Cardiol Therapeutics Inc. (CRDL)
Cardiol Therapeutics Inc. is a clinical-stage life sciences company dedicated to developing innovative anti-fibrotic and anti-inflammatory therapies for cardiovascular disease. Their lead product, CardiolRx, is currently in Phase II/III clinical trials, targeting significant unmet needs in COVID-19 related cardiovascular complications and acute myocarditis.
Company Overview
Cardiol Therapeutics pioneers novel therapies for cardiovascular disease, focusing on anti-fibrotic and anti-inflammatory solutions. With CardiolRx in Phase II/III trials targeting COVID-19 related complications and myocarditis, CRDL offers a compelling investment opportunity in a high-growth sector, driven by innovative science and unmet medical needs.
Investment Thesis
Cardiol Therapeutics presents a compelling investment opportunity due to its focus on addressing significant unmet needs in cardiovascular disease with its innovative CardiolRx therapy. The ongoing Phase II/III clinical trials for COVID-19 related cardiovascular complications and acute myocarditis represent near-term catalysts. Positive trial results could lead to accelerated regulatory approval and commercialization. Furthermore, the development of a subcutaneous formulation of CardiolRx for heart failure offers long-term growth potential. With a market capitalization of $0.10 billion and a beta of 0.69, Cardiol Therapeutics offers a potentially attractive risk-reward profile for investors seeking exposure to the high-growth cardiovascular therapeutics market. The company's commitment to addressing fibrosis and inflammation in the heart positions it favorably in a market with substantial commercial opportunities.
Key Highlights
- CardiolRx is in Phase II/III clinical trials targeting COVID-19 related cardiovascular complications and acute myocarditis, addressing significant unmet medical needs.
- Developing a subcutaneous formulation of CardiolRx for the treatment of fibrosis and inflammation in the heart, which are key factors in the progression of heart failure.
- Market capitalization of $0.10 billion provides potential for significant upside if clinical trials are successful.
- Beta of 0.69 suggests lower volatility compared to the overall market, potentially offering a more stable investment.
- Focus on anti-fibrotic and anti-inflammatory therapies aligns with growing understanding of CVD pathology.
Competitors
Strengths
- Lead product CardiolRx in Phase II/III clinical trials.
- Focus on high-growth cardiovascular therapeutics market.
- Developing subcutaneous formulation for heart failure.
- Experienced management team.
Weaknesses
- Clinical-stage company with no currently approved products.
- Reliance on successful clinical trial outcomes.
- Limited financial resources.
- Small number of employees.
Catalysts
- Upcoming: Completion of Phase II/III clinical trials for CardiolRx in COVID-19 patients (2026).
- Upcoming: Announcement of clinical trial results for CardiolRx in acute myocarditis (2026).
- Ongoing: Development progress of subcutaneous CardiolRx formulation for heart failure.
- Ongoing: Potential for partnerships and licensing agreements.
Risks
- Potential: Unsuccessful clinical trial outcomes for CardiolRx.
- Potential: Regulatory delays or rejection of CardiolRx.
- Ongoing: Competition from established pharmaceutical companies with greater resources.
- Ongoing: Dependence on securing additional funding to support clinical trials and operations.
- Potential: Negative impact from changes in healthcare policies.
Growth Opportunities
- Expansion of CardiolRx into COVID-19 Related Cardiovascular Complications: The global market for treating cardiovascular complications arising from COVID-19 is substantial and growing. Positive Phase II/III trial results could lead to rapid regulatory approval and commercialization, providing a significant revenue stream for Cardiol Therapeutics. This represents a near-term growth opportunity with a potential market size in the billions.
- CardiolRx for Acute Myocarditis: Acute myocarditis, an inflammatory condition of the heart, represents another significant market opportunity for CardiolRx. Successful clinical trials could position CardiolRx as a leading therapy for this condition, addressing a critical unmet need. The market for myocarditis treatment is expected to grow as diagnostic capabilities improve, leading to increased detection rates.
- Subcutaneous Formulation for Heart Failure: The development of a subcutaneous formulation of CardiolRx targeting fibrosis and inflammation in the heart offers a long-term growth opportunity in the heart failure market. Heart failure is a leading cause of hospitalization and death, creating a substantial market for effective therapies. This formulation could provide a more convenient and effective treatment option for patients, driving adoption and revenue growth.
- Partnerships and Licensing Agreements: Cardiol Therapeutics can pursue partnerships and licensing agreements with larger pharmaceutical companies to accelerate the development and commercialization of CardiolRx. These partnerships could provide access to additional resources, expertise, and distribution networks, enhancing the company's growth prospects and market reach.
- Expansion into New Cardiovascular Indications: Cardiol Therapeutics can leverage its expertise in anti-fibrotic and anti-inflammatory therapies to expand into new cardiovascular indications beyond COVID-19 complications, myocarditis and heart failure. This could include developing therapies for other fibrotic heart conditions, such as hypertrophic cardiomyopathy or atrial fibrillation, further diversifying the company's product pipeline and revenue streams.
Opportunities
- Positive clinical trial results leading to regulatory approval.
- Partnerships and licensing agreements with larger pharmaceutical companies.
- Expansion into new cardiovascular indications.
- Growing market for cardiovascular therapeutics.
Threats
- Unsuccessful clinical trial outcomes.
- Competition from established pharmaceutical companies.
- Regulatory hurdles and delays.
- Changes in healthcare policies.
Competitive Advantages
- Proprietary CardiolRx formulation with patent protection.
- Clinical trial data demonstrating efficacy and safety.
- Expertise in anti-fibrotic and anti-inflammatory therapies.
- Focus on unmet needs in cardiovascular disease.
About
Cardiol Therapeutics Inc., established in 2017 and headquartered in Oakville, Canada, is a clinical-stage life sciences company focused on the research and development of innovative therapies for cardiovascular disease (CVD). Recognizing the significant unmet needs in treating heart conditions, Cardiol Therapeutics is dedicated to developing anti-fibrotic and anti-inflammatory therapies. The company's lead product, CardiolRx, is a pharmaceutically produced cannabidiol formulation currently undergoing a Phase II/III multi-national, randomized, double-blind, and placebo-controlled clinical trial. This trial aims to evaluate the efficacy and safety of CardiolRx in reducing cardiovascular and respiratory events in patients hospitalized with COVID-19. Furthermore, CardiolRx is being investigated for its potential in treating acute myocarditis, an inflammatory condition of the heart. Beyond its current clinical trials, Cardiol Therapeutics is also developing a subcutaneous formulation of CardiolRx. This formulation is designed to target fibrosis and inflammation in the heart, which are key factors in the development and progression of heart failure. By focusing on these critical areas, Cardiol Therapeutics aims to provide innovative solutions for patients suffering from CVD.
What They Do
- Researches and develops anti-fibrotic therapies for cardiovascular disease.
- Develops anti-inflammatory therapies for cardiovascular disease.
- Conducts clinical trials to evaluate the efficacy and safety of CardiolRx.
- Focuses on treating cardiovascular complications related to COVID-19.
- Develops therapies for acute myocarditis.
- Creates subcutaneous formulations of CardiolRx for heart failure treatment.
Business Model
- Develops and patents novel pharmaceutical therapies.
- Conducts clinical trials to demonstrate safety and efficacy.
- Seeks regulatory approval for commercialization.
- Potential for out-licensing or direct sales of approved therapies.
Industry Context
Cardiol Therapeutics operates in the specialty and generic drug manufacturing industry within the broader healthcare sector. The cardiovascular therapeutics market is experiencing growth driven by an aging population and increasing prevalence of CVD. Competition includes companies like ASRT, CNTB, HYPR, IFRX, and IMA, but Cardiol differentiates itself through its focus on anti-fibrotic and anti-inflammatory therapies using CardiolRx. The company's focus on innovative therapies positions it to capitalize on the growing demand for effective CVD treatments.
Key Customers
- Hospitals and healthcare providers treating cardiovascular disease.
- Patients suffering from cardiovascular complications related to COVID-19.
- Patients diagnosed with acute myocarditis.
- Patients with heart failure.
Financials
Chart & Info
Price Chart
Cardiol Therapeutics Inc. (CRDL) stock price: $1.00 (+0.01, +0.58%)
Why Bull
- •Recent insider buying suggests confidence in Cardiol's pipeline, indicating a belief in upcoming breakthroughs.
- •Community sentiment has shifted positively as recent trial updates hint at potential advancements in heart disease treatments.
- •Increased media coverage has highlighted Cardiol's innovative approaches, attracting attention from both investors and healthcare professionals.
- •Partnership discussions with larger pharmaceutical companies have sparked optimism about future collaborations and resource support.
Why Bear
- •Concerns about regulatory hurdles have surfaced, as the approval process for new therapies can be lengthy and unpredictable.
- •Market perception remains cautious due to the competitive landscape in the cardiovascular sector, with many players vying for attention.
- •Some community members express skepticism regarding the scalability of Cardiol's technology, fearing it may not translate to widespread clinical use.
- •Recent volatility in biotech stocks has led to a risk-averse sentiment, causing traders to be wary of investing in smaller firms like Cardiol.
Latest News
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HC Wainwright & Co. Reiterates Buy on Cardiol Therapeutics, Maintains $9 Price Target
benzinga · Feb 10, 2026
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Cardiol Therapeutics Announces Publication Of Results From Phase II ARCHER Study In ESC Heart Failure, Journal Of European Society Of Cardiology
benzinga · Feb 10, 2026
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Cardiol Therapeutics' ARCHER Phase II Study Results Published in ESC Heart Failure
Yahoo! Finance: CRDL News · Feb 10, 2026
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Cardiol Therapeutics' ARCHER Phase II Study Results Published in ESC Heart Failure
TMX Newsfile · Feb 10, 2026
Technical Analysis
Rationale
AI-generated technical analysis for CRDL including trend direction, momentum, and pattern recognition.
What to Watch
Key support and resistance levels, volume signals, and upcoming events.
Risk Management
Position sizing, stop-loss levels, and risk-reward assessment.
Community
Discussion
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Sentiment
Community sentiment and discussion activity for CRDL.
Make a Prediction
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Current price: $1.00
Analyst Consensus
Consensus Rating
Aggregated Buy/Hold/Sell recommendations from Benzinga, Yahoo Finance, and Finnhub for CRDL.
Price Targets
Wall Street price target analysis for CRDL.
Insider Flow (30d)
No insider trades in the last 30 days.
MoonshotScore
Score Factors
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Revenue Growth 5/100
Revenue growth data is currently unavailable for this company.
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Gross Margin 5/100
Gross margin data is currently unavailable for this company.
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Operating Leverage 4/100
Limited operating leverage due to slower revenue growth, keeping profit scaling constrained.
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Cash Runway 5/100
Cash position data is currently unavailable for this company.
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R&D Intensity 5/100
R&D spending data is currently unavailable for this company.
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Insider Activity 6/100
No significant insider buying or selling recently, which is neutral for the stock outlook.
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Short Interest 5/100
Float and volume data unavailable for liquidity analysis.
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Price Momentum 0/100
No bullish technical signals detected. The stock lacks upward price momentum currently.
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News Sentiment 5/100
No sentiment data available
What does this score mean?
The MoonshotScore rates CRDL's growth potential on a scale of 0-100 across multiple factors including innovation, market disruption, financial health, and momentum.
Competitors & Peers
Latest News
HC Wainwright & Co. Reiterates Buy on Cardiol Therapeutics, Maintains $9 Price Target
Cardiol Therapeutics Announces Publication Of Results From Phase II ARCHER Study In ESC Heart Failure, Journal Of European Society Of Cardiology
Cardiol Therapeutics' ARCHER Phase II Study Results Published in ESC Heart Failure
Cardiol Therapeutics' ARCHER Phase II Study Results Published in ESC Heart Failure
Frequently Asked Questions
What does Cardiol Therapeutics Inc. do?
Cardiol Therapeutics Inc. is a clinical-stage life sciences company focused on developing innovative anti-fibrotic and anti-inflammatory therapies for cardiovascular disease (CVD). Their primary focus is on CardiolRx, a pharmaceutically produced cannabidiol formulation currently in Phase II/III clinical trials. These trials are evaluating its efficacy in treating cardiovascular complications related to COVID-19 and acute myocarditis. Additionally, they are developing a subcutaneous formulation of CardiolRx to address fibrosis and inflammation in the heart, key factors in heart failure progression. The company aims to provide novel therapeutic solutions for significant unmet needs in the CVD market.
Is CRDL stock a good buy?
CRDL stock presents a speculative investment opportunity with high potential upside and significant risks. The company's future hinges on the success of its CardiolRx clinical trials. Positive results could lead to substantial gains, while negative results could significantly impact the stock price. With a market cap of $0.10 billion, CRDL offers potential for growth, but investors should carefully consider the inherent risks associated with clinical-stage pharmaceutical companies. The P/E ratio of -3.39 indicates the company is not currently profitable, further emphasizing the speculative nature of the investment. Investors should conduct thorough due diligence and assess their risk tolerance before investing.
What are the main risks for CRDL?
The primary risks for Cardiol Therapeutics revolve around the success of its clinical trials for CardiolRx. Failure to demonstrate efficacy or safety in these trials would significantly impact the company's prospects. Regulatory hurdles and potential delays in obtaining approval for CardiolRx also pose risks. Competition from larger, more established pharmaceutical companies with greater resources is another significant challenge. Additionally, the company's reliance on securing additional funding to support its operations and clinical trials creates financial risk. Changes in healthcare policies and reimbursement rates could also negatively impact the company's future revenue potential.
Is CRDL a good stock to buy?
Whether CRDL is a good investment depends on your financial goals, risk tolerance, and investment horizon. Key factors to evaluate include the company's revenue growth trajectory, profit margins, debt-to-equity ratio, competitive moat, and valuation multiples (P/E, P/S, EV/EBITDA) relative to industry peers. Our AI-generated Investment Thesis and SWOT analysis on this page provide a data-driven starting point. Always do your own research and consider consulting a financial advisor before making investment decisions.
What is the CRDL MoonshotScore?
The MoonshotScore for CRDL is an AI-powered rating from 0 to 100 that evaluates a stock across four dimensions: growth potential (revenue and earnings trajectory), financial health (balance sheet strength, cash flow), market momentum (price trends, volume patterns, institutional flows), and risk factors (volatility, debt levels, sector headwinds). Scores above 70 indicate strong potential, 50-70 moderate, and below 50 suggests caution. The score is recalculated daily using the latest financial data and market signals.
How often is CRDL data updated?
CRDL stock prices are updated in real-time during U.S. market hours (9:30 AM - 4:00 PM ET, Monday through Friday). After-hours and pre-market prices are also tracked. Company fundamentals (earnings, revenue, balance sheet) are refreshed when new quarterly or annual reports are filed. Analyst ratings, price targets, and AI-generated insights are updated daily. Breaking news related to CRDL is aggregated continuously from premium financial news sources throughout the day.
What are the growth catalysts for CRDL?
Growth catalysts for Cardiol Therapeutics Inc. (CRDL) can include several categories: product catalysts (new launches, FDA approvals, patent grants), financial catalysts (earnings beats, margin expansion, share buybacks), strategic catalysts (acquisitions, partnerships, market expansion into new regions), and macro catalysts (favorable regulation, industry tailwinds, secular growth trends). Our AI analyzes Cardiol Therapeutics Inc.'s specific catalysts using earnings transcripts, SEC filings, and news sentiment to identify the most impactful near-term and long-term drivers.
Who are CRDL's main competitors?
Cardiol Therapeutics Inc. (CRDL) competes with companies in its industry that target similar customers, markets, or product categories. Competitor analysis involves comparing key metrics: market share, revenue growth rates, profit margins, R&D spending, and valuation multiples. Understanding competitive positioning helps investors assess whether CRDL has a sustainable competitive advantage (moat) through brand strength, network effects, cost leadership, or switching costs. Our Competitors section provides a side-by-side comparison with relevant peers.
What do analysts say about CRDL?
Wall Street analyst coverage for CRDL includes consensus ratings (buy, hold, or sell), 12-month price targets, and earnings estimates. Analyst opinions are aggregated from major investment banks and research firms. Key metrics to watch include the consensus price target (average, high, and low estimates), the number of analysts covering the stock, any recent rating changes (upgrades or downgrades), and how actual earnings compare to analyst estimates (beat or miss history). Our platform aggregates these from multiple data providers for a comprehensive view.
What is CRDL's market cap?
Market capitalization (market cap) for CRDL is calculated by multiplying the current share price by the total number of outstanding shares. It represents the market's total valuation of the company. Stocks are typically categorized as mega-cap ($200B+), large-cap ($10B-$200B), mid-cap ($2B-$10B), small-cap ($300M-$2B), or micro-cap (under $300M). Market cap influences index inclusion, institutional ownership eligibility, and risk profile. Our Key Statistics section shows CRDL's current market cap alongside enterprise value and other valuation metrics.
How has CRDL stock performed recently?
CRDL's recent stock performance can be evaluated across multiple timeframes: daily price changes, week-over-week momentum, monthly trends, and year-to-date returns. Important performance indicators include the stock's 52-week high and low, moving averages (50-day and 200-day SMA), relative strength index (RSI), and volume trends. Comparing CRDL's performance against its sector index and the S&P 500 provides context on whether it is outperforming or underperforming the broader market.
What are the risks of investing in CRDL?
Key risk categories for CRDL include: market risk (overall market downturns affecting stock prices), company-specific risk (management changes, product failures, competitive threats), financial risk (high debt levels, cash burn, dilution from stock issuance), regulatory risk (government policy changes, lawsuits, compliance issues), and macroeconomic risk (interest rate changes, inflation, currency fluctuations). Beta measures CRDL's volatility relative to the market - a beta above 1.0 means higher volatility than the S&P 500. Our AI-generated risk assessment identifies the most relevant risk factors for this specific stock.
Are insiders buying or selling CRDL?
Insider trading activity for CRDL tracks purchases and sales by company executives, directors, and major shareholders (10%+ owners) as reported in SEC Form 4 filings. Insider buying is generally considered a bullish signal because insiders have the deepest knowledge of company operations, while selling may have various motivations (diversification, tax planning, pre-planned 10b5-1 trading plans). Key metrics include the buy-to-sell ratio, total dollar value of insider transactions, and whether multiple insiders are trading in the same direction. Our Insider Flow tab shows recent transactions with dates and dollar amounts.
Is CRDL a good stock for beginners?
Cardiol Therapeutics Inc. (CRDL) can be suitable for beginner investors depending on several factors. Look at the MoonshotScore on this page for an overall AI-powered assessment of growth potential and risk. Beginners should also check the company's market cap (larger companies tend to be less volatile), gross margin (higher margins mean stronger business fundamentals), and cash position (healthy cash reduces bankruptcy risk). Always start with a small position size and never invest money you cannot afford to lose.
How risky is CRDL for first-time investors?
Every stock carries risk, including Cardiol Therapeutics Inc. (CRDL). First-time investors should review the Risk Factors section on this page for company-specific risks. Key risk indicators include price volatility (check the chart for daily swings), insider selling activity (see Insider Flow tab), and cash runway (see MoonshotScore breakdown). A diversified portfolio with an index fund like the S&P 500 as a core holding is generally recommended before adding individual stocks like CRDL.
Disclaimer: This content is for informational purposes only and does not constitute investment advice. Always do your own research and consult a financial advisor.
Data provided for informational purposes only.
- Information is based on available data and may be subject to change.
- Investment in clinical-stage companies carries significant risk.