Dyadic International, Inc. (DYAI)

Dyadic International, Inc. is a biotechnology company focused on developing and selling enzymes and proteins. Their patented C1 platform is used for manufacturing human and animal vaccines and drugs.

51/100 AI Score MCap $29.02M Vol 21.9K

Company Overview

CEOMark A. Emalfarb
Employees6
HeadquartersJupiter, FL, US
IPO Year2008

Dyadic International leverages its innovative C1 platform for efficient protein production, targeting the development of vaccines and therapeutics; a compelling opportunity for investors seeking exposure to disruptive biotechnology with a focus on addressing unmet needs in human and animal health.

Investment Thesis

Dyadic International presents a compelling investment opportunity due to its innovative C1 platform, which offers a potentially disruptive approach to biologics manufacturing. The successful validation of DYAI-100 in Phase 1 clinical trials could serve as a significant catalyst, demonstrating the platform's ability to produce effective vaccines against COVID-19 variants. The company's collaborations with VTT, Biotechnology Developments for Industry in Pharmaceuticals, and Syngene International further enhance its R&D capabilities and expand its market reach. With a market capitalization of $0.03 billion, Dyadic offers substantial upside potential if it can successfully commercialize its C1 platform and secure additional partnerships. The company's gross margin of 42.2% indicates a strong potential for profitability as it scales its operations.

Key Highlights

  • Market capitalization of $0.03 billion, indicating potential for growth if the C1 platform is successfully commercialized.
  • Gross margin of 42.2% demonstrates the potential for strong profitability as the company scales its operations.
  • DYAI-100, a SARS-CoV-2-RBD antigen vaccine candidate, is currently in Phase 1 clinical trials, representing a key milestone for the company.
  • Research and development agreements with VTT Technical Research Centre of Finland, Ltd., expanding the company's research capabilities.
  • Collaboration with Syngene International Limited, enhancing the company's ability to develop and commercialize its products.

Competitors

Strengths

  • Patented C1 protein production platform.
  • Efficient and cost-effective protein production.
  • Experienced management team.
  • Strategic partnerships.

Weaknesses

  • Limited financial resources.
  • Dependence on C1 platform.
  • Early stage of development.
  • Small number of employees.

Catalysts

  • Upcoming: Completion of Phase 1 clinical trials for DYAI-100.
  • Ongoing: Expansion of C1 platform applications.
  • Ongoing: Strategic partnerships and collaborations.
  • Ongoing: Licensing of C1 platform to other companies.

Risks

  • Potential: Clinical trial failures.
  • Potential: Competition from established biotechnology companies.
  • Potential: Regulatory hurdles.
  • Ongoing: Limited financial resources.
  • Potential: Intellectual property infringement.

Growth Opportunities

  • Expansion of C1 Platform Applications: Dyadic can expand the applications of its C1 platform beyond COVID-19 vaccines to develop a broader range of biologics, including monoclonal antibodies, biosimilars, and other therapeutic proteins. The global market for biologics is projected to reach $420 billion by 2028, providing a significant growth opportunity for Dyadic. Timeline: Ongoing.
  • Strategic Partnerships and Collaborations: Dyadic can pursue additional strategic partnerships and collaborations with pharmaceutical companies and research institutions to accelerate the development and commercialization of its products. These partnerships can provide access to funding, expertise, and market channels. Timeline: Ongoing.
  • Geographic Expansion: Dyadic can expand its geographic presence by establishing operations in key markets, such as Europe and Asia. This will allow the company to tap into new customer segments and increase its revenue streams. Timeline: 2027-2028.
  • Development of Animal Health Products: Dyadic can leverage its C1 platform to develop and commercialize animal health products, including vaccines and therapeutics for livestock and companion animals. The global animal health market is estimated to reach $50 billion by 2027, representing a significant growth opportunity for Dyadic. Timeline: 2026-2027.
  • Licensing of C1 Platform: Dyadic can license its C1 platform to other biotechnology companies and research institutions, generating revenue and expanding the reach of its technology. This can provide a recurring revenue stream and reduce the company's reliance on product sales. Timeline: Ongoing.

Opportunities

  • Expanding applications of C1 platform.
  • Strategic partnerships and collaborations.
  • Geographic expansion.
  • Development of animal health products.

Threats

  • Competition from established biotechnology companies.
  • Regulatory hurdles.
  • Clinical trial failures.
  • Intellectual property infringement.

Competitive Advantages

  • Patented C1 protein production platform.
  • Efficient and cost-effective protein production capabilities.
  • Expertise in developing and manufacturing biologics.
  • Strategic partnerships with leading research institutions and pharmaceutical companies.

About

Dyadic International, Inc., founded in 1979 and headquartered in Jupiter, Florida, is a biotechnology platform company dedicated to the development, production, and sale of enzymes and other proteins. The company's core technology is its patented and proprietary C1 platform, a fungal expression system that enables the efficient and cost-effective production of a wide range of biologics. This platform is utilized for research, development, and commercial activities focused on manufacturing human and animal vaccines and drugs, including virus-like particles and antigens, monoclonal antibodies, bi/tri-specific antibodies, fab antibody fragments, Fc-fusion proteins, biosimilars and/or biobetters, and other therapeutic enzymes and proteins. Dyadic's lead product candidate is DYAI-100, a SARS-CoV-2-RBD antigen vaccine candidate currently in Phase 1 clinical trials. This trial aims to validate the C1 platform as a viable solution for developing next-generation multivariant COVID-19 vaccines. Dyadic collaborates with various organizations, including VTT Technical Research Centre of Finland, Ltd., Biotechnology Developments for Industry in Pharmaceuticals, S.L.U., and Syngene International Limited, to expand its research and development capabilities and accelerate the commercialization of its products.

What They Do

  • Develops and produces enzymes and other proteins.
  • Utilizes the patented C1 platform for protein production.
  • Conducts research and development for human and animal vaccines and drugs.
  • Manufactures virus-like particles and antigens.
  • Develops monoclonal antibodies and other therapeutic proteins.
  • Offers DYAI-100, a SARS-CoV-2-RBD antigen vaccine candidate.

Business Model

  • Develops and licenses its C1 protein production platform.
  • Generates revenue through research and development agreements.
  • Aims to commercialize vaccines and therapeutic proteins.
  • Partners with other companies for manufacturing and distribution.

Industry Context

Dyadic International operates in the biotechnology industry, a sector characterized by rapid innovation and significant growth potential. The market for biologics, including vaccines and therapeutic proteins, is expanding due to the increasing prevalence of chronic diseases and the growing demand for personalized medicine. The competitive landscape includes established pharmaceutical companies and emerging biotechnology firms, all vying for market share. Dyadic's C1 platform offers a unique value proposition by enabling more efficient and cost-effective production of biologics compared to traditional methods. This positions Dyadic to capitalize on the growing demand for affordable and accessible healthcare solutions.

Key Customers

  • Pharmaceutical companies seeking efficient protein production.
  • Biotechnology companies developing vaccines and therapeutics.
  • Research institutions conducting biological research.
  • Animal health companies developing animal vaccines and therapeutics.
AI Confidence: 69% Updated: 2/8/2026

Financials

Recent Quarterly Results

Quarter Revenue Net Income EPS
Q3 2025 $1M -$2M $-0.06
Q2 2025 $463,449 -$2M $-0.06
Q1 2025 $183,100 -$2M $-0.07
Q4 2024 $817,376 -$2M $-0.05

Source: Company filings

Chart & Info

Price Chart

Dyadic International, Inc. (DYAI) stock price: $0.80 (+0.00, +0.00%)

Why Bull

  • Recent insider buying suggests confidence in Dyadic's future prospects, aligning interests with shareholders.
  • The community is buzzing about potential partnerships leveraging Dyadic's C1 platform for novel applications.
  • Positive sentiment indicates the market is receptive to Dyadic's focus on sustainable protein production.
  • The narrative around biotech innovation is strong, potentially benefiting companies like Dyadic.

Why Bear

  • Lack of concrete partnership announcements leaves some investors skeptical about immediate revenue generation.
  • Community concerns linger regarding the scalability of Dyadic's technology to meet large-scale demand.
  • Market perception may be influenced by broader economic uncertainty impacting smaller biotech companies.
  • Bearish sentiment stems from the long development timelines inherent in the biotech industry, requiring patience.

Latest News

Technical Analysis

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Rationale

AI-generated technical analysis for DYAI including trend direction, momentum, and pattern recognition.

What to Watch

Key support and resistance levels, volume signals, and upcoming events.

Risk Management

Position sizing, stop-loss levels, and risk-reward assessment.

Community

Discussion

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Sentiment

Community sentiment and discussion activity for DYAI.

Make a Prediction

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Current price: $0.80

Analyst Consensus

Consensus Rating

Aggregated Buy/Hold/Sell recommendations from Benzinga, Yahoo Finance, and Finnhub for DYAI.

Price Targets

Wall Street price target analysis for DYAI.

Insider Flow (30d)

TCHELET RONEN
Insider
1 month ago
BOUGHT
98,147 shares
Rawson Ping Wang
Insider
1 month ago
BOUGHT
217,401 shares
Lucy Patrick K.
Insider
1 month ago
BOUGHT
179,705 shares
Kaye Jack
Insider
1 month ago
BOUGHT
188,595 shares
HERBST SETH
Insider
1 month ago
BOUGHT
292,205 shares
Hazelton Joseph P
Insider
1 month ago
BOUGHT
259,008 shares
EMALFARB MARK A
Insider
1 month ago
BOUGHT
4,958,667 shares

MoonshotScore

50.5/100

Score Factors

  • Revenue Growth 6/100

    Revenue increased 20.6% YoY, reflecting moderate but steady business growth.

  • Gross Margin 6/100

    Gross margin of 31.5% is acceptable but leaves limited room for R&D and marketing investment.

  • Operating Leverage 6/100

    Revenue growth is driving operating leverage, meaning profits can grow faster than costs.

  • Cash Runway 5/100

    Cash position data is currently unavailable for this company.

  • R&D Intensity 5/100

    R&D spending data is currently unavailable for this company.

  • Insider Activity 6/100

    No significant insider buying or selling recently, which is neutral for the stock outlook.

  • Short Interest 5/100

    Float and volume data unavailable for liquidity analysis.

  • Price Momentum 0/100

    No bullish technical signals detected. The stock lacks upward price momentum currently.

  • News Sentiment 5/100

    No sentiment data available

What does this score mean?

The MoonshotScore rates DYAI's growth potential on a scale of 0-100 across multiple factors including innovation, market disruption, financial health, and momentum.

Frequently Asked Questions

What does Dyadic International, Inc. do?

Dyadic International is a biotechnology company that specializes in the development and production of enzymes and other proteins using its patented C1 platform. This platform enables the efficient and cost-effective manufacturing of biologics, including vaccines and therapeutic proteins. The company focuses on developing solutions for both human and animal health, with its lead product candidate, DYAI-100, being a SARS-CoV-2-RBD antigen vaccine. Dyadic aims to partner with pharmaceutical companies and research institutions to commercialize its products and expand the reach of its C1 platform.

Is DYAI stock a good buy?

DYAI stock presents a speculative investment opportunity with high potential upside and significant risks. The company's C1 platform offers a unique value proposition in the biologics manufacturing space, but its success depends on the successful completion of clinical trials and commercialization of its products. With a market capitalization of $0.03 billion and negative P/E ratio of -4.00, DYAI is a high-risk, high-reward investment. Investors should carefully consider their risk tolerance and conduct thorough due diligence before investing in DYAI.

What are the main risks for DYAI?

The main risks for Dyadic International include the potential for clinical trial failures, competition from established biotechnology companies, regulatory hurdles, and limited financial resources. The company's success depends on the successful development and commercialization of its products, which is subject to significant regulatory and clinical risks. Additionally, Dyadic faces competition from larger and more established biotechnology companies with greater financial resources. The company's limited financial resources also pose a risk to its ability to fund its research and development activities.

Is DYAI a good stock to buy?

Whether DYAI is a good investment depends on your financial goals, risk tolerance, and investment horizon. Key factors to evaluate include the company's revenue growth trajectory, profit margins, debt-to-equity ratio, competitive moat, and valuation multiples (P/E, P/S, EV/EBITDA) relative to industry peers. Our AI-generated Investment Thesis and SWOT analysis on this page provide a data-driven starting point. Always do your own research and consider consulting a financial advisor before making investment decisions.

What is the DYAI MoonshotScore?

The MoonshotScore for DYAI is an AI-powered rating from 0 to 100 that evaluates a stock across four dimensions: growth potential (revenue and earnings trajectory), financial health (balance sheet strength, cash flow), market momentum (price trends, volume patterns, institutional flows), and risk factors (volatility, debt levels, sector headwinds). Scores above 70 indicate strong potential, 50-70 moderate, and below 50 suggests caution. The score is recalculated daily using the latest financial data and market signals.

How often is DYAI data updated?

DYAI stock prices are updated in real-time during U.S. market hours (9:30 AM - 4:00 PM ET, Monday through Friday). After-hours and pre-market prices are also tracked. Company fundamentals (earnings, revenue, balance sheet) are refreshed when new quarterly or annual reports are filed. Analyst ratings, price targets, and AI-generated insights are updated daily. Breaking news related to DYAI is aggregated continuously from premium financial news sources throughout the day.

What are the growth catalysts for DYAI?

Growth catalysts for Dyadic International, Inc. (DYAI) can include several categories: product catalysts (new launches, FDA approvals, patent grants), financial catalysts (earnings beats, margin expansion, share buybacks), strategic catalysts (acquisitions, partnerships, market expansion into new regions), and macro catalysts (favorable regulation, industry tailwinds, secular growth trends). Our AI analyzes Dyadic International, Inc.'s specific catalysts using earnings transcripts, SEC filings, and news sentiment to identify the most impactful near-term and long-term drivers.

Who are DYAI's main competitors?

Dyadic International, Inc. (DYAI) competes with companies in its industry that target similar customers, markets, or product categories. Competitor analysis involves comparing key metrics: market share, revenue growth rates, profit margins, R&D spending, and valuation multiples. Understanding competitive positioning helps investors assess whether DYAI has a sustainable competitive advantage (moat) through brand strength, network effects, cost leadership, or switching costs. Our Competitors section provides a side-by-side comparison with relevant peers.

What do analysts say about DYAI?

Wall Street analyst coverage for DYAI includes consensus ratings (buy, hold, or sell), 12-month price targets, and earnings estimates. Analyst opinions are aggregated from major investment banks and research firms. Key metrics to watch include the consensus price target (average, high, and low estimates), the number of analysts covering the stock, any recent rating changes (upgrades or downgrades), and how actual earnings compare to analyst estimates (beat or miss history). Our platform aggregates these from multiple data providers for a comprehensive view.

What is DYAI's market cap?

Market capitalization (market cap) for DYAI is calculated by multiplying the current share price by the total number of outstanding shares. It represents the market's total valuation of the company. Stocks are typically categorized as mega-cap ($200B+), large-cap ($10B-$200B), mid-cap ($2B-$10B), small-cap ($300M-$2B), or micro-cap (under $300M). Market cap influences index inclusion, institutional ownership eligibility, and risk profile. Our Key Statistics section shows DYAI's current market cap alongside enterprise value and other valuation metrics.

How has DYAI stock performed recently?

DYAI's recent stock performance can be evaluated across multiple timeframes: daily price changes, week-over-week momentum, monthly trends, and year-to-date returns. Important performance indicators include the stock's 52-week high and low, moving averages (50-day and 200-day SMA), relative strength index (RSI), and volume trends. Comparing DYAI's performance against its sector index and the S&P 500 provides context on whether it is outperforming or underperforming the broader market.

What are the risks of investing in DYAI?

Key risk categories for DYAI include: market risk (overall market downturns affecting stock prices), company-specific risk (management changes, product failures, competitive threats), financial risk (high debt levels, cash burn, dilution from stock issuance), regulatory risk (government policy changes, lawsuits, compliance issues), and macroeconomic risk (interest rate changes, inflation, currency fluctuations). Beta measures DYAI's volatility relative to the market - a beta above 1.0 means higher volatility than the S&P 500. Our AI-generated risk assessment identifies the most relevant risk factors for this specific stock.

Are insiders buying or selling DYAI?

Insider trading activity for DYAI tracks purchases and sales by company executives, directors, and major shareholders (10%+ owners) as reported in SEC Form 4 filings. Insider buying is generally considered a bullish signal because insiders have the deepest knowledge of company operations, while selling may have various motivations (diversification, tax planning, pre-planned 10b5-1 trading plans). Key metrics include the buy-to-sell ratio, total dollar value of insider transactions, and whether multiple insiders are trading in the same direction. Our Insider Flow tab shows recent transactions with dates and dollar amounts.

Is DYAI a good stock for beginners?

Dyadic International, Inc. (DYAI) can be suitable for beginner investors depending on several factors. Look at the MoonshotScore on this page for an overall AI-powered assessment of growth potential and risk. Beginners should also check the company's market cap (larger companies tend to be less volatile), gross margin (higher margins mean stronger business fundamentals), and cash position (healthy cash reduces bankruptcy risk). Always start with a small position size and never invest money you cannot afford to lose.

How risky is DYAI for first-time investors?

Every stock carries risk, including Dyadic International, Inc. (DYAI). First-time investors should review the Risk Factors section on this page for company-specific risks. Key risk indicators include price volatility (check the chart for daily swings), insider selling activity (see Insider Flow tab), and cash runway (see MoonshotScore breakdown). A diversified portfolio with an index fund like the S&P 500 as a core holding is generally recommended before adding individual stocks like DYAI.

Disclaimer: This content is for informational purposes only and does not constitute investment advice. Always do your own research and consult a financial advisor.

Data provided for informational purposes only.

AI Analysis Notes
  • Stock data pending update.
Data Sources
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