Skip to main content
Skip to main content
CRYO logo

American CryoStem Corporation (CRYO) Stock Analysis

Educational signal · not a buy or sell recommendation · How to read this

DELISTED

What happened to American CryoStem Corporation (CRYO) stock?

American CryoStem Corporation (CRYO) no longer trades on public markets. The figures below are historical and are not a current quote.

Vol: 18.8K|
Data from FMP · Methodology

For informational purposes only. Not financial advice. Machine-generated analysis by Stock Expert AI — model gpt-4o-mini, generated Jun 14, 2026. Editorial oversight is systemic, not page-by-page. Editorially accountable: Sedat ANAK, Founder and Editor-in-Chief. Data sources: Financial Modeling Prep, Yahoo Finance, SEC EDGAR

American CryoStem Corporation (CRYO). American CryoStem Corporation specializes in developing technologies from adipose tissue for regenerative medicine. Founded in 1987, the company focuses on cryopreservation services and stem cell therapies, aiming to address niche healthcare needs. Sector: Healthcare.

Last analyzed: Jun 14, 2026
American CryoStem Corporation specializes in developing technologies from adipose tissue for regenerative medicine. Founded in 1987, the company focuses on cryopreservation services and stem cell therapies, aiming to address niche healthcare needs.

Analyst Coverage for CRYO: CRYO does not currently have published analyst price targets in our coverage universe. This is common for smaller-cap names with limited Wall Street coverage. In the absence of analyst consensus, our AI model evaluates CRYO against Healthcare peers across nine fundamental dimensions and assigns a neutral fundamental signal based on the underlying data.

Watch the CRYO film Every key number, told as a short cinematic story — just press play. ~2 min
Council Score · Weighted Average of 3 Disciplines
Split View 40/100 · C

CRYO: 1/2 scored disciplines lean bearish. Dominant signal: Ken Griffin bearish.

How is this calculated? →
Legends Council · 5 Legends + Moon AI

AI simulations built from the named investors' published principles. Not affiliated with, endorsed by, or the opinion of these individuals. How these lenses are built

Dalio-style lens (simulated)Ray Dalio
Favorable read
Griffin-style lens (simulated)Ken Griffin
Unfavorable read
Simons-style lens (simulated)Jim Simons
Neutral read
Englander-style lens (simulated)Izzy Englander
Neutral read
Klarman-style lens (simulated)Seth Klarman
Unfavorable read
Moon AI lens (model)
Neutral read
Munger's Mindset · Balance Sheet & Valuation
Financial Health
Weak
Margin of Safety
Fairly Valued
Council Score · Weighted Average of 3 Disciplines · See tabs for details →
The lenses are modelled on the published principles of the investors named. We are not affiliated with them, they have not endorsed this, and it is not their opinion of this stock.

American CryoStem Corporation (CRYO) Healthcare & Pipeline Overview

CEOJohn S. Arnone
Employees4
HeadquartersEatontown, US
IPO Year2010

American CryoStem Corporation (CRYO) is a biotechnology firm dedicated to advancing regenerative medicine through innovative adipose-derived technologies, including tissue preservation and stem cell therapies, positioning itself as a niche player in a rapidly evolving healthcare landscape.

Data Provenance | Financial Data Quantitative Analysis Analysis: Jun 14, 2026

What Is the Investment Thesis for CRYO?

AI-written as of Jun 14, 2026 — figures and tone reflect the data available then, not today's score.

American CryoStem Corporation is positioned to capitalize on the growing demand for regenerative medicine solutions, particularly in the area of adipose-derived therapies. The company's unique offerings, including the CELLECT system and ATGRAFT service, provide a competitive edge by streamlining tissue processing and enhancing clinical outcomes. However, the company faces challenges such as a negative profit margin of -13985.4%, which highlights the need for improved operational efficiency and revenue generation. As the market evolves, American CryoStem's ability to secure funding and navigate regulatory hurdles will be crucial for its sustained growth and success.

Based on FMP financials and quantitative analysis

CRYO Key Highlights

AI-written as of Jun 14, 2026 — figures and tone reflect the data available then, not today's score.

Market Cap of $0.00B indicates a micro-cap status, potentially appealing to niche investors.

  • Profit Margin of -13985.4% reflects significant operational challenges that need addressing.
  • Gross Margin of 34.1% suggests potential for profitability if revenue can be increased.
  • Beta of 11.42 indicates high volatility, which may attract risk-tolerant investors.
  • No dividend yield signifies a focus on reinvestment rather than returning capital to shareholders.

Who Are CRYO's Competitors?

CRYO is benchmarked below against 8 industry peers on price, market cap, and our AI MoonshotScore.

Company Price Change Market Cap MoonshotScore
CGEN Compugen Ltd. $2.47 +0.41% $234M
RLYB Rallybio Corporation $16.75 -1.30% $88.9M 825-pillar
ICCC ImmuCell Corporation $9.91 +0.05% $89.7M 775-pillar
ORMP Oramed Pharmaceuticals Inc. $4.74 -0.38% $194M 785-pillar
NAGE Niagen Bioscience Inc $3.04 -0.49% $242M 665-pillar
QTTB Q32 Bio Inc. $10.93 +1.96% $325M 685-pillar
NWPHF Newron Pharmaceuticals S.p.A. $20.00 0.00% $416M 689-signal
CRMD CorMedix Inc. $7.96 -0.06% $624M 885-pillar

AI Score by Stock Expert AI · Price data: FMP / Yahoo Finance This table mixes two scoring engines — compare a number only with others carrying the same tag.

What Are CRYO's Key Strengths?

Established expertise in adipose-derived technologies.

  • Innovative product offerings that address niche market needs.
  • Strong potential for growth in the expanding regenerative medicine sector.

What Are CRYO's Weaknesses?

Negative profit margin indicating operational challenges.

  • Limited workforce of only 4 employees may hinder scalability.
  • Dependence on niche market may limit revenue diversification.

What Could Drive CRYO Stock Higher?

Increased adoption of CELLECT and ATGRAFT services as awareness of adipose-derived therapies grows.

  • Development of proprietary products like ATCELL and ACSelerat that cater to the regenerative medicine market.
  • Potential partnerships with healthcare providers to expand service offerings and market reach.

What Are the Key Risks for CRYO?

Financial-distress signal — its Altman Z-Score of -41.21 sits in the distress zone (elevated bankruptcy risk).

  • Weak fundamentals — a Piotroski F-Score of 3/9 flags soft profitability, leverage or efficiency.
  • Insider selling — insiders were net sellers of roughly $6.6M recently.
  • Regulatory challenges in the biotechnology sector may impact product development timelines.
  • High volatility in stock price could deter institutional investment.
  • Limited workforce may restrict operational scalability and growth.

What Are the Growth Opportunities for CRYO?

  • American CryoStem's focus on adipose-derived therapies positions it well to capture a significant share of this expanding market, particularly as more physicians adopt these innovative solutions in clinical practice.
  • Growth opportunity 2: The CELLECT system enhances tissue sample collection and storage efficiency, addressing a critical need in regenerative medicine. As healthcare providers increasingly seek streamlined processes to improve patient outcomes, the adoption of CELLECT could lead to increased sales and market penetration, particularly in hospitals and specialized clinics.
  • Growth opportunity 3: The ATGRAFT service offers comprehensive solutions for harvesting and preserving adipose tissue, appealing to a growing number of practitioners in regenerative medicine. With the increasing demand for personalized medical treatments, this service could see substantial growth as more healthcare providers recognize the value of adipose-derived products in their practices.
  • Growth opportunity 4: American CryoStem's proprietary ATCELL product line, featuring adipose-derived stem cells, is positioned to benefit from the rising interest in stem cell therapies. As research continues to validate the efficacy of these treatments, demand for ATCELL could increase, providing a significant revenue stream for the company.
  • Growth opportunity 5: The contract manufacturing services offered by American CryoStem, including the development of specialized formulations like Autokine-CM, present an opportunity to diversify revenue streams. As the market for customized healthcare products expands, the ability to provide tailored solutions could enhance the company's competitive position and drive growth.

What Are CRYO's Competitive Advantages?

  • Specialization in adipose-derived technologies differentiates American CryoStem from competitors.
  • Proprietary products like CELLECT and ATGRAFT create barriers to entry for new entrants.
  • Strong focus on innovation and quality enhances brand reputation in the healthcare sector.

What Does CRYO Do?

Founded in 1987, American CryoStem Corporation (ACSC) is headquartered in Eatontown, New Jersey, and has established itself as a leader in the biotechnology sector, focusing on the development, commercialization, and licensing of technologies derived from adipose (fat) tissue. The company’s flagship offering, the CELLECT system, is designed to optimize the collection, transportation, and storage of tissue samples, thereby streamlining processes for medical practitioners. In addition to CELLECT, ACSC provides the ATGRAFT service, which facilitates the harvesting, processing, and preservation of adipose tissue, empowering physicians to offer diverse options for tissue products and cellular banking to their patients. The ATCELL product line features proprietary adipose-derived stem cells, while the ACSelerat cell culture media is specifically engineered to enhance the growth of human stromal cells. Furthermore, American CryoStem extends its capabilities through contract manufacturing services, producing specialized formulations such as Autokine-CM, an anti-aging topical product, and a unique range of autologous skincare solutions. The company’s commitment to innovation and quality positions it well within the regenerative medicine market, which is experiencing significant growth as interest in stem cell therapies continues to rise.

What Products and Services Does CRYO Offer?

  • Develops and commercializes technologies derived from adipose tissue.
  • Offers the CELLECT system for efficient tissue sample collection and storage.
  • Provides the ATGRAFT service for harvesting and preserving adipose tissue.
  • Markets proprietary adipose-derived stem cells under the ATCELL brand.
  • Produces ACSelerat cell culture media to support human stromal cell growth.
  • Offers contract manufacturing services for specialized healthcare formulations.

How Does CRYO Make Money?

  • Generates revenue through the sale of proprietary products and services in regenerative medicine.
  • Provides contract manufacturing services to other healthcare companies.
  • Licenses technology related to adipose-derived therapies and products.

What Industry Does CRYO Operate In?

The biotechnology industry is characterized by rapid innovation and significant investment in research and development, particularly in regenerative medicine. The global market for stem cell therapy is expected to grow at a CAGR of over 10% from 2021 to 2028, driven by advancements in technology and increasing prevalence of chronic diseases. American CryoStem operates within this dynamic landscape, focusing on adipose-derived technologies, which are gaining traction due to their versatility and potential for personalized medicine. The competitive landscape includes various players, but American CryoStem's specialized focus on adipose tissue positions it uniquely among broader biotechnology firms.

Who Are CRYO's Key Customers?

  • Healthcare providers including hospitals and clinics specializing in regenerative medicine.
  • Physicians offering personalized medical treatments utilizing adipose-derived products.
  • Research institutions conducting studies on stem cell therapies and regenerative medicine.
Model self-rating on this text: 65% (not a measure of the evidence) Updated: Jun 14, 2026

Research confidence

Low 12/100

Thin evidence — scoring coverage unknown. Treat this as a starting point, not a conclusion.

  • Scoring coverage unknown
  • Price 5 days old
  • No filing on record
  • No analyst coverage

MoonshotScore History

Recorded daily since 2026-08-23 · 4 snapshots

2026-08-23 46
2026-08-24 46
2026-08-25 46
2026-08-26 46

What changed?

The score has stayed at 46.

Over the same 3 days the stock moved +0.0%.

Net selling

Insider Activity

The most recent 8 insider filings for American CryoStem Corporation break down as 6 sales and 2 purchases. On net that is roughly 3.6M shares disposed (about $6.6M), a signal worth weighing alongside the fundamentals.

ROE 254%

Key Financial Metrics

Return on equity for American CryoStem Corporation stands at 253.8%, a gauge of how efficiently it converts shareholder capital into profit. A current ratio of 0.12 means current liabilities exceed short-term assets, a liquidity point worth watching.

F-Score 3/9

Financial Health

American CryoStem Corporation's Piotroski F-Score is 3/9, a 9-point checklist of profitability, leverage and efficiency — flagging fundamental weakness worth scrutiny. Its Altman Z-Score of -41.21 places it in the distress zone, a signal of elevated financial risk.

Company Profile

American CryoStem Corporation operates in the Biotechnology industry within the Healthcare sector. It is headquartered in Eatontown, US. The company is led by CEO John S. Arnone. CRYO has traded publicly since 2010.

CRYO Financials

Fundamental Snapshot

Return on Equity (TTM)
+253.8%
Current Ratio
0.1

Based on FMP financials and quantitative analysis

Bull Case vs Bear Case

Bull Case

  • Established expertise in adipose-derived technologies.
  • Innovative product offerings that address niche market needs.
  • Strong potential for growth in the expanding regenerative medicine sector.
  • Upcoming: Increased adoption of CELLECT and ATGRAFT services as awareness of adipose-derived therapies grows.

Bear Case

  • Negative profit margin indicating operational challenges.
  • Limited workforce of only 4 employees may hinder scalability.
  • Dependence on niche market may limit revenue diversification.
  • Ongoing: Regulatory challenges in the biotechnology sector may impact product development timelines.

AI-generated arguments based on insider flow, news sentiment and technicals — not financial advice · June 2026

CRYO Latest News

Leadership: John S. Arnone

CEO

John S. Arnone has been at the helm of American CryoStem Corporation since its inception in 1987. With a strong background in biotechnology and healthcare, he has guided the company through its development and commercialization phases. His leadership has been instrumental in establishing ACSC's focus on adipose-derived technologies and regenerative medicine.

Track Record: Under John S. Arnone's leadership, American CryoStem has developed key products such as the CELLECT system and ATGRAFT service, positioning the company as a niche player in the biotechnology sector. His strategic vision has enabled ACSC to navigate challenges and capitalize on emerging trends in regenerative medicine.

CRYO OTC Market Information

The OTC Other tier represents companies that trade on over-the-counter markets but do not meet the listing requirements of major exchanges like NYSE or NASDAQ. This tier often includes smaller, less liquid companies, which may have less stringent reporting and regulatory requirements.

  • OTC Tier: OTC Other
Liquidity: Trading volume may be low, leading to wider bid-ask spreads and potential difficulty in executing trades. Investors should be aware of the liquidity challenges associated with OTC stocks.
OTC Risk Factors:
  • Limited financial disclosures may hinder transparency for investors.
  • Potential for higher volatility and less liquidity compared to listed stocks.
  • Regulatory scrutiny may increase as the company grows, impacting operations.
Due Diligence Checklist:
  • Review recent financial statements and disclosures for accuracy.
  • Assess the company's compliance with OTC reporting requirements.
  • Evaluate the competitive landscape and market position.
  • Monitor regulatory developments affecting the biotechnology sector.
  • Investigate the management team's track record and experience.
Legitimacy Signals:
  • Established history since 1987 demonstrates longevity in the market.
  • Innovative product offerings indicate a commitment to research and development.
  • Partnerships or collaborations with reputable healthcare providers can enhance credibility.

American CryoStem Corporation Healthcare Stock: Key Questions Answered

What happened to American CryoStem Corporation (CRYO) stock?

American CryoStem Corporation (CRYO) no longer trades on public markets. The figures below are historical and are not a current quote.

Can I still buy CRYO shares?

No. CRYO stopped trading on public markets, so the shares are not available through a broker. Anything you see quoted for CRYO elsewhere is historical data, not a live market.

Are the figures on this page current?

No. Every number here is the last value recorded before CRYO stopped trading. Nothing on this page updates, and none of it is a current quote.

Why does this page still exist?

Because people still search for what happened to American CryoStem Corporation. An archived profile that states the delisting plainly is more useful than a dead link — provided it is labelled as history, which is what this page does.

What does American CryoStem Corporation do?

American CryoStem Corporation specializes in the development and commercialization of technologies derived from adipose tissue for applications in regenerative and personalized medicine.

What are the main risks for CRYO?

American CryoStem faces several risks, including regulatory challenges that could impact product development and operational timelines. Additionally, the company's negative profit margin indicates financial instability, which may affect its ability to secure funding.

What revenue streams does American CryoStem Corporation have in healthcare?

American CryoStem Corporation generates revenue through multiple streams, including the sale of proprietary products like the CELLECT system and ATGRAFT service, which cater to healthcare providers in regenerative medicine.

Disclaimer: This content is for informational purposes only and does not constitute investment advice. Always do your own research and consult a financial advisor.

Official Resources

Analysis updated
Data Sources & Methodology
Market data powered by Financial Modeling Prep & Yahoo Finance. AI analysis by Stock Expert AI proprietary algorithms. Technical indicators via industry-standard calculations. Last updated: .
Data Provenance
Sources: Financial Modeling Prep (FMP) — Primary · Yahoo Finance — Fallback · Alpaca — Tertiary
Last fetched:
Cache TTL: Quote 5min · Profile 7d · Financials 7d · Insider 48h
How we use AI: Numbers are pulled directly from FMP & Yahoo Finance — our AI writes the analysis, it never edits the figures.
Data provided as-is for educational purposes. Not financial advice. Methodology

Data provided for informational purposes only.

Analysis Notes
  • Financial data may be limited due to OTC classification and disclosure status.
Data Sources
Financial Modeling Prep (FMP)Stock Expert AI proprietary analysis

More Stocks We Cover