strategy.
- Quarterly rebalancing ensures portfolio alignment.
What Are PBE's Weaknesses?
Subject to volatility in the biotechnology and genome sectors.
- Absence of dividend yield may deter income-focused investors.
- Performance is dependent on the success of the underlying companies.
- Expense ratio reduces overall returns.
What Are the Key Risks for PBE?
Weak fundamentals — a Piotroski F-Score of 3/9 flags soft profitability, leverage or efficiency.
- Regulatory setbacks and clinical trial failures impacting portfolio companies.
- Market volatility and economic downturns affecting investor sentiment.
- Patent expirations and competition from generic drugs.
- Dependence on the performance of underlying biotechnology and genome companies.
What Are PBE's Competitive Advantages?
- Index-tracking strategy provides a defined and transparent investment approach.
- Diversification across multiple biotechnology and genome companies reduces risk.
- Established brand and reputation of Invesco as an asset manager.
- Quarterly rebalancing ensures the portfolio remains aligned with the index's criteria.
What Does PBE Do?
The Invesco Biotechnology & Genome ETF (PBE) is designed to provide investors with exposure to the biotechnology and genome sectors. Launched by Invesco, a well-established asset management firm, the fund operates by tracking the Dynamic Biotech & Genome Intellidex Index. This index focuses on U.S.-based companies that are principally engaged in the research, development, manufacture, and marketing of biotechnological products, services, and processes, as well as companies that benefit significantly from advances in biotechnology and genetic engineering. The ETF invests at least 90% of its total assets in the securities that comprise the Index. The Index employs a quantitative methodology, evaluating companies based on factors such as price momentum, earnings momentum, quality, management action, and value to identify those with the greatest potential for capital appreciation. The fund is rebalanced and reconstituted quarterly in February, May, August, and November, ensuring that the portfolio remains aligned with the index's criteria and reflects the latest market dynamics. PBE offers investors a way to gain diversified exposure to the biotechnology and genome sectors without having to individually select stocks, making it a convenient option for those seeking to participate in the growth of these industries.
What Products and Services Does PBE Offer?
- Invests in U.S. biotechnology and genome companies.
- Tracks the Dynamic Biotech & Genome Intellidex Index.
- Provides capital appreciation through investments.
- Rebalances and reconstitutes its portfolio quarterly.
- Focuses on companies engaged in biotechnology research, development, and manufacturing.
- Targets companies benefiting from advances in genetic engineering.
How Does PBE Make Money?
- Generates revenue through management fees charged to investors.
- Aims to outperform its benchmark index, the Dynamic Biotech & Genome Intellidex Index.
- Attracts investors seeking exposure to the biotechnology and genome sectors.
- Rebalances portfolio quarterly to maintain alignment with the index.
What Industry Does PBE Operate In?
The Invesco Biotechnology & Genome ETF (PBE) operates within the asset management industry, specifically focusing on the biotechnology and genome sectors. These sectors are characterized by high growth potential driven by advancements in genetic engineering, personalized medicine, and biopharmaceuticals. The competitive landscape includes other specialized ETFs and mutual funds that target similar segments of the market. The biotechnology industry is subject to regulatory scrutiny, clinical trial risks, and patent expirations, all of which can impact the performance of companies within the sector. PBE offers a diversified approach to investing in this dynamic and rapidly evolving industry.
Who Are PBE's Key Customers?
- Individual investors seeking exposure to the biotechnology and genome sectors.
- Institutional investors looking for diversified investment options.
- Financial advisors seeking to build portfolios for their clients.
- Retirement funds and pension plans.
Research confidence
Thin evidence — scoring coverage unknown. Treat this as a starting point, not a conclusion.
- ● Scoring coverage unknown
- ● Price is current
- ● No filing on record
- ● No analyst coverage
- ● This is an etf, not an operating company
MoonshotScore History
Recorded daily since 2026-08-23 · 42 snapshots
| 2026-08-23 | 47 |
| 2026-08-31 | 47 |
| 2026-09-08 | 47 |
| 2026-09-16 | 47 |
| 2026-09-24 | 47 |
| 2026-10-04 | 47 |
| 2026-10-05 | 47 |
What changed?
The score has stayed at 47.
Over the same 30 days the stock moved -3.0%.
Financial Health
Invesco Biotechnology & Genome ETF's Piotroski F-Score is 3/9, a 9-point checklist of profitability, leverage and efficiency — flagging fundamental weakness worth scrutiny. Its Altman Z-Score of 3.73 places it in the safe zone, indicating low near-term bankruptcy risk.
PBE Financials
Bull Case vs Bear Case
Bull Case
- Exposure to high-growth biotechnology and genome sectors.
- Diversification across multiple companies reduces risk.
- Transparent index-tracking strategy.
- Quarterly rebalancing ensures portfolio alignment.
Bear Case
- Subject to volatility in the biotechnology and genome sectors.
- Absence of dividend yield may deter income-focused investors.
- Performance is dependent on the success of the underlying companies.
- Expense ratio reduces overall returns.
AI-generated arguments based on insider flow, news sentiment and technicals — not financial advice · March 2026
PBE Latest News
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Cathie Wood Loads Up On Biotech: 5 ETFs Holding Her Latest Bets
benzinga · Sep 22, 2026
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iShares' IYH or Invesco's PBE: Which Healthcare ETF Is the Better Long-Term Buy?
fool.com · Sep 9, 2026
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Pharma ETF or Biotech ETF: Which Matches Your Investing Mindset?
fool.com · Aug 21, 2026
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Is Invesco Biotechnology & Genome ETF (PBE) a Strong ETF Right Now?
zacks.com · Aug 13, 2026
PBE Analyst Consensus
Consensus Rating
Aggregated Buy/Hold/Sell recommendations collected by Financial Modeling Prep for PBE.
Price Targets
Wall Street price target analysis for PBE.
PBE MoonshotScore
MoonshotScore is Stock Expert AI's proprietary 0-100 research rating, not a buy or sell recommendation. No MoonshotScore is published for PBE; grades run from A+ (80-100) to F (below 30).
Latest News
Cathie Wood Loads Up On Biotech: 5 ETFs Holding Her Latest Bets
iShares' IYH or Invesco's PBE: Which Healthcare ETF Is the Better Long-Term Buy?
Pharma ETF or Biotech ETF: Which Matches Your Investing Mindset?
Is Invesco Biotechnology & Genome ETF (PBE) a Strong ETF Right Now?
What Investors Ask About Invesco Biotechnology & Genome ETF (PBE) — Financials
What do analysts say about PBE stock?
Generally, ETFs are evaluated based on the performance of their underlying assets and the overall health of the sectors they track.
Disclaimer: This content is for informational purposes only and does not constitute investment advice. Always do your own research and consult a financial advisor.
Official Resources
MoonshotScore is not published for this security.
Data provided for informational purposes only.
- Data is based on publicly available information and may be subject to change.