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Innate Pharma S.A. (IPHYF)

$1.65 +$0.00 (+0.00%) |CouncilHOLD · 44 · C
Bottom line: HOLD — our Council read (44/100) and AI Score (44/100) broadly agree.
MCap: $154.94M| Vol: 200| 52-wk range: $1.31 – $2.25
Data from FMP · Methodology

For informational purposes only. Not financial advice. Analysis by Sedat ANAK, Founder & Editor-in-Chief | AI-powered analysis. Data sourced from SEC filings and institutional-grade financial providers. Editorially reviewed. Not financial advice.

Innate Pharma S.A. (IPHYF) trades at $1.65 with AI Score 44/100 (Grade C). Innate Pharma S. A. is a French biotechnology company focused on developing innovative antibody-based immunotherapies, primarily for cancer and inflammatory conditions. Market cap: $154.94M, Sector: Healthcare.

Price live · AI analysis from Jun 14, 2026
Innate Pharma S.A. is a French biotechnology company focused on developing innovative antibody-based immunotherapies, primarily for cancer and inflammatory conditions. The company leverages a robust clinical pipeline, including Phase III and Phase II candidates, supported by strategic partnerships with major pharmaceutical firms.

Analyst Coverage for IPHYF: IPHYF does not currently have published analyst price targets in our coverage universe. This is common for smaller-cap names with limited Wall Street coverage. In the absence of analyst consensus, our AI model evaluates IPHYF against Healthcare peers across nine fundamental dimensions and assigns an underweight signal based on the underlying data.

Council Score · Weighted Average of 3 Disciplines
HOLD 44/100 · C

IPHYF: the 1 perspectives are evenly split.

How is this calculated? →
Council Score · 8 perspectives · See tabs for details →

Innate Pharma S.A. (IPHYF) Healthcare & Pipeline Overview

CEOJonathan E. Dickinson
Employees174
HeadquartersMarseille, France
IPO Year2015

Innate Pharma S.A. is a French biotechnology firm specializing in the discovery and development of antibody-based immunotherapies for oncology and inflammatory diseases. With a pipeline featuring Phase III and Phase II candidates like Monalizumab and Lacutamab, the company strategically partners with global pharmaceutical leaders to advance its innovative therapeutic programs.

Data Provenance | Financial Data Quantitative Analysis NASDAQ Analysis: Jun 14, 2026

What Is the Investment Thesis for IPHYF?

Innate Pharma S.A. presents an investment profile centered on its advanced and diversified clinical pipeline, particularly its Phase III candidate Monalizumab for various solid tumors, and Phase II assets like Lacutamab and Avdoralimab. The company's strategic partnerships with major pharmaceutical entities such as AstraZeneca and Sanofi provide critical validation, funding, and potential pathways for commercialization, mitigating some of the inherent capital intensity of drug development. The focus on antibody-based immunotherapies targeting both oncology and inflammatory conditions positions Innate Pharma in high-growth therapeutic areas. Key value drivers include successful clinical trial outcomes, especially for Monalizumab, which could trigger significant milestone payments and future royalties. However, the company's substantial negative profit margin of -1764.5% underscores its reliance on continued R&D investment and external funding, typical for a clinical-stage biotechnology firm. The OTC listing also introduces risks related to liquidity and disclosure. Future growth is contingent on the successful progression of its pipeline through regulatory approvals and effective commercialization strategies, either independently or through its robust partnership network.

Based on FMP financials and quantitative analysis

IPHYF Key Highlights

  • Market Capitalization: $0.15 billion, positioning Innate Pharma S.A. as a small-cap biotechnology company focused on specialized therapeutic areas.
  • Profit Margin: -1764.5%, reflecting significant ongoing research and development expenditures typical for a clinical-stage pharmaceutical firm prior to commercial product revenue.
  • Gross Margin: 100.0%, indicating that current revenue streams are likely derived from licensing agreements or collaboration milestones rather than direct product sales, which typically incur cost of goods sold.
  • Beta: 0.89, suggesting that the stock's volatility is slightly lower than the overall market, which can be unusual for a biotechnology company heavily reliant on clinical trial outcomes.
  • Employee Count: 181 employees, supporting a focused and specialized team dedicated to the discovery, development, and clinical management of its antibody-based therapeutic pipeline.

Who Are IPHYF's Competitors?

IPHYF is benchmarked below against 8 industry peers on price, market cap, and our AI MoonshotScore.

Company Price Change Market Cap AI Score
SNDX Syndax Pharmaceuticals, Inc. $21.82 +4.45% $1.93B 79
ANAB AnaptysBio, Inc. $63.42 -3.07% $2.73B 79
CGEN Compugen Ltd. $2.28 +7.04% $215.58M 76
ABCL AbCellera Biologics Inc. $8.11 +6.71% $2.48B 76
RNAM Avidity Biosciences Inc $72.86 +0.05% $11.26B 68
NWPHF Newron Pharmaceuticals S.p.A. $20.00 +0.00% $416.12M 68
SLGL Sol-Gel Technologies Ltd. $74.01 +2.81% $207.96M 68
MIRM Mirum Pharmaceuticals, Inc. $125.59 +4.26% $6.30B 68

AI Score by Stock Expert AI · Price data: FMP / Yahoo Finance

What Are IPHYF's Key Strengths?

  • Advanced clinical pipeline with a Phase III candidate (Monalizumab) and multiple Phase II assets (Lacutamab, Avdoralimab).
  • Strategic partnerships with major pharmaceutical companies (AstraZeneca, Sanofi, Novo Nordisk) providing funding, expertise, and potential commercialization channels.
  • Specialized focus on antibody-based immunotherapies targeting the innate immune system, addressing high-need oncology and inflammatory conditions.
  • Diversified pipeline addressing multiple indications, reducing reliance on a single drug or therapeutic area.
  • Established company with a founding year of 1999 and a dedicated team of 181 employees.

What Are IPHYF's Weaknesses?

  • Significant negative profit margin (-1764.5%) indicating substantial cash burn and reliance on external funding for R&D.
  • Operating in the highly capital-intensive and risky biotechnology sector, where clinical trial failures are common.
  • OTC market listing, which typically entails lower liquidity, less stringent reporting requirements, and reduced investor visibility.
  • No direct product revenue, with current gross margin of 100% implying revenue primarily from collaborations rather than commercial sales.
  • Dependence on partners for the progression and potential commercialization of key pipeline assets.

What Could Drive IPHYF Stock Higher?

  • Anticipated data readouts from the Phase III clinical trials for Monalizumab in advanced solid tumors, which could significantly impact the drug's regulatory pathway and commercial potential.
  • Release of Phase II clinical trial results for Lacutamab (IPH4102) in cutaneous T-cell and peripheral T-cell lymphoma, and refractory Sézary syndrome, potentially validating its efficacy in these high-need indications.
  • Presentation of Phase II clinical data for Avdoralimab (IPH5401) across various inflammatory conditions, including bullous pemphigoid and chronic spontaneous urticaria, diversifying the company's therapeutic reach.
  • Achievement of development and commercialization milestones under existing strategic alliances with partners like AstraZeneca and Sanofi, triggering potential payments and demonstrating continued progress.
  • Advancement of early-stage preclinical candidates, such as IPH5201, IPH5301, and IPH6101, into Phase I clinical trials, expanding the future pipeline and addressing new therapeutic targets.

What Are the Key Risks for IPHYF?

  • Financial-distress signal — its Altman Z-Score of -13.41 sits in the distress zone (elevated bankruptcy risk).
  • Weak fundamentals — a Piotroski F-Score of 3/9 flags soft profitability, leverage or efficiency.
  • Significant negative profit margin of -1764.5%, indicating substantial cash burn and a continuous need for external funding to sustain its extensive research and development activities.
  • Clinical trial failures or unexpected safety concerns for any of its pipeline candidates, particularly Monalizumab in Phase III, which could lead to substantial value erosion and delays in commercialization.
  • Intense competition within the highly dynamic biotechnology sector, especially in oncology and immunology, from numerous established pharmaceutical companies and emerging biotech firms.
  • Regulatory hurdles, delays in obtaining marketing approvals, or unfavorable decisions from health authorities for its drug candidates, impacting time-to-market and revenue generation.
  • Risks associated with its OTC market listing, including lower trading liquidity, less stringent disclosure requirements, and potential for increased price volatility compared to exchange-listed stocks.

What Are the Growth Opportunities for IPHYF?

  • Growth opportunity 1: The advancement and potential commercialization of Monalizumab represent a significant growth driver. Currently in Phase III clinical trials for advanced solid tumors, including colorectal, lung, and head and neck cancers, successful trial outcomes could lead to regulatory approval. The market for advanced solid tumor treatments is substantial, with global oncology drug sales projected to reach hundreds of billions of dollars annually. Monalizumab's progression could unlock significant milestone payments from partners and future royalty streams, providing a critical revenue inflection point for Innate Pharma within the next few years, contingent on positive data and regulatory success.
  • Growth opportunity 2: The successful development of Lacutamab (IPH4102) offers another key avenue for growth. This anti-KIR3DL2 antibody is in Phase II clinical evaluation for cutaneous T-cell and peripheral T-cell lymphoma, as well as refractory Sézary syndrome. These are rare but aggressive forms of lymphoma with high unmet medical needs. Positive results from these trials could position Lacutamab as a novel treatment option in these niche oncology markets. The orphan drug designation potential for such indications often leads to expedited review processes and extended market exclusivity, providing a strategic advantage and potential for significant revenue generation in specialized therapeutic areas.
  • Growth opportunity 3: Expansion into inflammatory conditions with Avdoralimab (IPH5401) diversifies Innate Pharma's pipeline beyond oncology. This monoclonal antibody, designed to block C5a binding to C5aR1, is in Phase II clinical assessment for conditions such as COVID-19, bullous pemphigoid, and chronic spontaneous urticaria. The global market for immunology and inflammatory disease treatments is vast and continuously expanding. Successful development in these areas could open new, large therapeutic markets, reducing the company's sole reliance on oncology assets and providing multiple shots on goal for future revenue streams, with potential readouts expected within the next 2-4 years.
  • Growth opportunity 4: The progression of Innate Pharma's early-stage oncology pipeline, including IPH5201, IPH5301, and IPH6101, represents long-term growth potential. IPH5201 targets the CD39 immunosuppressive pathway, IPH5301 targets the CD73 adenosine pathway, and IPH6101 is an NKp46-based NK cell engager. These candidates aim to enhance anti-tumor immunity by modulating key immunosuppressive mechanisms. Successful advancement of these preclinical and Phase I programs into later-stage clinical trials, potentially through new or existing partnerships, could significantly bolster Innate Pharma's future pipeline value and market position in the rapidly evolving field of immuno-oncology, with timelines extending beyond five years.
  • Growth opportunity 5: Leveraging strategic pharmaceutical partnerships is crucial for Innate Pharma's sustained growth. Collaborations with major companies like AstraZeneca, Novo Nordisk A/S, Sanofi, and MedImmune Limited provide access to substantial funding, advanced research capabilities, and global commercialization networks. These alliances validate Innate Pharma's scientific approach and pipeline assets, while also providing milestone payments and potential royalties upon successful drug development and market entry. Such partnerships reduce the financial burden of extensive clinical trials and market access, allowing Innate Pharma to focus on its core strength of innovative drug discovery and early-stage development, thereby accelerating the path to market for its therapies.

What Opportunities Does IPHYF Have?

  • Successful completion of Monalizumab's Phase III trials and subsequent regulatory approval, leading to significant milestone payments and royalties.
  • Expansion of Lacutamab's and Avdoralimab's therapeutic indications or market reach based on positive Phase II data.
  • Advancement of early-stage preclinical and Phase I candidates into later clinical phases, creating future pipeline value.
  • Formation of new strategic alliances or expansion of existing partnerships to accelerate development and commercialization efforts.
  • Potential for orphan drug designations for specific indications, offering market exclusivity and expedited regulatory pathways.

What Threats Does IPHYF Face?

  • Clinical trial failures or unexpected adverse events for any of its pipeline candidates, particularly those in advanced stages.
  • Intense competition from other biotechnology and pharmaceutical companies developing similar or superior immunotherapies.
  • Regulatory hurdles, delays, or non-approvals from health authorities for its drug candidates.
  • Funding challenges or inability to secure sufficient capital to sustain extensive R&D and clinical trial operations.
  • Patent expirations or challenges to intellectual property rights, potentially leading to generic or biosimilar competition in the future.

What Are IPHYF's Competitive Advantages?

  • Proprietary Antibody Platform: Specialized expertise in developing antibody-based immunotherapies targeting the innate immune system.
  • Diversified Clinical Pipeline: Multiple candidates in various stages of development (Phase III, Phase II, Phase I, preclinical) across oncology and inflammatory diseases.
  • Strategic Pharmaceutical Partnerships: Alliances with global pharma leaders like AstraZeneca and Sanofi provide validation, funding, and access to broader development and commercialization resources.
  • Specific Target Focus: Unique focus on targets like KIR3DL2, C5aR1, CD39, CD73, and NKp46, which are critical in immune modulation for therapeutic effect.
  • Intellectual Property: Patents protecting its novel antibody candidates and therapeutic approaches, providing market exclusivity upon approval.

What Does IPHYF Do?

Innate Pharma S.A., established in 1999 and headquartered in Marseille, France, operates as a global biotechnology company dedicated to the discovery, advancement, and eventual commercialization of pioneering antibody-based therapies. The company's core focus lies in addressing various oncological conditions, though its pipeline also extends to inflammatory diseases. Innate Pharma's clinical development portfolio is robust, featuring several promising candidates. Lacutamab (IPH4102), an anti-KIR3DL2 antibody, is currently undergoing Phase II clinical evaluation for its potential in treating cutaneous T-cell and peripheral T-cell lymphoma, alongside refractory Sézary syndrome. Monalizumab, an immune checkpoint inhibitor, represents a significant asset, having progressed to Phase III clinical trials for advanced solid tumors, specifically targeting colorectal, lung, and head and neck cancers. Another key candidate, Avdoralimab (IPH5401), is a monoclonal antibody designed to block C5a binding to C5aR1, and is in Phase II clinical assessment for a range of inflammatory conditions, including COVID-19, bullous pemphigoid, and chronic spontaneous urticaria. Further enriching its early-stage pipeline are IPH5201, a blocking antibody in Phase I trials targeting the CD39 immunosuppressive pathway, and IPH5301, an anti-CD73 antibody aimed at enhancing anti-tumor immunity by modulating the immunosuppressive adenosine pathway. Additionally, IPH6101 is an NKp46-based NK cell engager program focused on developing up to two bispecific NK cell engagers. Beyond these clinical programs, Innate Pharma maintains active preclinical research, exploring candidates such as IPH43 (an anti-MICA/B antibody-drug conjugate), an Anti-Siglec-9 antibody program, IPH65 (a proprietary tetraspecific antibody), IPH25 (a checkpoint inhibitor), and the IPH62 and IPH64 programs. To bolster its development efforts and expand its market reach, Innate Pharma has forged strategic alliances and licensing agreements with prominent pharmaceutical companies, including AstraZeneca, Novo Nordisk A/S, Sanofi, and Orega Biotech, alongside a co-development and license agreement with MedImmune Limited. These collaborations are integral to the company's strategy for advancing its innovative therapies.

What Products and Services Does IPHYF Offer?

  • Discovers and develops antibody-based immunotherapies for cancer and inflammatory conditions.
  • Advances Lacutamab (IPH4102), an anti-KIR3DL2 antibody, through Phase II for cutaneous T-cell and peripheral T-cell lymphoma.
  • Progresses Monalizumab, an immune checkpoint inhibitor, through Phase III for advanced solid tumors like colorectal, lung, and head and neck cancers.
  • Develops Avdoralimab (IPH5401), a monoclonal antibody, in Phase II for inflammatory conditions including COVID-19, bullous pemphigoid, and chronic spontaneous urticaria.
  • Conducts preclinical and Phase I research on novel oncology targets such as CD39 (IPH5201), CD73 (IPH5301), and NKp46 (IPH6101).
  • Engages in strategic alliances and licensing agreements with major pharmaceutical companies like AstraZeneca, Sanofi, and Novo Nordisk.
  • Focuses on harnessing the innate immune system to create innovative therapeutic solutions.
  • Maintains an active preclinical pipeline with candidates like IPH43, Anti-Siglec-9, IPH65, IPH25, IPH62, and IPH64.

How Does IPHYF Make Money?

  • Drug Discovery & Development: Invests in proprietary research to identify novel antibody targets and develop therapeutic candidates.
  • Licensing & Collaboration Agreements: Generates revenue through upfront payments, milestone achievements, and potential royalties from partnerships with larger pharmaceutical companies.
  • Co-development: Shares development costs and potential future profits with partners under specific agreements, such as with MedImmune Limited.
  • Clinical Pipeline Progression: Focuses on advancing candidates through various clinical trial phases to increase their value and market potential.
  • Potential Future Commercialization: Aims for market approval and commercialization of its therapies, either independently or through its partners.

What Industry Does IPHYF Operate In?

Innate Pharma S.A. operates within the highly dynamic and competitive biotechnology industry, specifically focusing on the development of antibody-based immunotherapies. This sector is characterized by intense research and development, significant capital requirements, and a high-risk, high-reward profile tied to clinical trial success and regulatory approvals. The global oncology and immunology markets, which Innate Pharma targets, represent substantial and growing segments within healthcare, driven by increasing disease prevalence and advancements in therapeutic understanding. The company positions itself as a specialist in harnessing the innate immune system to combat cancer and inflammatory conditions, differentiating itself through its proprietary antibody platform and specific targets. The competitive landscape includes numerous established pharmaceutical giants and emerging biotech firms, all vying for market share with innovative therapies. Innate Pharma's strategy of forming strategic alliances with larger pharmaceutical companies is a common approach in this industry, allowing it to leverage external resources for drug development and potential commercialization while mitigating some financial risks.

Who Are IPHYF's Key Customers?

  • Patients suffering from various oncological conditions, including lymphomas and solid tumors.
  • Patients with inflammatory conditions such as bullous pemphigoid, chronic spontaneous urticaria, and COVID-19.
  • Major pharmaceutical companies seeking innovative drug candidates and development expertise for their pipelines.
  • Healthcare providers and oncologists who will prescribe and administer approved therapies.
AI Confidence: 70% Updated: Jun 14, 2026

Company Profile

Innate Pharma S.A. operates in the Biotechnology industry within the Healthcare sector. It is headquartered in Marseille, FR. The company is led by CEO Jonathan E. Dickinson. IPHYF has traded publicly since 2015.

How Innate Pharma S.A. Is Valued

Innate Pharma S.A. carries a market capitalization of $154.94M, placing it in the micro-cap category. Relative to its peer group, IPHYF's quantitative score of 44/100 is below the peer average of 76/100.

Key Financial Metrics

Return on assets is -78.4%, showing how much profit it generates from its asset base. Its free cash flow yield is -35.7%, a gauge of the cash the business throws off relative to its market value. A current ratio of 1.27 indicates the company holds enough short-term assets to cover its near-term obligations. Its earnings yield is -34.1%, the inverse of the P/E and a quick read on earnings relative to price.

F-Score 3/9Financial Health

Innate Pharma S.A.'s Piotroski F-Score is 3/9, a 9-point checklist of profitability, leverage and efficiency — flagging fundamental weakness worth scrutiny. Its Altman Z-Score of -13.41 places it in the distress zone, a signal of elevated financial risk.

FY2026 estForward Outlook

Wall Street analysts project Innate Pharma S.A. revenue of about $30.4M for fiscal 2026, with EPS near $-0.25. The estimate reflects 6 contributing analysts.

IPHYF Financials

Fundamental Snapshot

Revenue Growth (FY)
-77.9%
Net Income Growth (FY)
+0.6%
EPS Growth (FY)
+9.8%
Current Ratio
1.3

Based on FMP financials and quantitative analysis · FY 2025

Bull Case vs Bear Case

Bull Case

  • Advanced clinical pipeline with a Phase III candidate (Monalizumab) and multiple Phase II assets (Lacutamab, Avdoralimab).
  • Strategic partnerships with major pharmaceutical companies (AstraZeneca, Sanofi, Novo Nordisk) providing funding, expertise, and potential commercialization channels.
  • Specialized focus on antibody-based immunotherapies targeting the innate immune system, addressing high-need oncology and inflammatory conditions.
  • Diversified pipeline addressing multiple indications, reducing reliance on a single drug or therapeutic area.

Bear Case

  • Significant negative profit margin (-1764.5%) indicating substantial cash burn and reliance on external funding for R&D.
  • Operating in the highly capital-intensive and risky biotechnology sector, where clinical trial failures are common.
  • OTC market listing, which typically entails lower liquidity, less stringent reporting requirements, and reduced investor visibility.
  • No direct product revenue, with current gross margin of 100% implying revenue primarily from collaborations rather than commercial sales.

AI-generated arguments based on insider flow, news sentiment and technicals — not financial advice · July 2026

IPHYF Latest News

IPHYF Analyst Consensus

Consensus Rating

Aggregated Buy/Hold/Sell recommendations from Benzinga, Yahoo Finance, and Finnhub for IPHYF.

Price Targets

Wall Street price target analysis for IPHYF.

IPHYF MoonshotScore

44/100

What does this score mean?

The MoonshotScore rates IPHYF's growth potential on a scale of 0-100 across multiple factors including innovation, market disruption, financial health, and momentum.

Leadership: Jonathan E. Dickinson

Chief Executive Officer

Jonathan E. Dickinson serves as the Chief Executive Officer of Innate Pharma S.A., overseeing the strategic direction and operational execution of the biotechnology firm. While specific details regarding his prior career history, educational background, or previous roles are not provided, his leadership encompasses the management of the company's 181 employees. His role involves guiding Innate Pharma's focus on the discovery, development, and commercialization of innovative antibody-based therapies within the competitive healthcare sector.

Track Record: Under Jonathan E. Dickinson's leadership, Innate Pharma S.A. has continued to advance its robust clinical pipeline, including the progression of Monalizumab into Phase III trials for advanced solid tumors. The company has also maintained and expanded its strategic alliances with major pharmaceutical partners such as AstraZeneca, Novo Nordisk A/S, and Sanofi, which are crucial for funding and expertise. His tenure is marked by ongoing efforts to develop novel immunotherapies and manage a diversified portfolio of preclinical and clinical-stage assets.

IPHYF OTC Market Information

Innate Pharma S.A. trades on the OTC (Over-The-Counter) market under the 'OTC Other' tier. This classification represents the lowest tier of the OTC market, typically for companies that do not meet the listing requirements of higher tiers like OTCQX or OTCQB, or major exchanges like NYSE or NASDAQ. Companies in the 'OTC Other' tier may have limited public disclosure, less stringent financial reporting requirements, and can include a wide range of entities from legitimate businesses to shell companies. This tier often lacks the regulatory oversight and transparency associated with exchange-listed securities, making due diligence particularly critical for investors.

  • OTC Tier: OTC Other
  • Disclosure Status: Unknown
Liquidity: As an OTC-listed stock, particularly in the 'OTC Other' tier, IPHYF likely experiences significantly lower trading liquidity compared to exchange-listed securities. This can manifest as lower daily trading volumes, wider bid-ask spreads, and potential difficulty for investors to execute trades quickly or at desired prices. The limited number of market makers and reduced investor interest typically contribute to this illiquidity, making the stock potentially harder to buy or sell without impacting its price. Investors should anticipate challenges in entering or exiting positions efficiently.
OTC Risk Factors:
  • Limited Public Information: Less stringent reporting requirements on OTC markets can lead to a lack of comprehensive and timely financial or operational data.
  • Lower Liquidity: Reduced trading volume and wider bid-ask spreads can make it difficult to buy or sell shares at a fair price, increasing transaction costs.
  • Price Volatility: OTC stocks can be highly volatile due to lower trading volumes, limited information, and susceptibility to speculative trading.
  • Potential for Manipulation: Less regulatory oversight compared to major exchanges can increase the risk of market manipulation.
  • Lack of Analyst Coverage: OTC stocks often receive little to no coverage from institutional analysts, leading to less independent research and valuation insights.
Due Diligence Checklist:
  • Verify the availability and recency of financial statements and corporate filings, even if less frequent than exchange-listed companies.
  • Thoroughly research the company's clinical trial progress, regulatory updates, and scientific publications for its pipeline assets.
  • Investigate the legitimacy and terms of all strategic partnerships and licensing agreements, as these are critical for funding and validation.
  • Assess the management team's experience and track record, looking for evidence of successful drug development or commercialization.
  • Understand the specific regulatory landscape for its therapeutic areas and the potential for market approval.
  • Evaluate the company's cash burn rate and funding runway, given its negative profit margin and R&D intensity.
  • Scrutinize the company's intellectual property portfolio and patent protections.
Legitimacy Signals:
  • Established Founding Date: Founded in 1999, indicating a long operational history for a biotechnology firm.
  • Significant Employee Base: Employs 181 individuals, suggesting a substantive operational presence and research capabilities.
  • Strategic Pharmaceutical Partnerships: Has established alliances with major, reputable pharmaceutical companies like AstraZeneca, Novo Nordisk A/S, Sanofi, and MedImmune Limited, which provides external validation.
  • Advanced Clinical Pipeline: Possesses candidates in Phase III and Phase II clinical trials, signifying substantial investment and progress in drug development.
  • Headquartered in France: Operating from Marseille, France, provides a clear and verifiable physical presence.

Common Questions About IPHYF (Healthcare)

What does Innate Pharma S.A. do?

Innate Pharma S.A. is a biotechnology company based in Marseille, France, focused on the discovery, development, and commercialization of innovative antibody-based immunotherapies. The company's primary therapeutic focus is oncology, with a robust clinical pipeline including candidates like Monalizumab, an immune checkpoint inhibitor in Phase III for advanced solid tumors, and Lacutamab (IPH4102), an anti-KIR3DL2 antibody in Phase II for lymphomas. Beyond cancer, Innate Pharma is also developing Avdoralimab (IPH5401) for inflammatory conditions. Its business model relies on advancing these proprietary drug candidates through clinical trials and leveraging strategic alliances with major pharmaceutical companies such as AstraZeneca and Sanofi for co-development and potential commercialization, thereby generating revenue through milestone payments and royalties.

What are the key growth opportunities for IPHYF in healthcare?

Key growth opportunities for Innate Pharma S.A. in the healthcare sector are primarily driven by the progression and potential commercialization of its diverse clinical pipeline. The most immediate opportunity lies with Monalizumab, currently in Phase III trials for advanced solid tumors; successful approval could unlock significant market potential and revenue streams through its partnership. Further growth is anticipated from Lacutamab (IPH4102) in Phase II for lymphomas and Avdoralimab (IPH5401) in Phase II for inflammatory conditions, which could expand the company's presence into high-need therapeutic areas. Additionally, the advancement of its preclinical and early-stage clinical programs, such as IPH5201 and IPH5301, provides long-term growth prospects by targeting novel immunosuppressive pathways in oncology. Strategic alliances with major pharmaceutical companies also represent a crucial growth mechanism, providing capital, expertise, and broader market access for its innovative therapies.

How does Innate Pharma S.A. manage clinical trial risks?

Innate Pharma S.A. manages clinical trial risks through a multi-faceted approach inherent to its operational strategy. Firstly, the company maintains a diversified pipeline, with multiple drug candidates targeting different indications and immune pathways, reducing reliance on the success of any single asset. For instance, Monalizumab is in Phase III, while Lacutamab and Avdoralimab are in Phase II, and several others are in earlier stages. Secondly, Innate Pharma leverages strategic partnerships with major pharmaceutical companies like AstraZeneca and Sanofi. These collaborations provide not only financial resources but also access to extensive clinical development expertise, regulatory knowledge, and global infrastructure, which can help optimize trial design and execution, thereby mitigating some of the inherent risks. Furthermore, the company's specialized focus on antibody-based immunotherapies and innate immune system modulation reflects a deep scientific understanding, which can contribute to more targeted and potentially effective drug candidates, although clinical success is never guaranteed.

What are the main risks for IPHYF?

The main risks for Innate Pharma S.A. are multifaceted, stemming from both its operational model as a clinical-stage biotechnology company and its market listing. Operationally, the most significant risks include potential clinical trial failures or unexpected adverse events for any of its pipeline candidates, particularly Monalizumab in Phase III, which could severely impact its valuation and future prospects. The company's substantial negative profit margin of -1764.5% highlights its ongoing reliance on external funding and partnerships to sustain its extensive R&D, posing a financial risk if capital becomes scarce. Furthermore, the biotechnology sector is highly competitive, with numerous players vying for market share, creating a risk of superior therapies emerging. From a market perspective, its OTC listing carries inherent risks such as lower liquidity, less stringent disclosure requirements, and increased price volatility, which can make the stock less attractive to institutional investors and harder to trade efficiently.

What are the key factors to evaluate for IPHYF?

Innate Pharma S.A. (IPHYF) holds an AI score of 44/100 (low). Not financial advice.

How frequently does IPHYF data refresh on this page?

IPHYF prices update in real time during U.S. market hours. Fundamentals refresh after quarterly filings; analyst ratings and AI insights update daily; news is aggregated continuously.

What has driven IPHYF's recent stock price performance?

Innate Pharma S.A. (IPHYF) moves on earnings results, analyst revisions, sector rotation, and market sentiment. Notable catalyst: Advanced clinical pipeline with a Phase III candidate (Monalizumab) and multiple Phase II assets (Lacutamab, Avdoralimab). See the News tab for the latest drivers. Past performance does not predict future results.

Should investors consider IPHYF overvalued or undervalued right now?

Valuing Innate Pharma S.A. (IPHYF) requires multiple metrics. Compare P/E, P/S, and EV/EBITDA against sector peers for a full view.

Disclaimer: This content is for informational purposes only and does not constitute investment advice. Always do your own research and consult a financial advisor.

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