Merck & Co., Inc.
MRK - NYSE - $112.17 ▲ +%2.73
-
Earnings Thu 29 Oct

Merck opens the
books on Thursday evening.

7 analysts' median target is $133[FMP target], stock is $112, +18.6% upside potential. After Q1 +0% EPS beat[FMP earnings], the stock moved +2.7%.

summary below
Quick Take - in 40 seconds
C
BUY Council 1/6 - Moonshot 49

C = MoonshotScore 49[9-pillar formula] + Council 1/6[6-lens rule]. Form 4: 0 transactions[FMP Form 4].

Q1 consensus: revenue $17.4B[FMP est], EPS $2.33[FMP est]. 5 consecutive quarters of beat[FMP earnings].

$2.33 EPS Estimate Last year $-1.28 - +9% YoY YoY
5 Beat Streak Expectations beaten consecutively for the last 5 quarters

Q1 EPS +0% beat[FMP] but the stock +2.7% D+1[FMP D+1]. Caroline Litchfield promised $1.0B CapEx + a sequential decline in Q1 during the Q1 earnings call[Caroline Litchfield capex transcript].

Watchlist

6 metrics stand out this quarter.

8% Investor Focus

Keytruda Growth

keytruda_growth

Sales of the KEYTRUDA family of products increased 8% to $8 billion, with global growth driven by continued strong demand from metastatic indications and robust uptake in earlier-stage cancers.

"In Oncology, sales of the KEYTRUDA family of products which includes KEYTRUDA and KEYTRUDA QLEX, increased 8% to $8 billion, with global growth driven by continued strong demand from metastatic indications and robust uptake in earlier-stage cancers."

- Caroline Litchfield, CFO - Q1 FY26 Earnings Call - April 30, 2026
43% Investor Focus

Welireg Growth

welireg_growth

WELIREG sales increased 43% to $199 million driven by continued uptake from ongoing launches in international markets and increased use in certain patients with previously treated advanced renal cell carcinoma in the U.S.

"Notably, WELIREG sales increased 43% to $199 million driven by continued uptake from ongoing launches in international markets and increased use in certain patients with previously treated advanced renal cell carcinoma in the U.S."

- Caroline Litchfield, CFO - Q1 FY26 Earnings Call - April 30, 2026
$142 million Investor Focus

Capvaxive Growth

capvaxive_growth

In pneumococcal, CAPVAXIVE continues to progress well, with sales of $142 million, an increase of 31%.

"In pneumococcal, CAPVAXIVE continues to progress well, with sales of $142 million, an increase of 31%."

- Caroline Litchfield, CFO - Q1 FY26 Earnings Call - April 30, 2026
$70 billion Investor Focus

20 New Products Potential

20_new_products_potential

We're confident that this change will best position us to deliver on a potential commercial opportunity of over $70 billion by the mid-2030s from these 20-plus anticipated new growth drivers alone.

"We're confident that this change will best position us to deliver on a potential commercial opportunity of over $70 billion by the mid-2030s from these 20-plus anticipated new growth drivers alone."

- Robert Davis, Chairman and Chief Executive Officer - Q1 FY26 Earnings Call - April 30, 2026
$525 million Investor Focus

Winrevair Sales

winrevair_sales

Global sales of WINREVAIR were $525 million, a reflection of the continued strong demand for this important therapy.

"Global sales were $525 million, a reflection of the continued strong demand for this important therapy."

- Caroline Litchfield, CFO - Q1 FY26 Earnings Call - April 30, 2026
$1.1 billion Investor Focus

Gardasil Sales Decline

gardasil_sales_decline

GARDASIL sales were $1.1 billion, a decrease of 22%, driven by lower demand in China and Japan, consistent with our expectations.

"In Vaccines and Infectious Diseases, GARDASIL sales were $1.1 billion, a decrease of 22%, driven by lower demand in China and Japan, consistent with our expectations."

- Caroline Litchfield, CFO - Q1 FY26 Earnings Call - April 30, 2026

Stock Expert AI - Methodology

Do our 9 pillars, 7 perspectives, and Munger lens point in the same direction?

Council Score 1 / 6 Bullish

6 investor frameworks. 1 bullish (Ray Dalio), 1 bearish (Ken Griffin), 4 neutral (Jim Simons, Klarman, Buffett, Munger).

How is it calculated? ->
Ray Dalio macro - target upside +18.6%
Ken Griffin flow - 50d MA below
Jim Simons quant - RSI 43
Klarman value - target upside +18.6%
Buffett quality - ROE score 1/5
Munger valuation - target upside +18.6%
Munger's Mindset character & balance sheet lens
Fairly Valued

Quality business, trading at fair value.

How is it calculated? ->
Financial HealthWeak
Margin of SafetyModerate
Interest CoverageAdequate
ROIC vs WACCTight
Technical Levels - Pre-earnings positioning

What levels is the stock being tested at?

RSI(14)
43.0 RSI 43.0 weak momentum, 50d below
MACD
-4.60 price below 50d - resistance dominant
50d MA
$118 stock 4.6% below - short-term resistance
200d MA
$100 stock 12.3% above - long-term support
Volume (10d)
+23% increase - pre-earnings positioning
Resistance
$133
Analyst median target - upgrade trigger if broken
Current
$112
Pre-earnings position
Support
$85
Invalidation - close below this is a technical breakdown
Pattern
Range
$85-$133 band - earnings breakout/breakdown trigger

Past Performance

Merck's last 8 quarters: 5 consecutive beats.

BEAT
Q2 FY25
$2.13 vs $2.03 est - -1.1%
BEAT
Q3 FY25
$2.58 vs $2.36 est - -0.3%
BEAT
Q4 FY25
$2.04 vs $2.01 est - +2.1%
BEAT
Q1 FY26
$-1.28 vs $-1.47 est - +2.7%

Q1 (April 30, 2026): EPS $-1.28 vs $-1.47 est[FMP], +0% beat. D+1 movement: +2.7%[FMP D+1]. Decline despite beat - market reacted to guidance, not numbers.

Three scenarios: what could happen?

EPS < $2.26 (no guidance)

Q1: EPS $-1.28 vs $-1.47 beat[FMP], stock +2.7% D+1[FMP].

Backlog concentration

No RPO/backlog concentration disclosed in Q1 earnings call.

CapEx shock

Q1 CapEx $1.0B[FMP cashflow]. Q1 op margin -11.6%[FMP op margin] - this level in Q1 is sensitive to CapEx revision risk.

Framework - Position discipline

After the data arrives: 3 scenarios, 3 windows

Not advice - a structural framework for earnings night. Decision discipline is yours.

Scenario A - Beat
Q1 EPS > $2.33 + CapEx discipline
Threshold: EPS > $2.33[FMP est].
Target: Break above median target $133[FMP target]; high target $150[FMP] upper bound.
Scenario B - In-Line
EPS approx $2.33 + CapEx < $1.0B
Threshold: EPS approx $2.33[FMP est], Q1 CapEx < $1.0B[FMP].
Target: Consolidation in the band between current $112[FMP] and median $133[FMP].
Scenario C - Miss
EPS < $2.26 or CapEx >= $1.0B
Threshold: EPS < $2.26[FMP estx0.97].
Target: Current $112 below SMA200 $100[FMP], if rejection continues, $85[derived] support activates.
Sizing
Earnings volatility -> max portfolio 1-2%. Waiting for earnings is not a gamble, it's a position entrustment.
Timing
IV crush within 24 hours post-earnings. Waiting for premium decay makes options preferable to spot.
Staging
Don't go all-in at once, divide into 3: initial reaction, 24 hours later, after Friday's close.

Market Outlook

What do 7 analysts say?

Wall Street Consensus
$133
12-month median target price (+18.6% upside potential)
19
BUY
10
HOLD
0
SELL
Risk Management
$85
Invalidation level - critical support threshold
$118 - 50-day MA (below, -4.6%)
$100 - 200-day MA (above, +12.3%)
IV Crush risk (sudden drop in inflated option premiums before earnings): Option premiums are inflated before earnings.
Verdict - MRK Q1 FY27
C

You read it in 5 minutes. When the numbers come out on Thursday evening - you know what you're looking at.

Data arrives at night. The framework is ready now.

Data arrives on Thursday evening. The framework is ready on this page: Q1 EPS threshold $2.33[FMP], CapEx threshold "below $1.0B"[Caroline Litchfield]. Two anchors, three scenarios.

Comparison Stock Expert AI Pro $24/month ($240/year), 77% cheaper than the total of three earnings-tracking tools ($1,059/year -> $240/year).

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Prices as of April 2026. Sources: seekingalpha.com/subscriptions - tipranks.com/pricing - trendspider.com/pricing

Stock Expert AI Pro: $24/month ($240/year). Council 7-lens analysis + MoonshotScore 9-pillar + Insider tracker + Technical levels - all in one platform, for every stock.

Educational tool, not investment advice. Past performance does not guarantee future results.

Calendar

Catalyst Calendar - 90-day forward look

Oct 29, 2026EARNINGSQ1 FY27 results (after market close) + earnings call
Oct 30, 2026PRICEFirst trading day after earnings - 200dMA test + IV crush
Dec 13, 2026FILING10-Q deadline - segment breakdown + RPO detail (SEC rule: quarter-end + 45 days)
~Jan 29, 2027EARNINGSQ2 FY27 (next quarter, date not yet scheduled in FMP)

DATA GAP: Events not in the FMP /stable/calendar feed - Investor day, analyst day, product launches, regulatory dates. These require company IR page scraping or manual calendar entry.

Frequently Asked Questions

What does the MRK earnings preview cover?

This MRK (MRK) earnings preview covers the analyst consensus, key catalysts, and what to watch on the earnings call.

What should investors watch for in MRK earnings?

Consensus EPS, revenue guidance, segment growth rates, and the tone of management commentary — the full breakdown with sources is on this page.