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Axsome Therapeutics, Inc. (AXSM) Stock: Price, Forecast & Analyst Target

Axsome Therapeutics, Inc. (AXSM) — MoonshotScore 33/100 (Weak band), calculated Oct 4, 2026. Price $179.25 (-1.55%), as of the Oct 2, 2026 trading session; market cap $9.39B. Expected results Nov 2, 2026.

Educational signal · not a buy or sell recommendation · How to read this

$179.25 −$2.82 (-1.55%) Market Cap $9.39B

Axsome Therapeutics, Inc. · AXSM · NASDAQ · Healthcare · Biotechnology

Research dated 2026-09-13: Axsome Therapeutics is a commercial biopharmaceutical company selling central nervous system medicines while advancing a broad clinical pipeline across depression, migraine, sleep disorders, pain and neuropsychiatric conditions. The case depends on whether product revenue can outgrow the commercial and research spending that still keeps the business unprofitable and usually cash consumptive.

Price as of Oct 2, 2026

Key Statistics

33 of 100

MoonshotScore v2 · Axsome Therapeutics (AXSM)

Weak
Business Quality Average (56)
Financial Safety Okay (45)
Valuation Full (44)
Growth Durability Growing (69)
Momentum Rising (64)
Why this rating? Method, drivers & history

Bands for the MoonshotScore: Exceptional 80-100 · Strong 65-79 · Fair 45-64 · Weak below 45.

  • Business Quality — Is this a genuinely good business?
  • Financial Safety — Could this blow up on me?
  • Valuation — Am I paying a fair price?
  • Growth Durability — Is the growth real and likely to last?
  • Momentum — Is the market already moving on this?
The ten-second read ·

Durable growth, though the balance sheet is only middling. Business Quality: Average; Financial Safety: Okay; Valuation: Full; Growth Durability: Growing; Momentum: Rising.

  • quarterly revenue $218M (Q2 FY2026, quarter ended Jun 2026)
  • EPS beat 3 of 8
  • Altman Z 6.07 · Piotroski F 3

Helping: durable growth

What has the MoonshotScore done over time?

MoonshotScore snapshots recorded for AXSM (29 recorded, newest six shown)
RecordedScoreBand
33Weak
33Weak
33Weak
33Weak
33Weak
33Weak

The score was 33 in the stored Oct 3, 2026 snapshot and remains 33 in the current publication computed Oct 4, 2026 (0); the largest pillar moves were Financial Safety -1 and Momentum +1; the pillar moves offset under the sector-relative weighting, so the headline score is unchanged. This current publication is not yet represented in the immutable snapshot archive.

Calculation uses the most recent completed US trading session. Live price changes do not update the score immediately.

Computed · Educational signal · not a buy or sell recommendation · How the MoonshotScore is computed →

Price & valuation

Dates shown where recorded
MeasureValueAs of
Latest provided price$179.25
Change on the day-1.55%
52-week range$117.30–$260.19
Market capitalisation$9.39B
Price / earnings (trailing)39.83
Shares traded on the day981.4K
Beta (volatility vs the S&P 500)0.6

Price & events

Weekly closing price with reported quarters marked Weekly closing price from Sep 5, 2025 to Oct 2, 2026: low $116, high $255, latest $179. 4 reported quarters marked, 0 above and 4 below the recorded estimate. $255 $116 high $255 Nov 3, 2025 · Earnings results · reported below the recorded estimate · close $1351Feb 23, 2026 · Earnings results · reported below the recorded estimate · close $1842May 4, 2026 · Earnings results · reported below the recorded estimate · close $2073Aug 10, 2026 · Earnings results · reported below the recorded estimate · close $2134 Sep 5, 2025 Oct 2, 2026 · $179 $125Sep 5, 2025$116Sep 19, 2025$120Oct 3, 2025$128Oct 17, 2025$135Oct 31, 2025$140Nov 14, 2025$152Nov 28, 2025$148Dec 12, 2025$152Dec 26, 2025$169Jan 9, 2026$186Jan 23, 2026$183Feb 6, 2026$184Feb 20, 2026$162Mar 6, 2026$157Mar 20, 2026$169Apr 2, 2026$189Apr 17, 2026$207May 1, 2026$228May 15, 2026$234May 29, 2026$255Jun 12, 2026$242Jun 26, 2026$234Jul 10, 2026$241Jul 24, 2026$213Aug 7, 2026$208Aug 21, 2026$207Sep 4, 2026$208Sep 18, 2026$179Oct 2, 2026

Triangles mark reported quarters on the line: pointing up is above the recorded estimate, down is below, a diamond means no estimate on file. Numbers key to the dated list. Point at or tab to any week for its close.

Events behind the price

  • · Earnings results · below the recorded estimate
  • · Earnings results · below the recorded estimate
  • · Earnings results · below the recorded estimate
  • · Earnings results · below the recorded estimate

Results dates follow the earnings feed; call dates follow the transcript provider. Nearby dates do not establish that an event caused a price move.

Upcoming events

As of

  1. Next results dueProvider estimate

The provider's estimated date can change.

What to watch next

Council Score · weighted blend of 2 available disciplines

Council score for Axsome Therapeutics (AXSM): Split View

47/100 · C

Some lenses disagree with the MoonshotScore. Compare their readings below; each uses a different method.

5-Factor Breakdown

Growth Durability Moderate
Momentum Moderate
Business Quality Neutral
Financial Safety Neutral
Valuation Neutral

Legends Council

2 lenses, 2 current

AI simulations built from the named investors' published principles. Not affiliated with, endorsed by, or the opinion of these individuals. How these lenses are built

Griffin-style lens (simulated) Ken Griffin Favorable read
Englander-style lens (simulated) Izzy Englander Neutral read

Read on: Oct 4, 2026

Munger's Mindset

Balance Sheet & Valuation · historical

Financial Health Weak
Margin of Safety Fairly Valued
Profit Margin Weak
Revenue Growth Strong
Debt/Equity Negative
ROE Negative
Gross Margin Strong

Read on: Sep 9, 2026 · older than the 27 hours refresh window; not a current reading

How to read these bars and different assessments

Council is a separate blend of available disciplines; MoonshotScore above remains the five-pillar research rating.

Bars show each model's ordered assessment on its own scale, not a probability or a comparable investment return. The adjacent words give the assessment; more filled segments indicate a stronger model reading.

One of these lenses reads this company more favourably than the MoonshotScore does: Griffin-style lens. Each lens is a separate scoring function over its own inputs, so a disagreement is a difference of method rather than a correction — the page's answer stays the MoonshotScore above.

On Sep 9, 2026, the Munger lens read the price at that time as fairly valued against its own estimate of value.

Readings on this page are from Oct 4, 2026, except a card that shows its own read date.

Watch the AXSM film — every key number, told as a short cinematic story

~2 min · open the film

1 · What is it?

What is Axsome Therapeutics (AXSM), and what does it report?

Short answer · as of

Axsome is no longer simply a clinical-stage biotechnology developer.

Research dated 2026-09-13.

Axsome is no longer simply a clinical-stage biotechnology developer. Reported revenue comes from product sales, while its development portfolio seeks additional uses and treatments across central nervous system disorders.

The financial statements therefore capture two businesses at once: a commercial operation building product demand and a research organization funding late-stage programs. Revenue has expanded sharply, but selling and administrative expense now outweighs research spending by a wide margin, making commercial efficiency increasingly important.

Sources (as of 2026-09-13): Business description; Revenue by segment; Annual revenue and net result (USD millions); Quarterly income statement (USD thousands)

2 · Latest results

What do the latest results show for Axsome Therapeutics (AXSM)?

Short answer · as of

The most recent reported quarter, Q2 FY2026, carried revenue of $218M.

Research dated 2026-09-13.

The latest period brought renewed sequential revenue growth, higher gross profit and narrower operating and net losses. Revenue reached the strongest level in the reported quarterly series after a brief pullback, extending the substantial expansion visible in the annual record.

The improvement was not yet clean. Selling and administrative expense continued to climb, operating cash outflow worsened, and the latest reported revenue and loss both fell short of consensus. Higher gross profit and lower research expense helped the accounting loss narrow despite the heavier commercial cost base.

Sources (as of 2026-09-13): Quarterly income statement (USD thousands); Annual revenue and net result (USD millions); Operating cash flow by quarter (USD millions); Reported versus estimated, last 8 quarters; Trailing twelve-month ratio set

Where is operating spending going?

Revenue alongside research and development, selling, general and administrative expenses, and the FMP standardized operating result.

Where is operating spending going? — FMP standardized evidence
Period endRevenueR&DSG&AFMP standardized operating result
Jun 30, 2026Not availableNot availableNot availableNot available
Mar 31, 2026Not availableNot availableNot availableNot available
Dec 31, 2025Not availableNot availableNot availableNot available
Sep 30, 2025Not availableNot availableNot availableNot available

USD. The operating result is the FMP-standardized value supplied by FMP; it may differ from a filing’s GAAP loss from operations when the provider classifies separately presented items differently. It is not net income or cash flow.

Did results meet expectations?

Reported earnings and revenue alongside the estimates recorded by the provider.

Latest report · revenue
$216.35M Aug 10, 2026
Latest report · revenue estimate
$221.11M Aug 10, 2026
Latest report · revenue vs estimate
Below estimate Aug 10, 2026
Latest report · EPS vs estimate
Below estimate Aug 10, 2026
Did results meet expectations? — reported evidence
Report dateRevenue · reportedRevenue · estimateEPS · reportedEPS · estimate
Aug 10, 2026$216.35M$221.11M−$0.9900−$0.8921
May 4, 2026$189.40M$190.91M−$1.2600−$0.8500
Feb 23, 2026$194.69M$193.36M−$0.7100−$0.7000
Nov 3, 2025$170.99M$191.33M−$0.9400−$0.8200

Dates are report dates, not fiscal period ends. Revenue is in USD; EPS is USD per share, rounded to four decimals. The earnings feed does not establish a basic, diluted or adjusted basis. Earnings-feed EPS may differ from statement EPS; the two series are not combined.

Quarterly income statement — 4 quarters
Revenue, net income and earnings per share by quarter
PeriodRevenueNet incomeEPS
Q2 FY2026$218M-$51M-$1.00 (diluted)
Q1 FY2026$191M-$65M-$1.26 (diluted)
Q4 FY2025$196M-$29M-$0.56 (diluted)
Q3 FY2025$171M-$47M-$0.94 (diluted)
3 · Financial strengths and risks

What are the financial strengths and risks for Axsome Therapeutics (AXSM)?

Short answer

Cash and short-term investments were $0.00 at the Jun 30, 2026 balance-sheet date. This figure does not establish a cash runway.

Research dated 2026-09-13.

Liquidity exceeds total debt, leaving Axsome with net cash, and the cash balance has remained within a relatively narrow band across the reported window despite operations consuming cash in most periods. That provides room to fund commercialization and clinical work without an immediate balance-sheet constraint.

The risk sits in the conversion of growth into durable cash generation. Gross margins are high, but selling and administrative spending is rising rapidly, operating losses persist, and the market value stands far above the net cash position. A slowdown in product revenue without a matching adjustment in spending would pressure both the valuation case and the financial cushion.

Sources (as of 2026-09-13): Cash, investments and debt; Cash and investment components; Cash and short-term investments over time (USD millions); Cash decline over the reported window; Operating cash flow by quarter (USD millions); Cash against market value; Quarterly income statement (USD thousands); Trailing twelve-month ratio set

Data-derived red flags

  • Inconsistent delivery — missed Wall Street EPS estimates in 5 of the last 8 reported quarters.
  • Weak fundamentals — a Piotroski F-Score of 3/9 flags soft profitability, leverage or efficiency.
  • Rich valuation — a P/E of 39.83 runs well above the Healthcare sector’s ~21.10x, leaving little room for a miss.
4 · What to check next?

What should you watch next at Axsome Therapeutics (AXSM)?

Short answer · as of

The next earnings report is expected on Nov 2, 2026.

Research dated 2026-09-13.

The upcoming earnings report needs to be read through three linked observations: whether revenue accelerates as consensus expects, whether the loss contracts, and whether operating cash flow begins to follow the improvement in the income statement. Revenue growth accompanied by another sharp increase in commercial expense would be less persuasive than growth that narrows losses and reduces cash use.

Clinical progress also matters because Axsome’s expansion path reaches beyond current product sales. Updates involving depression, Alzheimer’s disease agitation, smoking cessation, migraine, narcolepsy or fibromyalgia could change the breadth of the future portfolio, while delays would leave more of the burden on the existing commercial business.

Sources (as of 2026-09-13): Next earnings report; Reported versus estimated, last 8 quarters; Analyst revenue and earnings estimates (average); Quarterly income statement (USD thousands); Operating cash flow by quarter (USD millions); Business description

What the records here don't tell us

  • No forward revenue or earnings estimate is on file.

Checked against the records this page reads, on the dates shown above.

5 · Peer comparison

How does Axsome Therapeutics compare with its peers?

Short answer

Axsome Therapeutics's score ranks 12th of 13 in the bounded comparison shown, against 12 same-model peers. These are company scores, not expected investment returns. The set lists named competitors first, then companies in the same data-provider industry classification closest in market value; that classification is the provider's, not our judgment of business similarity.

Research dated 2026-09-13.

Axsome differs from a pre-revenue biotechnology developer because product sales already form a substantial and rapidly expanding business. It also differs from a mature specialty pharmaceutical company because continuing losses and a broad late-stage central nervous system pipeline still make research execution and financing discipline central to the story.

That combination produces attractive product gross margins but heavy commercial and development spending. Comparable businesses may depend mainly on trial outcomes or mainly on established brands; Axsome must prove that its commercial platform can fund continued portfolio expansion.

Sources (as of 2026-09-13): Sector / industry (provider taxonomy); Business description; Revenue by segment; Annual revenue and net result (USD millions); Quarterly income statement (USD thousands); Operating cash flow by quarter (USD millions); Trailing twelve-month ratio set

Peer set — price, market value and MoonshotScore
CompanyPriceMarket valueScore
Krystal Biotech, Inc. (KRYS) Same industry, near in market value$322.28 Oct 2, 2026$9.54B97 5-pillar Oct 4, 2026
Bio-Techne Corporation (TECH) Same industry, near in market value$72.40 Oct 2, 2026$11.3B93 5-pillar Oct 4, 2026
Corcept Therapeutics Incorporated (CORT) Same industry, near in market value$116.23 Oct 2, 2026$12.6B91 5-pillar Oct 4, 2026
Caris Life Sciences, Inc. (CAI) Same industry, near in market value$28.30 Oct 2, 2026$8.00B89 5-pillar Oct 4, 2026
Halozyme Therapeutics, Inc. (HALO) Same industry, near in market value$109.86 Oct 2, 2026$13.0B88 5-pillar Oct 4, 2026
Protagonist Therapeutics, Inc. (PTGX) Same industry, near in market value$140.06 Oct 2, 2026$9.01B76 5-pillar Oct 4, 2026
Belite Bio, Inc. (BLTE) Same industry, near in market value$159.56 Oct 2, 2026$6.40B69 5-pillar Oct 4, 2026
TG Therapeutics, Inc. (TGTX) Same industry, near in market value$54.29 Oct 2, 2026$8.31B65 5-pillar Oct 4, 2026
BioMarin Pharmaceutical Inc. (BMRN) Same industry, near in market value$57.18 Oct 2, 2026$11.1B65 5-pillar Oct 4, 2026
Alkermes plc (ALKS) Same industry, near in market value$41.75 Oct 2, 2026$7.00B64 5-pillar Oct 4, 2026
Jazz Pharmaceuticals plc (JAZZ) Named competitor$235.67 Oct 2, 2026$14.8B40 5-pillar Oct 4, 2026
Axsome Therapeutics (AXSM) — this page$179.25$9.39B33
Arrowhead Pharmaceuticals, Inc. (ARWR) Named competitor$64.19 Oct 2, 2026$9.04B30 5-pillar Oct 4, 2026

Only 5-pillar scores are ranked together. Other models are not directly comparable. Price and score dates are shown separately; market-value dates are unavailable.

Screen more Healthcare stocks

The records behind this page

Analyst targets & estimates

What analysts have on file

Price target, low to high
$246.00 – $380.00
Consensus target
$281.63
Median target
$273.50

Consensus record · Captured .

Measured against a quoted price of $179.25 (as of Oct 2, 2026).

Insider activity

Form 4 records via FMP · Of the newest 100 records, those within the last 180 days, newest dated Sep 3, 2026

Transactions
52
Identified insiders
9
Purchases
0
Sales
17
Other transactions
35

Purchases and sales use the reported transaction category. Other transactions include awards, exercises, gifts, withholding and unclassified activity; an acquisition or disposition alone is not a purchase or sale. These records do not establish intent.

What has been published about Axsome Therapeutics (AXSM)?

Read these with our analysis →

Axsome Therapeutics Healthcare Stock: Key Questions Answered

Research dated 2026-09-13; the answers below are from that research, and the full attribution is under Sources. The last 2 questions are answered from this page's own dated data, not from the research.

What does Axsome actually sell while its CNS pipeline advances?

Reported revenue comes from product sales, while the company continues developing treatments across several central nervous system disorders. Its results therefore reflect active commercialization alongside clinical research rather than research spending alone.

Sources (as of 2026-09-13): Revenue by segment; Business description; Quarterly income statement (USD thousands)

Why did Axsome’s latest accounting loss narrow as cash use increased?

Higher gross profit and lower research expense more than offset the rise in selling and administrative spending, narrowing the reported loss. Operating cash outflow nevertheless increased, so the income-statement improvement had not yet translated into stronger cash generation.

Sources (as of 2026-09-13): Quarterly income statement (USD thousands); Operating cash flow by quarter (USD millions)

Can Axsome’s cash position carry its late-stage CNS programs?

Liquidity exceeds debt and cash has been broadly stable across the reported span, providing a meaningful cushion. Operations still consume cash in most periods, so the durability of that cushion depends on product growth eventually producing sustained operating cash.

Sources (as of 2026-09-13): Cash, investments and debt; Cash and short-term investments over time (USD millions); Cash decline over the reported window; Operating cash flow by quarter (USD millions); Business description

Which disorders could expand Axsome beyond its current product revenue?

The development portfolio spans depression, treatment-resistant depression, Alzheimer’s disease agitation, smoking cessation, migraine, narcolepsy and fibromyalgia. Progress across those programs could broaden the commercial base beyond the products generating revenue now.

Sources (as of 2026-09-13): Business description; Revenue by segment

What is the AXSM stock price today?

The last price recorded on this page for Axsome Therapeutics, Inc. (AXSM) is $179.25, as of the Oct 2, 2026 trading session (source: Financial Modeling Prep (FMP) · quote). It is a provider snapshot, not a live exchange feed, so check a brokerage quote before you trade.

What is the AXSM price target?

The analyst consensus price target for Axsome Therapeutics, Inc. (AXSM) is $281.63 (range $246.00 to $380.00, median $273.50), per FMP data captured Oct 4, 2026. Targets are analyst opinions and change often; they are not a Stock Expert AI forecast.

Disclaimer: This content is for informational purposes only and does not constitute investment advice. Always do your own research and consult a financial advisor.

Research written by Codex (gpt-5.6-sol) on 2026-09-13. AI-authored analysis; source dates are shown with each answer. Editorial oversight is systemic, not page-by-page. Editorially accountable: Sedat ANAK, Founder and Editor-in-Chief.

Sources (as of 2026-09-13): Business description; Revenue by segment; Annual revenue and net result (USD millions); Quarterly income statement (USD thousands); Operating cash flow by quarter (USD millions)

Sources — records for every figure on this page (45 figures)

The 45 rows below are exactly the facts the evidence-backed sections of this page printed — the 10-second verdict, the MoonshotScore, price and market value, the five questions with their receipts, and the records behind this page. Known dates and sources are recorded on their own rows; an em dash or UNRECORDED tier preserves a stored observation without inventing either. The quarterly income statement is provider-standardized (FMP) under one row, and scale definitions — a 0-100 rating, the band ladder, the Piotroski 0–9 range — are fixed rather than measured. No number in those sections was generated by a model. The register does not cover quoted third-party headlines, the dated council readings, or the Frequently Asked Questions; each of those says where it came from where it stands.

"As of" is the date the value is true for where the source carries one — a quarter end, a filing date, a price close, the day the score was computed. A cached observation with no source date remains undated; the page publication date is not used as a substitute.

OFFICIAL — 1 fact from SEC filings and earnings calls

OFFICIAL facts used on this page
Fact IDFactValue as shownAs ofTierSource
id.hqSEC filing business addressONE World Trade Center, 29TH Floor, NEW York, NY, 10007OFFICIALSEC EDGAR filer business address — The SEC filer business address. Our market-data provider separately lists "One World Trade Center, New York City, NY, 10007, US".

FMP — 38 facts from Financial Modeling Prep endpoint families

FMP facts used on this page
Fact IDFactValue as shownAs ofTierSource
px.lastLatest provided price$179.25FMPFinancial Modeling Prep (FMP) · quote — Dated to the US trading session the price belongs to, derived from the quote record's timestamp (weekend and pre-open reads roll back to the previous weekday; exchange holidays are not modelled). The record does not establish an exchange execution time. Retrieved 2026-10-04T20:54:57.942Z.
px.changeChange on the day-1.55%FMPFinancial Modeling Prep (FMP) · quote
px.mcapMarket capitalization$9.39BFMPFinancial Modeling Prep (FMP) quote — Provider market cap uses the share class it prices; a company with more than one class may show a larger total elsewhere. Market cap record date: 2026-10-04. Source capture time was not supplied. No share-count basis is inferred; this page preserves the reported amount instead of recalculating it from shares.
earn.nextNext earnings dateNov 2, 2026FMPFinancial Modeling Prep (FMP) earnings calendar — The date is our provider's estimate until the company confirms it.
px.change_absChange on the day, in dollars−$2.82FMPFinancial Modeling Prep (FMP) · quote
fin.q_revenueRevenue, Q2 FY2026$218MFMPFinancial Modeling Prep (FMP) · income statement (quarterly)
px.range5252-week range$117.30–$260.19FMPFinancial Modeling Prep (FMP) quote
px.pePrice / earnings (trailing)39.83FMPFinancial Modeling Prep (FMP) · quote
px.volumeShares traded on the day981.4KFMPFinancial Modeling Prep (FMP) · quote
px.betaBeta0.6FMPFinancial Modeling Prep (FMP) company profile
id.ceoChief executiveHerriot TabuteauFMPFinancial Modeling Prep (FMP) key executives (proxy-derived) — Titles and pay come from the company's proxy statement as our provider parsed it.
id.employeesEmployees1,346FMPFinancial Modeling Prep (FMP) company profile
fin.annualRevenue and net result by fiscal year5 fiscal years, FY1970 through FY2025: FY1970 revenue $0.00, net result $0.00; FY2022 revenue $0.00, net result $0.00; FY2023 revenue $0.00, net result $0.00; FY2024 revenue $0.00, net result $0.00; FY2025 revenue $0.00, net result $0.00FMPFinancial Modeling Prep (FMP), from the company's 10-K income statements
fin.gross_marginGross margin (trailing twelve months)93.2%FMPFinancial Modeling Prep (FMP) key-metrics-ttm + ratios-ttm — A ratio our provider could not compute is absent rather than shown as zero.
earn.history.depth.2026-08-10.revenue_actualRevenue · reported — report date 2026-08-10$216.35MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-08-10.revenue_estimatedRevenue · estimate — report date 2026-08-10$221.11MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-08-10.eps_actualEPS · reported — report date 2026-08-10−$0.9900Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-08-10.eps_estimatedEPS · estimate — report date 2026-08-10−$0.8921Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-05-04.revenue_actualRevenue · reported — report date 2026-05-04$189.40MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-05-04.revenue_estimatedRevenue · estimate — report date 2026-05-04$190.91MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-05-04.eps_actualEPS · reported — report date 2026-05-04−$1.2600Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-05-04.eps_estimatedEPS · estimate — report date 2026-05-04−$0.8500Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-02-23.revenue_actualRevenue · reported — report date 2026-02-23$194.69MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-02-23.revenue_estimatedRevenue · estimate — report date 2026-02-23$193.36MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-02-23.eps_actualEPS · reported — report date 2026-02-23−$0.7100Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2026-02-23.eps_estimatedEPS · estimate — report date 2026-02-23−$0.7000Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2025-11-03.revenue_actualRevenue · reported — report date 2025-11-03$170.99MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2025-11-03.revenue_estimatedRevenue · estimate — report date 2025-11-03$191.33MReport date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2025-11-03.eps_actualEPS · reported — report date 2025-11-03−$0.9400Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
earn.history.depth.2025-11-03.eps_estimatedEPS · estimate — report date 2025-11-03−$0.8200Report date · FMPFinancial Modeling Prep (FMP) earnings — Earnings-history note
fin.q_tableQuarterly income statement4 quarters through Q2 FY2026FMPFinancial Modeling Prep (FMP) · income statement (quarterly), as filed
fin.cash_investmentsCash and short-term investments$0.00FMPFinancial Modeling Prep (FMP), from the company's balance sheet — Long-term investments are shown separately; their marketability is not established by the provider field. The cash and short-term investment balance does not establish unrestricted availability. Long-term investments are excluded and remain unclassified. Restrictions on cash and short-term investments require separate review. The market-value ratio is undefined when the reported amount is zero.
fin.total_debtTotal debt$0.00FMPFinancial Modeling Prep (FMP), from the company's balance sheet — Long-term investments are shown separately; their marketability is not established by the provider field. The cash and short-term investment balance does not establish unrestricted availability.
fin.price_to_bookPrice to book value110.82×FMPFinancial Modeling Prep (FMP) key-metrics-ttm + ratios-ttm — A ratio our provider could not compute is absent rather than shown as zero.
earn.pt_rangeAnalyst price target, low to high$246.00 – $380.00FMPFinancial Modeling Prep (FMP) · price-target consensus — Captured Oct 4, 2026 · Coverage not supplied
earn.pt_consensusConsensus analyst price target$281.63FMPFinancial Modeling Prep (FMP) · price-target consensus — Captured Oct 4, 2026 · Coverage not supplied
earn.pt_medianMedian analyst price target$273.50FMPFinancial Modeling Prep (FMP) · price-target consensus — Captured Oct 4, 2026 · Coverage not supplied
own.insidersInsider transactions via FMP52 transactions · 0 purchases, 17 sales, 35 other transactions · 9 identified insiders · of the newest 100 records, those within the last 180 days, newest dated Sep 3, 2026FMPFinancial Modeling Prep (FMP), carrying Form 4 transaction records — Purchases and sales use the reported transaction category. Other transactions include awards, exercises, gifts, withholding and unclassified activity; an acquisition or disposition alone is not a purchase or sale. These records do not establish intent.

UNRECORDED — 2 facts from stored observations whose source was not recorded

UNRECORDED facts used on this page
Fact IDFactValue as shownAs ofTierSource
earn.historyReported versus estimated, recent quartersEPS beat 3 of 8UNRECORDEDStored earnings-history observation — Captured 2026-10-02 · Expired observation
fin.scoresDistress and quality screensAltman Z 6.07 · Piotroski F 3UNRECORDEDStored financial-scores observation — Captured 2026-10-04

COMPUTED — 2 facts from our arithmetic, formula restated

COMPUTED facts used on this page
Fact IDFactValue as shownAs ofTierSource
earn.history.depth.2026-08-10.revenue_actual.comparisonLatest report · revenue vs estimateBelow estimateReport date · COMPUTEDComputed from Financial Modeling Prep (FMP) earnings — Earnings-history note — Method: compare reported revenue ($216.35M) with the recorded estimate ($221.11M) at displayed precision. Equal displayed values are in line. This compares reported results with recorded estimates, not investment returns.
earn.history.depth.2026-08-10.eps_actual.comparisonLatest report · EPS vs estimateBelow estimateReport date · COMPUTEDComputed from Financial Modeling Prep (FMP) earnings — Earnings-history note — Method: compare reported EPS (−$0.9900) with the recorded estimate (−$0.8921) at displayed precision. Equal displayed values are in line. This compares reported results with recorded estimates, not investment returns.

OURS — 2 facts from Stock Expert AI's own score and rank

OURS facts used on this page
Fact IDFactValue as shownAs ofTierSource
ours.moonshotMoonshotScore v233 of 100 · Weak · pillars 56 / 45 / 44 / 69 / 64OURSStock Expert AI MoonshotScore v2 engine
ours.moonshot_changeMoonshotScore movement33 (stored snapshot Oct 3, 2026) → 33 (current publication computed Oct 4, 2026) (0)OURSStock Expert AI current score publication and immutable score snapshots — The current score publication is not yet represented in the immutable snapshot archive.

Fact-family notes

  1. Earnings-history note. Source series as of 2026-08-10. Dates are report dates, not fiscal period ends. Revenue is in USD; EPS is USD per share, rounded to four decimals. The earnings feed does not establish a basic, diluted or adjusted basis. Earnings-feed EPS may differ from statement EPS; the two series are not combined. Applies to Fact IDs: earn.history.depth.2026-08-10.revenue_actual, earn.history.depth.2026-08-10.revenue_estimated, earn.history.depth.2026-08-10.revenue_actual.comparison, earn.history.depth.2026-08-10.eps_actual.comparison, earn.history.depth.2026-08-10.eps_actual, earn.history.depth.2026-08-10.eps_estimated, earn.history.depth.2026-05-04.revenue_actual, earn.history.depth.2026-05-04.revenue_estimated, earn.history.depth.2026-05-04.eps_actual, earn.history.depth.2026-05-04.eps_estimated, earn.history.depth.2026-02-23.revenue_actual, earn.history.depth.2026-02-23.revenue_estimated, earn.history.depth.2026-02-23.eps_actual, earn.history.depth.2026-02-23.eps_estimated, earn.history.depth.2025-11-03.revenue_actual, earn.history.depth.2025-11-03.revenue_estimated, earn.history.depth.2025-11-03.eps_actual, earn.history.depth.2025-11-03.eps_estimated.
Published
Research standards
Methodology · Editorial policy · Corrections

Sources used for research written 2026-09-13

Historical evidence preserved with this analysis. Current figures are listed separately above.

EvidenceCaptured valueSource dateSource typeSource
Business description
Axsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer's disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation. AXS-07, a novel, orally administered, rapidly-acting investigational medicine that employs multiple mechanisms of action. It has concluded two Phase III studies for the acute treatment of migraine attacks. AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is presently undergoing a Phase III trial for narcolepsy. AXS-14, an oral investigational drug, advancing through Phase III trials for the management of fibromyalgia. Axsome Therapeutics also engages in a research collaboration with Duke University to further assess AXS-05's potential in smoking cessation. The company, established in 2012, has its main offices in New York, New York.
2026-09-13FMPFinancial Modeling Prep (FMP) company profile
Revenue by segment
Product: $633.80M
2025-12-31FMPFinancial Modeling Prep (FMP) revenue segmentation, from the company's 10-K
Annual revenue and net result (USD millions)
Captured record · 5 entries
  • FY2025 — R&D: $183.28M, Revenue: $638.50M, Period end: 2025-12-31, Net result: -$183.17M
  • FY2024 — R&D: $187.08M, Revenue: $385.69M, Period end: 2024-12-31, Net result: -$287.22M
  • FY2023 — R&D: $97.94M, Revenue: $270.60M, Period end: 2023-12-31, Net result: -$239.24M
  • FY2022 — R&D: $57.95M, Revenue: $50.04M, Period end: 2022-12-31, Net result: -$187.13M
  • FY2021 — R&D: $58.06M, Revenue: $0, Period end: 2021-12-31, Net result: -$130.40M
2025-12-31FMPFinancial Modeling Prep (FMP), from the company's 10-K income statements
Quarterly income statement (USD thousands)
Captured record · 8 entries
  • Quarter ended 2026-06-30 — EPS: -$0.99 per share, R&D: $46.23M, SG&A: $208.14M, EPS basic: -$0.99 per share, EPS basis: diluted, Revenue: $218.38M, EPS diluted: -$0.99 per share, Net result: -$51.31M, Gross profit: $204.81M, Operating result: -$49.65M
  • Quarter ended 2026-03-31 — EPS: -$1.26 per share, R&D: $52.68M, SG&A: $185.00M, EPS basic: -$1.26 per share, EPS basis: diluted, Revenue: $191.20M, EPS diluted: -$1.26 per share, Net result: -$64.54M, Gross profit: $176.48M, Operating result: -$63.36M
  • Quarter ended 2025-12-31 — EPS: -$0.56 per share, R&D: $48.79M, SG&A: $169.30M, EPS basic: -$0.56 per share, EPS basis: diluted, Revenue: $196.00M, EPS diluted: -$0.56 per share, Net result: -$28.56M, Gross profit: $183.67M, Operating result: -$29.43M
  • Quarter ended 2025-09-30 — EPS: -$0.94 per share, R&D: $40.16M, SG&A: $150.24M, EPS basic: -$0.94 per share, EPS basis: diluted, Revenue: $170.99M, EPS diluted: -$0.94 per share, Net result: -$47.23M, Gross profit: $159.08M, Operating result: -$46.11M
  • Quarter ended 2025-06-30 — EPS: -$0.97 per share, R&D: $49.54M, SG&A: $130.28M, EPS basic: -$0.97 per share, EPS basis: diluted, Revenue: $150.04M, EPS diluted: -$0.97 per share, Net result: -$47.97M, Gross profit: $136.59M, Operating result: -$36.71M
  • Quarter ended 2025-03-31 — EPS: -$1.22 per share, R&D: $44.78M, SG&A: $120.79M, EPS basic: -$1.22 per share, EPS basis: diluted, Revenue: $121.46M, EPS diluted: -$1.22 per share, Net result: -$59.41M, Gross profit: $111.67M, Operating result: -$56.98M
  • Quarter ended 2024-12-31 — EPS: -$1.54 per share, R&D: $55.01M, SG&A: $113.27M, EPS basic: -$1.54 per share, EPS basis: diluted, Revenue: $118.77M, EPS diluted: -$1.54 per share, Net result: -$74.91M, Gross profit: $108.25M, Operating result: -$72.62M
  • Quarter ended 2024-09-30 — EPS: -$1.34 per share, R&D: $45.39M, SG&A: $95.56M, EPS basic: -$1.34 per share, EPS basis: diluted, Revenue: $104.76M, EPS diluted: -$1.34 per share, Net result: -$64.60M, Gross profit: $96.33M, Operating result: -$62.62M
2026-06-30FMPFinancial Modeling Prep (FMP), from the company's 10-Q and 10-K income statements
Operating cash flow by quarter (USD millions)
Captured record · 8 entries
  • Quarter ended 2026-06-30 — Capital expenditure: $120,000, Operating cash flow: -$32.95M
  • Quarter ended 2026-03-31 — Capital expenditure: -$120,000, Operating cash flow: -$20.70M
  • Quarter ended 2025-12-31 — Capital expenditure: -$70,000, Operating cash flow: -$18.65M
  • Quarter ended 2025-09-30 — Capital expenditure: -$60,000, Operating cash flow: $1.05M
  • Quarter ended 2025-06-30 — Capital expenditure: -$10,000, Operating cash flow: -$32.42M
  • Quarter ended 2025-03-31 — Capital expenditure: -$340,000, Operating cash flow: -$43.37M
  • Quarter ended 2024-12-31 — Capital expenditure: -$30,000, Operating cash flow: -$26.20M
  • Quarter ended 2024-09-30 — Capital expenditure: $150,000, Operating cash flow: -$18.63M
2026-06-30FMPFinancial Modeling Prep (FMP), from the company's 10-Q cash-flow statements
Reported versus estimated, last 8 quarters
Captured record · 8 entries
  • Reported 2026-08-10 — EPS actual: -$0.99 per share, EPS estimated: -$0.89205 per share, Revenue actual: $216.35M, Revenue estimated: $221.11M
  • Reported 2026-05-04 — EPS actual: -$1.26 per share, EPS estimated: -$0.85 per share, Revenue actual: $189.40M, Revenue estimated: $190.91M
  • Reported 2026-02-23 — EPS actual: -$0.71 per share, EPS estimated: -$0.7 per share, Revenue actual: $194.69M, Revenue estimated: $193.36M
  • Reported 2025-11-03 — EPS actual: -$0.94 per share, EPS estimated: -$0.82 per share, Revenue actual: $170.99M, Revenue estimated: $191.33M
  • Reported 2025-08-04 — EPS actual: -$0.92 per share, EPS estimated: -$1 per share, Revenue actual: $150.04M, Revenue estimated: $140.02M
  • Reported 2025-05-05 — EPS actual: -$1.22 per share, EPS estimated: -$1.26 per share, Revenue actual: $121.46M, Revenue estimated: $119.16M
  • Reported 2025-02-18 — EPS actual: -$1.54 per share, EPS estimated: -$1 per share, Revenue actual: $118.77M, Revenue estimated: $118.07M
  • Reported 2024-11-12 — EPS actual: -$1.34 per share, EPS estimated: -$1.38 per share, Revenue actual: $104.76M, Revenue estimated: $98.37M
2026-08-10FMPFinancial Modeling Prep (FMP) earnings
Trailing twelve-month ratio set
Quick ratio: 1.34; Current ratio: 1.43; Debt to equity: 2.63; Net margin: -24.7%; Gross margin: 93.2%; Operating margin: -24.3%; Return on assets: -25.2%; Return on equity: -255.6%

Price-based multiples captured at research time are not repeated here; the page shows each once, from current figures with their own dates. A ratio our provider could not compute is absent rather than shown as zero.

2026-09-13FMPFinancial Modeling Prep (FMP) key-metrics-ttm + ratios-ttm
Cash, investments and debt
Total debt: $219.21M; Liquidity basis: cash and short-term investments; Total liabilities: $678.14M; Cash and short-term investments: $319.85M; Cash and investments: $319.90M; Long-term investments: $0; Long-term investments classification: unclassified

Long-term investments are shown separately; their marketability is not established by the provider field. The cash and short-term investment balance does not establish unrestricted availability.

2026-06-30FMPFinancial Modeling Prep (FMP), from the company's balance sheet
Cash and investment components
Total basis: cash short and long-term investments; Total: $319.90M; Cash and short-term investments: $319.90M; Long-term investments: $0; Long-term investments classification: unclassified

Sums the balance sheet's cash and short-term investments with its long-term investments.; The long-term investment field does not establish marketability; the sum is not a measure of available liquidity.; These provider fields do not establish investment access restrictions or explain differences from third-party cash figures.

2026-06-30COMPUTEDComputed from the balance sheet
Cash and short-term investments over time (USD millions)
Captured record · 8 entries
  • 2026-06-30 — Amount: $319.90M, Cash basis: cash and short-term investments
  • 2026-03-31 — Amount: $305.10M, Cash basis: cash and short-term investments
  • 2025-12-31 — Amount: $322.90M, Cash basis: cash and short-term investments
  • 2025-09-30 — Amount: $325.30M, Cash basis: cash and short-term investments
  • 2025-06-30 — Amount: $303.00M, Cash basis: cash and short-term investments
  • 2025-03-31 — Amount: $300.90M, Cash basis: cash and short-term investments
  • 2024-12-31 — Amount: $315.40M, Cash basis: cash and short-term investments
  • 2024-09-30 — Amount: $327.30M, Cash basis: cash and short-term investments
2026-06-30FMPFinancial Modeling Prep (FMP), from the company's quarterly balance sheets
Cash decline over the reported window
To: 2026-06-30; From: 2024-09-30; Periods: 7; Cash basis: cash and short-term investments; Closing balance: $319.90M; Decline: $7.50M; Opening balance: $327.30M; Average change per period: $1.10M

Change in cash, cash equivalents and short-term investments between the 2024-09-30 and 2026-06-30 balance sheets.; This is a balance change, not operating burn: financing and investing move it too.; Averaged over 7 reporting periods of unequal length.

2026-06-30COMPUTEDComputed from reported balances
Cash against market value
As of: 2026-06-30; Cash basis: cash and short-term investments; Net cash: $100.60M; Total debt: $219.20M; Cash and investments: $319.90M

Price-based multiples captured at research time are not repeated here; the page shows each once, from current figures with their own dates. Cash is the latest reported cash and short-term investment balance; long-term investments are excluded. Market capitalization is the latest provider value.; The reported balance does not establish unrestricted availability or liquidation value.; The two are measured on different dates — the balance sheet is a quarter-end, the market cap is a recent close.; Debt is total debt as reported, including operating lease liabilities where the filer includes them.

2026-06-30COMPUTEDComputed from the balance sheet and the latest market capitalization
Next earnings report
Date: 2026-11-02; EPS estimate: -$0.48897 per share; Revenue estimate: $258.28M

The date is our provider's estimate until the company confirms it.

2026-09-13FMPFinancial Modeling Prep (FMP) earnings calendar
Analyst revenue and earnings estimates (average)
Captured record · 4 entries
  • FY2027 — EPS average: $4.66 per share, Revenue average: $1.56B, Revenue low: $1.19B, Revenue high: $1.80B, Analysts (revenue): 16
  • FY2028 — EPS average: $12.56 per share, Revenue average: $2.24B, Revenue low: $1.67B, Revenue high: $2.78B, Analysts (revenue): 17
  • FY2029 — EPS average: $22.27 per share, Revenue average: $3.07B, Revenue low: $2.56B, Revenue high: $3.47B, Analysts (revenue): 13
  • FY2030 — EPS average: $29.8 per share, Revenue average: $3.80B, Revenue low: $3.17B, Revenue high: $4.30B, Analysts (revenue): 8
2026-09-13FMPFinancial Modeling Prep (FMP) analyst estimates
Sector / industry (provider taxonomy)
Healthcare / Biotechnology

The company's SEC filings classify it under SIC 2834 — Pharmaceutical Preparations.

2026-09-13FMPFinancial Modeling Prep (FMP) company profile
Data Sources & Methodology
Figures come from Financial Modeling Prep (FMP). If FMP has no figure for a ticker, a price or fundamental may come from a Yahoo Finance fallback, or a price from an Alpaca fallback. SEC EDGAR is used only for filing links and company identity details (legal name, address), never for figures. AI analysis by Stock Expert AI proprietary algorithms. Technical indicators via industry-standard calculations. Last updated: .
Data Provenance
Sources: Financial Modeling Prep (FMP) — Primary · Yahoo Finance — Fallback · Alpaca — Tertiary
Last fetched:
Cache TTL: Quote 5min · Profile 7d · Financials 7d · Insider 48h
How we use AI: Numbers are pulled directly from FMP & Yahoo Finance — our AI writes the analysis, it never edits the figures.
Data provided as-is for educational purposes. Not financial advice. Methodology

Data provided for informational purposes only.

ETFs that hold AXSM

Funds in our ETF coverage that list AXSM among the top 10 holdings on their fund page, largest weight first. Each weight is the fund's reported holding weight as of the date in its row.

ETFWeightHoldings as of
iShares Neuroscience and Healthcare ETF (IBRN)4.53%