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ProShares - UltraShort Nasdaq Biotechnology (BIS) Fund Overview

Educational signal · not a buy or sell recommendation · How to read this

$11.71 +$0.0745 (+0.64%)
Vol: 4.4K|
Data from FMP · Methodology

For informational purposes only. Not financial advice. Machine-generated analysis by Stock Expert AI — model gemini-2.0-flash, generated Mar 17, 2026. Editorial oversight is systemic, not page-by-page. Editorially accountable: Sedat ANAK, Founder and Editor-in-Chief. Data sources: Financial Modeling Prep, Yahoo Finance, SEC EDGAR

Quick Answer

ProShares - UltraShort Nasdaq Biotechnology (BIS) trades at $11.71. ProShares UltraShort Nasdaq Biotechnology (BIS) is an exchange-traded fund (ETF) designed to deliver twice the inverse of the daily performance of the Nasdaq Biotechnology Index. Sector: Financials.

Price as of · Last analyzed: Mar 17, 2026
ProShares UltraShort Nasdaq Biotechnology (BIS) is an exchange-traded fund (ETF) designed to deliver twice the inverse of the daily performance of the Nasdaq Biotechnology Index. It provides investors with a tool to potentially profit from, or hedge against, declines in the biotechnology sector.

Analyst Coverage for BIS: BIS does not currently have published analyst price targets in our coverage universe. This is common for smaller-cap names with limited Wall Street coverage.

▶ Watch the BIS film Every key number, told as a short cinematic story — just press play. ~2 min

ProShares - UltraShort Nasdaq Biotechnology (BIS) Financial Services Profile

IPO Year2010

ProShares UltraShort Nasdaq Biotechnology (BIS) offers a leveraged inverse exposure to the Nasdaq Biotechnology Index, targeting sophisticated investors seeking short-term hedging or speculative opportunities within the volatile biotech sector. It is important to understand the risks associated with leveraged and inverse ETFs before investing.

Data Provenance | Financial Data Quantitative Analysis Analysis: Mar 17, 2026

What Is the Investment Thesis for BIS?

AI-written as of Mar 17, 2026 — figures and tone reflect the data available then, not today's score.

BIS presents a tactical opportunity for investors with a short-term bearish outlook on the biotechnology sector. By providing -2x daily inverse exposure to the Nasdaq Biotechnology Index, BIS can generate gains when the index declines. However, the leveraged nature of the fund amplifies both gains and losses, making it a high-risk investment. Investors should closely monitor the biotech sector and be prepared to actively manage their positions. The fund's performance is highly sensitive to daily market movements, and its suitability for long-term investment is questionable due to the effects of compounding and volatility. A key consideration is the potential for rapid erosion of capital if the Nasdaq Biotechnology Index moves against the intended direction.

Based on FMP financials and quantitative analysis

BIS Key Highlights

AI-written as of Mar 17, 2026 — figures and tone reflect the data available then, not today's score.

BIS seeks daily investment results that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index.

  • The fund is designed for short-term tactical positioning rather than long-term investment strategies.
  • BIS is managed by ProShare Advisors LLC, a leading provider of alternative ETFs.
  • The fund's beta is -1.47, indicating a high degree of inverse correlation with the Nasdaq Biotechnology Index.
  • BIS does not offer a dividend yield, as its primary objective is to provide leveraged inverse exposure.

Who Are BIS's Competitors?

BIS is benchmarked below against 8 industry peers on price, market cap, and our AI MoonshotScore.

Company Price Change Market Cap MoonshotScore
BULG Leverage Shares 2x Long BULL Daily ETF $34.97 +9.12% —
BLK BlackRock, Inc. $1059.63 -0.44% $164B —
BX Blackstone Inc. $111.74 -0.45% $135B —
APOS Apollo Global Management, Inc. $25.59 -0.23% $74.8B —
BAM Brookfield Asset Management $44.85 +0.65% $71.6B —
AMP Ameriprise Financial, Inc. $490.91 -0.79% $44.1B —
ARES Ares Management Corporation $117.55 +0.84% $38.6B —
TROW T. Rowe Price Group, Inc. $104.62 -1.14% $22.4B —

AI Score by Stock Expert AI · Price data: FMP / Yahoo Finance

What Are BIS's Key Strengths?

Provides a convenient way to gain leveraged inverse exposure to the Nasdaq Biotechnology Index.

  • Offers a tool for hedging against potential losses in biotech portfolios.
  • Managed by ProShare Advisors LLC, a reputable provider of alternative ETFs.
  • High inverse correlation with the Nasdaq Biotechnology Index, as indicated by its beta.

What Are BIS's Weaknesses?

Leveraged nature amplifies both gains and losses, making it a high-risk investment.

  • Not suitable for long-term investment due to the effects of compounding and volatility.
  • Performance is highly sensitive to daily market movements.
  • Subject to management fees and expenses, which can reduce returns.

What Are the Key Risks for BIS?

The leveraged nature of BIS amplifies both gains and losses, making it a high-risk investment.

  • The fund is not suitable for long-term investment due to the effects of compounding and volatility.
  • Unexpected positive developments in the biotechnology sector could lead to losses.
  • Changes in regulations governing leveraged and inverse ETFs could impact its operations.
  • Competition from other similar products could reduce its market share.

What Are BIS's Competitive Advantages?

  • Brand recognition and reputation of ProShares as a leading provider of alternative ETFs.
  • Established track record of providing leveraged and inverse exposure to various indices.
  • Expertise in managing complex financial instruments and derivatives.
  • First-mover advantage in offering a leveraged inverse ETF focused on the Nasdaq Biotechnology Index.

What Does BIS Do?

ProShares UltraShort Nasdaq Biotechnology (BIS) is an exchange-traded fund (ETF) managed by ProShare Advisors LLC. It was created to provide investors with a way to achieve daily investment results, before fees and expenses, that correspond to two times the inverse (-2x) of the daily performance of the Nasdaq Biotechnology Index. This index comprises a selection of securities listed on the NASDAQ that are classified as biotechnology companies, making BIS a specialized tool for those with a view on the short-term direction of the biotech market. The fund is not designed for long-term investing and is best suited for sophisticated investors who understand the risks associated with leveraged and inverse ETFs. These types of funds can experience significant volatility and may not perform as expected if held for longer than a single day due to the effects of compounding. ProShares, as a company, is a leading provider of alternative ETFs, offering a range of products designed to help investors manage risk and enhance returns. Their focus is on providing tools that allow investors to express specific market views, whether bullish, bearish, or neutral.

What Products and Services Does BIS Offer?

  • Provides leveraged inverse exposure to the Nasdaq Biotechnology Index.
  • Offers a tool for investors to profit from declines in the biotechnology sector.
  • Allows investors to hedge against potential losses in their biotech portfolios.
  • Seeks daily investment results that are two times the inverse of the index's performance.
  • Provides short-term tactical investment opportunities.
  • Offers a way to express a bearish view on the biotechnology market.

How Does BIS Make Money?

  • Generates revenue through management fees charged on the assets under management (AUM).
  • Aims to track the daily performance of two times the inverse of the Nasdaq Biotechnology Index.
  • Utilizes derivatives and other financial instruments to achieve its investment objective.
  • Rebalances its portfolio daily to maintain the desired leverage ratio.

What Industry Does BIS Operate In?

The asset management industry is highly competitive, with numerous firms offering a wide range of investment products, including ETFs. Inverse and leveraged ETFs like BIS cater to a niche market of sophisticated investors seeking to express short-term market views. The biotechnology sector itself is characterized by high growth potential but also significant volatility due to factors such as clinical trial outcomes, regulatory approvals, and patent expirations. BIS provides a tool for investors to potentially profit from or hedge against this volatility. Competitors offer similar leveraged and inverse products across various sectors and asset classes.

Who Are BIS's Key Customers?

  • Sophisticated investors seeking short-term tactical opportunities.
  • Hedge funds and other institutional investors.
  • Financial advisors managing client portfolios.
  • Traders looking to profit from short-term declines in the biotechnology sector.
Model self-rating on this text: 83% (not a measure of the evidence) Updated: Mar 17, 2026

Research confidence

Low

Thin evidence — scoring coverage unknown. Treat this as a starting point, not a conclusion.

  • ● Scoring coverage unknown
  • ● Price is current
  • ● No filing on record
  • ● No analyst coverage
  • ● This is an etf, not an operating company

MoonshotScore History

Recorded daily since 2026-08-23 · 41 snapshots

2026-08-23 47
2026-08-31 47
2026-09-08 47
2026-09-16 47
2026-09-24 47
2026-10-04 47

What changed?

The score has stayed at 47.

Over the same 30 days the stock moved +6.6%.

BIS Financials

Bull Case vs Bear Case

Bull Case

  • Provides a convenient way to gain leveraged inverse exposure to the Nasdaq Biotechnology Index.
  • Offers a tool for hedging against potential losses in biotech portfolios.
  • Managed by ProShare Advisors LLC, a reputable provider of alternative ETFs.
  • High inverse correlation with the Nasdaq Biotechnology Index, as indicated by its beta.

Bear Case

  • Leveraged nature amplifies both gains and losses, making it a high-risk investment.
  • Not suitable for long-term investment due to the effects of compounding and volatility.
  • Performance is highly sensitive to daily market movements.
  • Subject to management fees and expenses, which can reduce returns.

AI-generated arguments based on insider flow, news sentiment and technicals — not financial advice · March 2026

BIS Latest News

No recent news available for BIS.

BIS Analyst Consensus

Consensus Rating

Aggregated Buy/Hold/Sell recommendations collected by Financial Modeling Prep for BIS.

Price Targets

Wall Street price target analysis for BIS.

BIS MoonshotScore

MoonshotScore is Stock Expert AI's proprietary 0-100 research rating, not a buy or sell recommendation. No MoonshotScore is published for BIS; grades run from A+ (80-100) to F (below 30).

BIS Financials Stock FAQ

How does BIS perform in different market conditions?

BIS is designed to perform well when the Nasdaq Biotechnology Index declines. In a falling market, BIS should generate positive returns, although the actual returns may differ from the stated -2x leverage due to factors such as fees, expenses, and daily rebalancing. However, in a rising market, BIS is expected to lose value.

Disclaimer: This content is for informational purposes only and does not constitute investment advice. Always do your own research and consult a financial advisor.

Official Resources

Price as of Analysis updated

MoonshotScore is not published for this security.

Data Sources & Methodology
Figures come from Financial Modeling Prep (FMP). If FMP has no figure for a ticker, a price or fundamental may come from a Yahoo Finance fallback, or a price from an Alpaca fallback. SEC EDGAR is used only for filing links and company identity details (legal name, address), never for figures. AI analysis by Stock Expert AI proprietary algorithms. Technical indicators via industry-standard calculations. Last updated: .
Data Provenance
Sources: Financial Modeling Prep (FMP) — Primary · Yahoo Finance — Fallback · Alpaca — Tertiary
Last fetched:
Cache TTL: Quote 5min · Profile 7d · Financials 7d · Insider 48h
How we use AI: Numbers are pulled directly from FMP & Yahoo Finance — our AI writes the analysis, it never edits the figures.
Data provided as-is for educational purposes. Not financial advice. Methodology

Data provided for informational purposes only.

Analysis Notes
  • Leveraged and inverse ETFs are complex financial instruments and are not suitable for all investors.
  • Past performance is not indicative of future results.
Data Sources
Financial Modeling Prep (FMP)Stock Expert AI proprietary analysis